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AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

Stochastic Gradient Descent (SGD) and its variants underpin modern machine learning by enabling efficient optimization of large-scale models. However, their local search nature limits exploration in complex landscapes. In this paper, we…

Quantum Physics · Physics 2025-07-22 Sirui Peng , Shengminjie Chen , Xiaoming Sun , Hongyi Zhou

At present, several models for quantum computation have been proposed. Adiabatic quantum computation scheme particularly offers this possibility and is based on a slow enough time evolution of the system, where no transitions take place. In…

Quantum Physics · Physics 2012-10-12 P. J. Salas Peralta

Quantum chemistry and materials science are among the most promising areas for demonstrating algorithmic quantum advantage and quantum utility due to their inherent quantum mechanical nature. Still, large-scale simulations of quantum…

Quantum computation has emerged as a powerful computational medium of our time, having demonstrated the remarkable efficiency in factoring a positive integer and searching databases faster than any currently known classical computing…

Quantum Physics · Physics 2024-04-16 Tomoyuki Yamakami

A major challenge facing adiabatic quantum computing is that algorithm design and error correction can be difficult for adiabatic quantum computing. Recent work has considered addressing his challenge by using coherently controlled…

Quantum Physics · Physics 2015-06-19 Maria Kieferova , Nathan Wiebe

We propose digitized-counterdiabatic quantum optimization (DCQO) to achieve polynomial enhancement over adiabatic quantum optimization for the general Ising spin-glass model, which includes the whole class of combinatorial optimization…

Quantum Physics · Physics 2023-01-12 Narendra N. Hegade , Xi Chen , Enrique Solano

Quantum algorithms are prominent in the pursuit of achieving quantum advantage in various computational tasks. However, addressing challenges, such as limited qubit coherence and high error rate in near-term devices, requires extensive…

Quantum Physics · Physics 2024-07-31 Julián Ferreiro-Vélez , Iñaki Iriarte-Zendoia , Yue Ban , Xi Chen

Quantum annealing is a continuous-time heuristic quantum algorithm for solving or approximately solving classical optimization problems. The algorithm uses a schedule to interpolate between a driver Hamiltonian with an easy-to-prepare…

Quantum computing holds the potential for quantum advantage in optimization problems, which requires advances in quantum algorithms and hardware specifications. Adiabatic quantum optimization is conceptually a valid solution that suffers…

Time evolution of quantum systems is accelerated by the fast-forward scaling. We reformulate the method to study systems in a finite-dimensional Hilbert space. For several simple systems, we explicitly construct the acceleration potential.…

Quantum Physics · Physics 2014-04-24 Kazutaka Takahashi

The quantum approximate optimization algorithm (QAOA) has proved to be an effective classical-quantum algorithm serving multiple purposes, from solving combinatorial optimization problems to finding the ground state of many-body quantum…

Quantum Physics · Physics 2022-03-08 P. Chandarana , N. N. Hegade , K. Paul , F. Albarrán-Arriagada , E. Solano , A. del Campo , Xi Chen

Qubit-based variational quantum algorithms have undergone rapid development in recent years but still face several challenges. In this context, we propose a symmetry-enhanced digitized counterdiabatic quantum algorithm utilizing qudits…

Quantum adiabatic evolution is a dynamical evolution of a quantum system under slow external driving. According to the quantum adiabatic theorem, no transitions occur between non-degenerate instantaneous eigen-energy levels in such a…

Quantum Physics · Physics 2015-06-18 Qi Zhang , Jiangbin Gong , Biao Wu

The quantum speed limit specifies a universal bound of the fidelity between the initial state and the time-evolved state. We apply this method to find a bound of the fidelity between the adiabatic state and the time-evolved state. The bound…

Quantum Physics · Physics 2020-07-22 Keisuke Suzuki , Kazutaka Takahashi

The success of adiabatic quantum computation (AQC) depends crucially on the ability to maintain the quantum computer in the ground state of the evolution Hamiltonian. The computation process has to be sufficiently slow as restricted by the…

Quantum Physics · Physics 2008-07-31 Man-Hong Yung

A $\textit{shortcut to adiabaticity}$ is a recipe for generating adiabatic evolution at an arbitrary pace. Shortcuts have been developed for quantum, classical and (most recently) stochastic dynamics. A shortcut might involve a…

Quantum Physics · Physics 2017-10-30 Ayoti Patra , Christopher Jarzynski

We introduce an adiabatic state preparation protocol which implements quantum imaginary time evolution under the Hamiltonian of the system. Unlike the original quantum imaginary time evolution algorithm, adiabatic quantum imaginary time…

Quantum Physics · Physics 2024-04-23 Kasra Hejazi , Mario Motta , Garnet Kin-Lic Chan

We propose a new variational quantum algorithm, which we refer to as TIMES-ADAPT, that prepares time-evolved states in a low-energy or symmetric subspace of a time-independent Hamiltonian on a quantum computer. Using a specially trained…

A typical goal of a quantum simulation is to find the energy levels and eigenstates of a given Hamiltonian. This can be realized by adiabatically varying the system control parameters to steer an initial eigenstate into the eigenstate of…

Quantum Physics · Physics 2021-01-04 Gian Salis , Nikolaj Moll , Marco Roth , Marc Ganzhorn , Stefan Filipp