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Deep learning models have achieved great success on various vision challenges, but a well-trained model would face drastic performance degradation when applied to unseen data. Since the model is sensitive to domain shift, unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2025-10-24 Ziyu Ye , Chen Ju , Chaofan Ma , Xiaoyun Zhang

Denoising diffusion probabilistic models (DDPMs) have been proven capable of synthesizing high-quality images with remarkable diversity when trained on large amounts of data. Typical diffusion models and modern large-scale conditional…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Jingyuan Zhu , Huimin Ma , Jiansheng Chen , Jian Yuan

In this paper, we present DRANet, a network architecture that disentangles image representations and transfers the visual attributes in a latent space for unsupervised cross-domain adaptation. Unlike the existing domain adaptation methods…

Computer Vision and Pattern Recognition · Computer Science 2021-03-30 Seunghun Lee , Sunghyun Cho , Sunghoon Im

Human and animal tissues consist of heterogeneous cell types that organize and interact in highly structured manners. Bulk and single-cell sequencing technologies remove cells from their original microenvironments, resulting in a loss of…

Quantitative Methods · Quantitative Biology 2022-02-08 Boxiang Liu , Yanjun Li , Liang Zhang

A deep learning model trained on some labeled data from a certain source domain generally performs poorly on data from different target domains due to domain shifts. Unsupervised domain adaptation methods address this problem by alleviating…

Image and Video Processing · Electrical Eng. & Systems 2019-08-30 Junlin Yang , Nicha C. Dvornek , Fan Zhang , Julius Chapiro , MingDe Lin , James S. Duncan

Medical data often exhibits distribution shifts, which cause test-time performance degradation for deep learning models trained using standard supervised learning pipelines. This challenge is addressed in the field of Domain Generalization…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Aleksandr Matsun , Numan Saeed , Fadillah Adamsyah Maani , Mohammad Yaqub

Spatial transcriptomics (ST) has emerged as an advanced technology that provides spatial context to gene expression. Recently, deep learning-based methods have shown the capability to predict gene expression from WSI data using ST data.…

Machine Learning · Computer Science 2024-12-10 Mingcheng Qu , Yuncong Wu , Donglin Di , Anyang Su , Tonghua Su , Yang Song , Lei Fan

With the aim to improve the performance of feature matching, we present an unsupervised approach to fuse various local descriptors in the space of homographies. Inspired by the observation that the homographies of correct feature…

Computer Vision and Pattern Recognition · Computer Science 2014-12-16 Yuan-Ting Hu , Yen-Yu Lin , Hsin-Yi Chen , Kuang-Jui Hsu , Bing-Yu Chen

Spatial transcriptomics (ST) is essential for understanding diseases and developing novel treatments. It measures gene expression of each fine-grained area (i.e., different windows) in the tissue slide with low throughput. This paper…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Yan Yang , Md Zakir Hossain , Eric A Stone , Shafin Rahman

Genomic phenotypes, such as DNA methylation and chromatin accessibility, can be used to characterize the transcriptional and regulatory activity of DNA within a cell. Recent technological advances have made it possible to measure such…

Methodology · Statistics 2016-11-15 Jean Morrison , Noah Simon , Daniela Witten

In open-world scenarios, where both novel classes and domains may exist, an ideal segmentation model should detect anomaly classes for safety and generalize to new domains. However, existing methods often struggle to distinguish between…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Zhitong Gao , Bingnan Li , Mathieu Salzmann , Xuming He

Spatial transcriptomics (ST) enables transcriptome-wide profiling while preserving the spatial context of tissues, offering unprecedented opportunities to study tissue organization and cell-cell interactions in situ. Despite recent…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Wei Wang , Quoc-Toan Ly , Chong Yu , Jun Bai

Domain generalization addresses domain shift in real-world applications. Most approaches adopt a domain angle, seeking invariant representation across domains by aligning their marginal distributions, irrespective of individual classes,…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Meng Cao , Songcan Chen

Domain Generalized Semantic Segmentation (DGSS) seeks to utilize source domain data exclusively to enhance the generalization of semantic segmentation across unknown target domains. Prevailing studies predominantly concentrate on feature…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Hongwei Niu , Linhuang Xie , Jianghang Lin , Shengchuan Zhang

Spatial transcriptomics has the potential to transform our understanding of RNA expression in tissues. Classical array-based technologies produce multiple-cell-scale measurements requiring deconvolution to recover single cell information.…

Supervised learning with large scale labeled datasets and deep layered models has made a paradigm shift in diverse areas in learning and recognition. However, this approach still suffers generalization issues under the presence of a domain…

Machine Learning · Statistics 2016-03-28 Ozan Sener , Hyun Oh Song , Ashutosh Saxena , Silvio Savarese

Open-set single-source domain generalization aims to use a single-source domain to learn a robust model that can be generalized to unknown target domains with both domain shifts and label shifts. The scarcity of the source domain and the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-06 Pengkun Jiao , Na Zhao , Jingjing Chen , Yu-Gang Jiang

Identifying concentrations of components from an observed mixture is a fundamental problem in signal processing. It has diverse applications in fields ranging from hyperspectral imaging to denoising biomedical sensors. This paper focuses on…

Computational Engineering, Finance, and Science · Computer Science 2016-11-17 Shahin Mohammadi , Neta Zuckerman , Andrea Goldsmith , Ananth Grama

Accurate medical image segmentation is essential for effective diagnosis and treatment planning but is often challenged by domain shifts caused by variations in imaging devices, acquisition conditions, and patient-specific attributes.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Jie Bao , Zhixin Zhou , Wen Jung Li , Rui Luo

Self-supervised learning has demonstrated considerable potential in hyperspectral representation, yet its application in cross-domain transfer scenarios remains under-explored. Existing methods, however, still rely on source domain…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Jianshu Chao , Tianhua Lv , Qiqiong Ma , Yunfei Qiu , Li Fang , Huifang Shen , Wei Yao
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