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Persistent homology (PH) characterizes the shape of brain networks through persistence features. Group comparison of persistence features from brain networks can be challenging as they are inherently heterogeneous. A recent scale-space…

Subtle alterations in brain network topology often evade detection by traditional statistical methods. To address this limitation, we introduce a Bayesian inference framework for topological comparison of brain networks that…

Methodology · Statistics 2025-11-06 Xukun Zhu , Michael W Lutz , Tananun Songdechakraiwut

This work introduces a novel framework for testing topological variability in weighted networks by combining Hodge decomposition with Wasserstein variance minimization. Traditional approaches that analyze raw edge weights are susceptible to…

Quantitative Methods · Quantitative Biology 2025-11-18 Sixtus Dakurah

Persistent homology (PH) characterizes the shape of brain networks through the persistence features. Group comparison of persistence features from brain networks can be challenging as they are inherently heterogeneous. A recent scale-space…

Methodology · Statistics 2023-11-06 Yuan Wang , Jian Yin , Rutvik H. Desai

This paper proposes a novel topological learning framework that integrates networks of different sizes and topology through persistent homology. Such challenging task is made possible through the introduction of a computationally efficient…

Neurons and Cognition · Quantitative Biology 2023-01-30 Tananun Songdechakraiwut , Moo K. Chung

Developing reliable methods to discriminate different transient brain states that change over time is a key neuroscientific challenge in brain imaging studies. Topological data analysis (TDA), a novel framework based on algebraic topology,…

Neurons and Cognition · Quantitative Biology 2023-12-19 Moo K. Chung , Soumya Das , Hernando Ombao

Persistent homology has been applied to brain network analysis for finding the shape of brain networks across multiple thresholds. In the persistent homology, the shape of networks is often quantified by the sequence of $k$-dimensional…

Quantitative Methods · Quantitative Biology 2018-11-13 Hyekyoung Lee , Moo K. Chung , Hongyoon Choi , Hyejin Kang , Seunggyun Ha , Yu Kyeong Kim , Dong Soo Lee

Persistent homology offers a powerful tool for extracting hidden topological signals from brain networks. It captures the evolution of topological structures across multiple scales, known as filtrations, thereby revealing topological…

Multi-band insulating Bloch Hamiltonians with internal or spatial symmetries, such as particle-hole or inversion, may have topologically disconnected sectors of trivial atomic-limit (momentum-independent) Hamiltonians. We present a…

Disordered Systems and Neural Networks · Physics 2021-04-19 Oleksandr Balabanov , Mats Granath

The study of topological properties by machine learning approaches has attracted considerable interest recently. Here we propose machine learning the topological invariants that are unique in non-Hermitian systems. Specifically, we train…

Computational Physics · Physics 2021-01-27 Ling-Feng Zhang , Ling-Zhi Tang , Zhi-Hao Huang , Guo-Qing Zhang , Wei Huang , Dan-Wei Zhang

Topological invariants are crucial for characterizing topological systems. However, experimentally measuring them presents a significant challenge, especially in non-Hermitian systems where the biorthogonal eigenvectors are often necessary.…

Quantum Physics · Physics 2025-04-23 Shuo Wang , Zhengjie Kang , Hao Li , Jiaojiao Li , Yuanjie Zhang , Zhihuang Luo

We discuss and demonstrate an unsupervised machine-learning procedure to detect topological order in quantum many-body systems. Using a restricted Boltzmann machine to define a variational ansatz for the low-energy spectrum, we sample wave…

Quantum Physics · Physics 2023-11-29 Yanting Teng , Subir Sachdev , Mathias S. Scheurer

Persistent homology is a cornerstone of topological data analysis, offering a multiscale summary of topology with robustness to nuisance transformations, such as rotations and small deformations. Persistent homology has seen broad use…

Methodology · Statistics 2025-11-19 Zitian Wu , Arkaprava Roy , Leo L. Duan

Topological invariants allow to characterize Hamiltonians, predicting the existence of topologically protected in-gap modes. Those invariants can be computed by tracing the evolution of the occupied wavefunctions under twisted boundary…

Mesoscale and Nanoscale Physics · Physics 2018-04-04 D. Carvalho , N. A. Garcia-Martinez , J. L. Lado , J. Fernandez-Rossier

We use methods from computational algebraic topology to study functional brain networks, in which nodes represent brain regions and weighted edges encode the similarity of fMRI time series from each region. With these tools, which allow one…

Quantitative Methods · Quantitative Biology 2020-08-27 Bernadette J. Stolz , Tegan Emerson , Satu Nahkuri , Mason A. Porter , Heather A. Harrington

Mild cognitive impairment (MCI) is characterized by subtle changes in cognitive functions, often associated with disruptions in brain connectivity. The present study introduces a novel fine-grained analysis to examine topological…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Ninad Aithal , Debanjali Bhattacharya , Neelam Sinha , Thomas Gregor Issac

Recently, graph theory has become a popular method for characterizing brain functional organization. One important goal in graph theoretical analysis of brain networks is to identify network differences across disease types or conditions.…

Applications · Statistics 2018-10-01 Ixavier A Higgins , Ying Guo , Suprateek Kundu , Ki Sueng Choi , Helen Mayberg

Understanding the common topological characteristics of the human brain network across a population is central to understanding brain functions. The abstraction of human connectome as a graph has been pivotal in gaining insights on the…

Quantitative Methods · Quantitative Biology 2023-04-26 Soumya Das , D. Vijay Anand , Moo K. Chung

We consider the problem of testing positively dependent multiple hypotheses assuming that a prior information about the dependence structure is available. We propose two-step multiple comparisons procedures that exploit the prior…

We introduce an innovative, data-driven topological data analysis (TDA) technique for estimating the state spaces of dynamically changing functional human brain networks at rest. Our method utilizes the Wasserstein distance to measure…

Algebraic Topology · Mathematics 2024-04-18 Moo K. Chung , Shih-Gu Huang , Ian C. Carroll , Vince D. Calhoun , H. Hill Goldsmith
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