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This paper develops Bayesian sample size formulae for experiments comparing two groups. We assume the experimental data will be analysed in the Bayesian framework, where pre-experimental information from multiple sources can be represented…

Methodology · Statistics 2022-03-09 Haiyan Zheng , Thomas Jaki , James M. S. Wason

Differential privacy is a restriction on data processing algorithms that provides strong confidentiality guarantees for individual records in the data. However, research on proper statistical inference, that is, research on properly…

Cryptography and Security · Computer Science 2021-07-06 Joerg Drechsler , Ira Globus-Harris , Audra McMillan , Jayshree Sarathy , Adam Smith

The fraction nonconforming is a key quality measure used in statistical quality control design in clinical laboratory medicine. The confidence bounds of normal populations of measurements for the fraction nonconforming each of the lower and…

Computational Engineering, Finance, and Science · Computer Science 2023-11-07 Aristides T. Hatjimihail

Estimating causal effects from large experimental and observational data has become increasingly prevalent in both industry and research. The bootstrap is an intuitive and powerful technique used to construct standard errors and confidence…

Methodology · Statistics 2023-02-07 Matthew Kosko , Lin Wang , Michele Santacatterina

We formulate a novel approach to solve a class of stochastic problems, referred to as data-consistent inverse (DCI) problems, which involve the characterization of a probability measure on the parameters of a computational model whose…

Numerical Analysis · Mathematics 2024-04-19 Kirana Bergstrom , Troy Butler , Tim Wildey

The standard confidence interval for a population proportion covered in the overwhelming majority of introductory and intermediate statistics textbooks surprisingly remains the Wald confidence interval despite having a poor coverage…

Methodology · Statistics 2025-08-15 Nabil Kahouadji

We present improved methods for calculating confidence intervals and $p$-values in situations where standard asymptotic approaches fail due to small sample sizes. We apply these techniques to a specific class of statistical model that can…

Data Analysis, Statistics and Probability · Physics 2024-01-11 Enzo Canonero , Alessandra Rosalba Brazzale , Glen Cowan

Estimating causal effects from randomized experiments is central to clinical research. Reducing the statistical uncertainty in these analyses is an important objective for statisticians. Registries, prior trials, and health records…

Machine Learning · Statistics 2021-12-06 Alejandro Schuler , David Walsh , Diana Hall , Jon Walsh , Charles Fisher

Conformal prediction provides distribution-free predictive intervals with finite-sample marginal coverage. However, achieving conditional validity and interval efficiency (in terms of short interval length) remains challenging, particularly…

Machine Learning · Statistics 2026-05-06 Ran Zou , Wanrong Zhu , Bin Nan

In this paper, we use the dimensional reduction technique to study the central limit theory (CLT) random quadratic forms based on sample means and sample covariance matrices. Specifically, we use a matrix denoted by $U_{p\times q}$, to map…

Statistics Theory · Mathematics 2022-10-21 Wenzhi Yang , Yiming Liu , Guangming Pan , Wang Zhou

Contemporary statistical publications rely on simulation to evaluate performance of new methods and compare them with established methods. In the context of meta-analysis of log-odds-ratios, we investigate how the ways in which simulations…

Methodology · Statistics 2020-07-06 Elena Kulinskaya , David C. Hoaglin , Ilyas Bakbergenuly

Quadratic discriminant analysis (QDA) is a simple method to classify a subject into two populations, and was proven to perform as well as the Bayes rule when the data dimension p is fixed. The main purpose of this paper is to examine the…

Statistics Theory · Mathematics 2018-08-31 Qing Yang , Guang Cheng

Informative interim adaptations lead to random sample sizes. The random sample size becomes a component of the sufficient statistic and estimation based solely on observed samples or on the likelihood function does not use all available…

Methodology · Statistics 2022-10-25 Sergey Tarima , Nancy Flournoy

In the past two decades, there has been a fast-growing literature on fiducial inference since it was first proposed by R. A. Fisher in the 1930s. However, most of the fiducial inference based methods and related approaches have been…

Methodology · Statistics 2025-01-03 Yifan Cui , Jan Hannig

Most clinical trials conducted in drug development contain multiple endpoints in order to collectively assess the intended effects of the drug on various disease characteristics. Focusing on the estimation of the global win probability,…

Methodology · Statistics 2024-04-09 Di Shu , Guangyong Zou

Pearson's chi-squared test is widely used to test the goodness of fit between categorical data and a given discrete distribution function. When the number of sets of the categorical data, say $k$, is a fixed integer, Pearson's chi-squared…

Methodology · Statistics 2022-01-03 Shuhua Chang , Deli Li , Yongcheng Qi

Comparing the mean vectors across different groups is a cornerstone in the realm of multivariate statistics, with quadratic forms commonly serving as test statistics. However, when the overall hypothesis is rejected, identifying specific…

Methodology · Statistics 2025-06-04 Paavo Sattler , Markus Pauly , Merle Munko

Ratio-based biomarkers (RBBs), such as the proportion of necrotic tissue within a tumor, are widely used in clinical practice to support diagnosis, prognosis, and treatment planning. These biomarkers are typically estimated from…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Jiameng Li , Teodora Popordanoska , Aleksei Tiulpin , Sebastian G. Gruber , Frederik Maes , Matthew B. Blaschko

This paper proposes a decorrelation-based approach to test hypotheses and construct confidence intervals for the low dimensional component of high dimensional proportional hazards models. Motivated by the geometric projection principle, we…

Machine Learning · Statistics 2014-12-17 Ethan X. Fang , Yang Ning , Han Liu

[See paper for full abstract] Meta-analysis is a crucial tool for answering scientific questions. It is usually conducted on a relatively small amount of ``trusted'' data -- ideally from randomized, controlled trials -- which allow causal…

Machine Learning · Statistics 2024-07-15 Shiva Kaul , Geoffrey J. Gordon