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Perfusion imaging (PI) is clinically used to assess strokes and brain tumors. Commonly used PI approaches based on magnetic resonance imaging (MRI) or computed tomography (CT) measure the effect of a contrast agent moving through blood…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Peirong Liu , Yueh Z. Lee , Stephen R. Aylward , Marc Niethammer

Autofocus is necessary for high-throughput and real-time scanning in microscopic imaging. Traditional methods rely on complex hardware or iterative hill-climbing algorithms. Recent learning-based approaches have demonstrated remarkable…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Yongping Zhai , Xiaoxi Fu , Qiang Su , Jia Hu , Yake Zhang , Yunfeng Zhou , Chaofan Zhang , Xiao Li , Wenxin Wang , Dongdong Wu , Shen Yan

Single Photon Emission Computed Tomography (SPECT) is a non-invasive imaging modality, frequently used in myocardial perfusion imaging. The biggest challenges facing the majority of clinical SPECT systems are low sensitivity, poor…

Medical Physics · Physics 2021-03-30 Narayan Bhusal

Despite offering high sensitivity, a high signal-to-noise ratio, and a broad spectral range, single-pixel imaging (SPI) is limited by low measurement efficiency and long data-acquisition times. To address this, we propose a…

We present a novel approach to implement compressive sensing in laser scanning microscopes (LSM), specifically in image scanning microscopy (ISM), using a single-photon avalanche diode (SPAD) array detector. Our method addresses two…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Ajay Gunalan , Marco Castello , Simonluca Piazza , Shunlei Li , Alberto Diaspro , Leonardo S. Mattos , Paolo Bianchini

Photoacoustic microscopy (PAM) has been a promising biomedical imaging technology in recent years. However, the point-by-point scanning mechanism results in low-speed imaging, which limits the application of PAM. Reducing sampling density…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Jiasheng Zhou , Da He , Xiaoyu Shang , Zhendong Guo , Sung-liang Chen , Jiajia Luo

Sparse-View Computed Tomography (SVCT) offers low-dose and fast imaging but suffers from severe artifacts. Optimizing the sampling strategy is an essential approach to improving the imaging quality of SVCT. However, current methods…

Image and Video Processing · Electrical Eng. & Systems 2024-09-04 Liutao Yang , Jiahao Huang , Yingying Fang , Angelica I Aviles-Rivero , Carola-Bibiane Schonlieb , Daoqiang Zhang , Guang Yang

Computed Tomography (CT) technology reduces radiation haz-ards to the human body through sparse sampling, but fewer sampling angles pose challenges for image reconstruction. Score-based generative models are widely used in sparse-view CT…

Image and Video Processing · Electrical Eng. & Systems 2025-12-22 Junyan Zhang , Mengxiao Geng , Pinhuang Tan , Yi Liu , Zhili Liu , Bin Huang , Qiegen Liu

This is a preprint. The latest version has been published here: https://pubs.rsna.org/doi/10.1148/ryai.230275 Purpose: Sparse-view computed tomography (CT) is an effective way to reduce dose by lowering the total number of views acquired,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Johannes Thalhammer , Manuel Schultheiss , Tina Dorosti , Tobias Lasser , Franz Pfeiffer , Daniela Pfeiffer , Florian Schaff

Ultrasound super-localization microscopy techniques presented in the last few years enable non-invasive imaging of vascular structures at the capillary level by tracking the flow of ultrasound contrast agents (gas microbubbles). However,…

Tissues and Organs · Quantitative Biology 2016-08-10 Avinoam Bar-Zion , Charles Tremblay-Darveau , Oren Solomon , Dan Adam , Yonina C. Eldar

In SPECT image reconstruction, limited-angle (LA) conditions lead to a loss of frequency components, which distort the reconstructed tomographic image along directions corresponding to the non-collected projection angle range. Although…

Medical Physics · Physics 2025-07-16 Kensuke Hori , Fumio Hashimoto , Kazuya Koyama , Takeyuki Hashimoto

Photoacoustic(PA) imaging is a non-destructive and non-invasive technology for visualizing minute blood vessel structures in the body using ultrasonic sensors. In PA imaging, the image quality of a single-shot image is poor, and it is…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Tatsuhiro Eguchi , Shumpei Takezaki , Mihoko Shimano , Takayuki Yagi , Ryoma Bise

Background. Percutaneous coronary intervention(PCI) in stable coronary artery disease(CAD) is commonly triggered by abnormal myocardial perfusion imaging(MPI). However, due to the possibilities of multivessel disease and variability of…

Medical Physics · Physics 2020-06-15 Haipeng Tang , Robert R. Bober , Chen Zhao , Chaoyang Zhang , Huiqing Zhu , Zhuo He , Zhihui Xu , Weihua Zhou

Ultrasound computed tomography (USCT) is a promising technique that achieves superior medical imaging reconstruction resolution by fully leveraging waveform information, outperforming conventional ultrasound methods. Despite its advantages,…

Image and Video Processing · Electrical Eng. & Systems 2024-07-23 Yi Sheng , Hanchen Wang , Yipei Liu , Junhuan Yang , Weiwen Jiang , Youzuo Lin , Lei Yang

Coronary artery disease (CAD) is a cardiovascular condition with high morbidity and mortality. Intravascular optical coherence tomography (IVOCT) has been considered as an optimal imagining system for the diagnosis and treatment of CAD.…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Xueshen Li , Shengting Cao , Hongshan Liu , Xinwen Yao , Brigitta C. Brott , Silvio H. Litovsky , Xiaoyu Song , Yuye Ling , Yu Gan

Anisotropic Diffusion is widely used for noise reduction with simultaneous preservation of vascular structures in maximum intensity projected (MIP) angiograms. However, extension to minimum intensity projected (mIP) venograms in…

Computer Vision and Pattern Recognition · Computer Science 2015-01-15 P. K. Akshara , J. S. Paul

Magnetic particle imaging (MPI) is an in-vivo imaging method to detect magnetic nanoparticles for blood vessel imaging and molecular target imaging. Compared with conventional molecular imaging devices (such as nuclear medicine imaging PET…

Medical Physics · Physics 2024-04-26 Guang Jia , Zhongwei Bian , Tianshu Li , Shi Bai , Chenxing Hu , Lixuan Zhao , Peng Gao , Tanping Li , Hui Hui , Jie Tian

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

Medical Physics · Physics 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

A successful approach to image quality assessment involves comparing the structural information between a distorted and its reference image. However, extracting structural information that is perceptually important to our visual system is a…

Computer Vision and Pattern Recognition · Computer Science 2021-03-17 Tanaya Guha , Ehsan Nezhadarya , Rabab K Ward

Visualization of the in vivo spatial distribution of superparamagnetic iron oxide nanoparticles (SPIONs) is crucial to biomedicine. Magnetic particle imaging (MPI) is one of the most promising approaches for direct measurements of the SPION…

Medical Physics · Physics 2022-07-13 Klaas-Julian Janssen , Meinhard Schilling , Frank Ludwig , Jing Zhong