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Topological Data Analysis has grown in popularity in recent years as a way to apply tools from algebraic topology to large data sets. One of the main tools in topological data analysis is persistent homology. This paper uses undergraduate…

Algebraic Topology · Mathematics 2024-06-26 Cheyne Glass , Elizabeth Vidaurre

Topological Data Analysis (TDA) has been praised by researchers for its ability to capture intricate shapes and structures within data. TDA is considered robust in handling noisy and high-dimensional datasets, and its interpretability is…

Machine Learning · Computer Science 2024-01-10 Funmilola Mary Taiwo , Umar Islambekov , Cuneyt Gurcan Akcora

Topological data analysis (TDA) is a branch of computational mathematics, bridging algebraic topology and data science, that provides compact, noise-robust representations of complex structures. Deep neural networks (DNNs) learn millions of…

The combination of persistent homology and discrete Morse theory has proven very effective in visualizing and analyzing big and heterogeneous data. Indeed, topology provides computable and coarse summaries of data independently from…

Computational Geometry · Computer Science 2021-02-12 Claudia Landi , Sara Scaramuccia

Persistent homology is a popular computational tool for analyzing the topology of point clouds, such as the presence of loops or voids. However, many real-world datasets with low intrinsic dimensionality reside in an ambient space of much…

Machine Learning · Computer Science 2024-11-01 Sebastian Damrich , Philipp Berens , Dmitry Kobak

Persistent homology computes the multiscale topology of a data set by using a sequence of discrete complexes. In this paper, we propose that persistent homology may be a useful tool for studying the structure of the landscape of string…

High Energy Physics - Theory · Physics 2019-04-24 Alex Cole , Gary Shiu

Persistent homology has emerged as a popular technique for the topological simplification of big data, including biomolecular data. Multidimensional persistence bears considerable promise to bridge the gap between geometry and topology.…

Biomolecules · Quantitative Biology 2014-12-25 Kelin Xia , Guo-Wei Wei

In this chapter, we discuss applications of topological data analysis (TDA) to spatial systems. We briefly review the recently proposed level-set construction of filtered simplicial complexes, and we then examine persistent homology in two…

Social and Information Networks · Computer Science 2021-04-06 Michelle Feng , Abigail Hickok , Mason A. Porter

Many datasets can be viewed as a noisy sampling of an underlying space, and tools from topological data analysis can characterize this structure for the purpose of knowledge discovery. One such tool is persistent homology, which provides a…

Persistent homology (PH) is one of the most popular tools in topological data analysis (TDA), while graph theory has had a significant impact on data science. Our earlier work introduced the persistent spectral graph (PSG) theory as a…

Algebraic Topology · Mathematics 2020-12-22 Rui Wang , Rundong Zhao , Emily Ribando-Gros , Jiahui Chen , Yiying Tong , Guo-Wei Wei

This article proposes a topological method that extracts hierarchical structures of various amorphous solids. The method is based on the persistence diagram (PD), a mathematical tool for capturing shapes of multiscale data. The input to the…

Understanding the structure of high-dimensional data is fundamental to neuroscience and other data-intensive scientific fields. While persistent homology effectively identifies basic topological features such as "holes," it lacks the…

Algebraic Topology · Mathematics 2025-07-16 Ekaterina S. Ivshina , Galit Anikeeva , Ling Zhou

"Concurrence topology" (Ellis and Klein \emph{Homology, Homotopy, and Applications,} \textbf{16}) is a TDA method for binary data. The idea is to construct a filtration consisting of Dowker complexes then compute persistent homology.…

Statistics Theory · Mathematics 2017-06-21 Steven P. Ellis

Topological data analysis (TDA) detects geometric structure in biological data. However, many TDA algorithms are memory intensive and impractical for massive datasets. Here, we introduce a statistical protocol that reduces TDA's memory…

Quantitative Methods · Quantitative Biology 2025-09-05 Andrew J. Stier , Naichen Shi , Raed Al Kontar , Chad Giusti , Marc G. Berman

Topological data analysis can extract effective information from higher-dimensional data. Its mathematical basis is persistent homology. The persistent homology can calculate topological features at different spatiotemporal scales of the…

Algebraic Topology · Mathematics 2023-09-29 Dinghua Shi , Zhifeng Chen , Chuang Ma , Guanrong Chen

Multidimensional persistence studies topological features of shapes by analyzing the lower level sets of vector-valued functions. The rank invariant completely determines the multidimensional analogue of persistent homology groups. We prove…

Algebraic Topology · Mathematics 2009-08-04 Andrea Cerri , Barbara Di Fabio , Massimo Ferri , Patrizio Frosini , Claudia Landi

Topological Data Analysis (TDA) refers to an approach that uses concepts from algebraic topology to study the "shapes" of datasets. The main focus of this paper is persistent homology, a ubiquitous tool in TDA. Basing our study on this, we…

Probability · Mathematics 2016-04-15 Takashi Owada

Spatial transcriptomics (ST) measures gene expression at a set of spatial locations in a tissue. Communities of nearby cells that express similar genes form \textit{spatial domains}. Specialized ST clustering algorithms have been developed…

Quantitative Methods · Quantitative Biology 2025-11-12 Perry Beamer , Zixuan Cang

The effectiveness of Spatio-temporal Graph Neural Networks (STGNNs) in time-series applications is often limited by their dependence on fixed, hand-crafted input graph structures. Motivated by insights from the Topological Data Analysis…

Machine Learning · Computer Science 2025-03-20 Viet The Nguyen , Duy Anh Pham , An Thai Le , Jans Peter , Gunther Gust

Spatial transcriptomics studies are becoming increasingly large and commonplace, necessitating simultaneous analysis of a large number of spatially resolved variables. Correspondingly, a diverse range of methodologies have been proposed to…

Quantitative Methods · Quantitative Biology 2025-09-09 James Boyle , Gregory Hamm , Eleanor Williams , Robin JG Hartman , Magnus Soderburg , Ian Henry , Michael Casey
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