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External information, such as prior information or expert opinions, can play an important role in the design, analysis and interpretation of clinical trials. However, little attention has been devoted thus far to incorporating external…

Applications · Statistics 2013-04-24 Minge Xie , Regina Y. Liu , C. V. Damaraju , William H. Olson

Objective Bayesian inference procedures are derived for the parameters of the multivariate random effects model generalized to elliptically contoured distributions. The posterior for the overall mean vector and the between-study covariance…

Methodology · Statistics 2021-04-07 Olha Bodnar , Taras Bodnar

The Frequentist, Assisted by Bayes (FAB) framework constructs confidence regions that leverage prior information about parameter values. FAB confidence regions (FAB-CRs) have smaller volume for values of the parameter that are likely under…

Methodology · Statistics 2025-07-01 Stefano Cortinovis , François Caron

Large-sample Bayesian analogs exist for many frequentist methods, but are less well-known for the widely-used 'sandwich' or 'robust' variance estimates. We review existing approaches to Bayesian analogs of sandwich variance estimates and…

Methodology · Statistics 2023-11-06 Kendrick Qijun Li , Kenneth Martin Rice

Despite the popularism of Bayesian neural networks in recent years, its use is somewhat limited in complex and big data situations due to the computational cost associated with full posterior evaluations. Variational Bayes (VB) provides a…

Machine Learning · Statistics 2020-06-30 Shrijita Bhattacharya , Tapabrata Maiti

This article is motivated by the problem of inference on interactions among chemical exposures impacting human health outcomes. Chemicals often co-occur in the environment or in synthetic mixtures and as a result exposure levels can be…

Methodology · Statistics 2020-01-09 Federico Ferrari , David B Dunson

Accurate epidemic forecasting is critical for effective public health interventions. This study compares Bayesian and Frequentist estimation frameworks within deterministic compartmental epidemic models, focusing on nonlinear least squares…

Quantitative Methods · Quantitative Biology 2025-09-09 Hamed Karami , Ruiyan Luo , Pejman Sanaei , Gerardo Chowell

As dental caries appear as subtle, low-contrast lesions in intraoral imaging, existing deep learning models face significant challenges in the early detection of caries. While recent Transformer-based detectors have shown promising results…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Xuefen Liu , Xinquan Yang , Mianjie Zheng , Kun Tang , Xuguang Li , Xiaoqi Guo , Linlin Shen , He Meng

Bayesian inference is used extensively to quantify the uncertainty in an inferred field given the measurement of a related field when the two are linked by a mathematical model. Despite its many applications, Bayesian inference faces…

Machine Learning · Statistics 2020-03-31 Dhruv V. Patel , Assad A. Oberai

Accurate dental caries detection from panoramic X-rays plays a pivotal role in preventing lesion progression. However, current detection methods often yield suboptimal accuracy due to subtle contrast variations and diverse lesion morphology…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Tao Luo , Han Wu , Tong Yang , Dinggang Shen , Zhiming Cui

We propose a joint individualized hurdle-ordinal regression model for paired zero-inflated ordinal outcomes with subject-specific, spatially varying, and time-varying covariate effects, motivated by the Iowa Fluoride Study (IFS). The two…

Methodology · Statistics 2026-05-12 Arkaprava Roy , Jeremy T. Gaskins , Steven Levy , Somnath Datta

A Bayesian analytics framework that precisely quantifies uncertainty offers a significant advance for financial risk management. We develop an integrated approach that consistently enhances the handling of risk in market volatility…

Risk Management · Quantitative Finance 2025-12-19 Sharif Al Mamun , Rakib Hossain , Md. Jobayer Rahman , Malay Kumar Devnath , Farhana Afroz , Lisan Al Amin

Bayesian likelihood-free methods implement Bayesian inference using simulation of data from the model to substitute for intractable likelihood evaluations. Most likelihood-free inference methods replace the full data set with a summary…

Methodology · Statistics 2020-10-16 Yinan Mao , Xueou Wang , David J. Nott , Michael Evans

In many hypothesis testing applications, we have mixed priors, with well-motivated informative priors for some parameters but not for others. The Bayesian methodology uses the Bayes factor and is helpful for the informative priors, as it…

Data Analysis, Statistics and Probability · Physics 2022-10-05 Jakob Robnik , Uroš Seljak

Modern machine learning applications should be able to address the intrinsic challenges arising over inference on massive real-world datasets, including scalability and robustness to outliers. Despite the multiple benefits of Bayesian…

Machine Learning · Computer Science 2020-11-10 Dionysis Manousakas , Cecilia Mascolo

Bayesian hypothesis testing via Bayes factors offers a principled alternative to classical p-value methods in meta-analysis, particularly suited to its cumulative and sequential nature. Unlike commonly reported p-values for standard null…

Methodology · Statistics 2026-04-22 Joris Mulder , Robbie C. M. van Aert

Dental fluorosis is a chronic disease caused by long-term overconsumption of fluoride, which leads to changes in the appearance of tooth enamel. It is an important basis for early non-invasive diagnosis of endemic fluorosis. However, even…

Computer Vision and Pattern Recognition · Computer Science 2024-04-23 Yun Wu , Hao Xu , Maohua Gu , Zhongchuan Jiang , Jun Xu , Youliang Tian

Recent deep learning approaches focus on improving quantitative scores of dedicated benchmarks, and therefore only reduce the observation-related (aleatoric) uncertainty. However, the model-immanent (epistemic) uncertainty is less…

Image and Video Processing · Electrical Eng. & Systems 2021-10-25 Dominik Narnhofer , Alexander Effland , Erich Kobler , Kerstin Hammernik , Florian Knoll , Thomas Pock

In Bayesian statistics, one's prior beliefs about underlying model parameters are revised with the information content of observed data from which, using Bayes' rule, a posterior belief is obtained. A non-trivial example taken from the…

High Energy Physics - Phenomenology · Physics 2007-05-23 J. Charles , A. Hocker , H. Lacker , F. R. Le Diberder , S. T'Jampens

Recent evidence suggests that analyzing the presence/absence of taxonomic features can offer a compelling alternative to differential abundance analysis in microbiome studies. However, standard approaches to differential prevalence analysis…

Methodology · Statistics 2026-05-26 Juho Pelto , Kari Auranen , Janne V. Kujala , Leo Lahti
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