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Variational Autoencoders (VAE) and their variants have been widely used in a variety of applications, such as dialog generation, image generation and disentangled representation learning. However, the existing VAE models have some…

Machine Learning · Computer Science 2020-06-23 Huajie Shao , Shuochao Yao , Dachun Sun , Aston Zhang , Shengzhong Liu , Dongxin Liu , Jun Wang , Tarek Abdelzaher

Disentangled representations enable models to separate factors of variation that are shared across experimental conditions from those that are condition-specific. This separation is essential in domains such as biomedical data analysis,…

Machine Learning · Computer Science 2025-12-16 Yuli Slavutsky , Ozgur Beker , David Blei , Bianca Dumitrascu

Learning interpretable and disentangled representations of data is a key topic in machine learning research. Variational Autoencoder (VAE) is a scalable method for learning directed latent variable models of complex data. It employs a clear…

Machine Learning · Computer Science 2020-06-04 Andriy Serdega , Dae-Shik Kim

Image and language modeling is of crucial importance for vision-language pre-training (VLP), which aims to learn multi-modal representations from large-scale paired image-text data. However, we observe that most existing VLP methods focus…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Sunan He , Taian Guo , Tao Dai , Ruizhi Qiao , Chen Wu , Xiujun Shu , Bo Ren

With the explosion of graph-structured data, link prediction has emerged as an increasingly important task. Embedding methods for link prediction utilize neural networks to generate node embeddings, which are subsequently employed to…

Machine Learning · Computer Science 2023-06-21 Jun Fu , Xiaojuan Zhang , Shuang Li , Dali Chen

We propose a novel VAE-based deep auto-encoder model that can learn disentangled latent representations in a fully unsupervised manner, endowed with the ability to identify all meaningful sources of variation and their cardinality. Our…

Machine Learning · Computer Science 2019-02-06 Minyoung Kim , Yuting Wang , Pritish Sahu , Vladimir Pavlovic

Predicting survival outcomes for non-small cell lung cancer (NSCLC) patients is challenging due to the different individual prognostic features. This task can benefit from the integration of whole-slide images, bulk transcriptomics, and DNA…

Disentangling anatomical and contrast information from medical images has gained attention recently, demonstrating benefits for various image analysis tasks. Current methods learn disentangled representations using either paired multi-modal…

Image and Video Processing · Electrical Eng. & Systems 2022-05-11 Lianrui Zuo , Yihao Liu , Yuan Xue , Shuo Han , Murat Bilgel , Susan M. Resnick , Jerry L. Prince , Aaron Carass

Current deep learning-based manifold learning algorithms such as the variational autoencoder (VAE) require fully sampled data to learn the probability density of real-world datasets. Once learned, the density can be used for a variety of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-13 Qing Zou , Abdul Haseeb Ahmed , Prashant Nagpal , Sarv Priya , Rolf Schulte , Mathews Jacob

One major challenge of disentanglement learning with variational autoencoders is the trade-off between disentanglement and reconstruction fidelity. Previous studies, which increase the information bottleneck during training, tend to lose…

Machine Learning · Computer Science 2023-10-05 Jiantao Wu , Shentong Mo , Xiang Yang , Muhammad Awais , Sara Atito , Xingshen Zhang , Lin Wang , Xiang Yang

A variational autoencoder (VAE) is a probabilistic machine learning framework for posterior inference that projects an input set of high-dimensional data to a lower-dimensional, latent space. The latent space learned with a VAE offers…

Machine Learning · Computer Science 2022-11-16 Rafael Pastrana

Vision-language pre-training for chest X-rays has made significant strides, primarily by utilizing paired radiographs and radiology reports. However, existing approaches often face challenges in encoding medical knowledge effectively. While…

Computer Vision and Pattern Recognition · Computer Science 2024-04-05 Haozhe Luo , Ziyu Zhou , Corentin Royer , Anjany Sekuboyina , Bjoern Menze

Medical image synthesis is crucial for alleviating data scarcity and privacy constraints. However, fine-tuning general text-to-image (T2I) models remains challenging, mainly due to the significant modality gap between complex visual details…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Xin Huang , Junjie Liang , Qingshan Hou , Peng Cao , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

Combining neuroimaging datasets from multiple sites and scanners can help increase statistical power and thus provide greater insight into subtle neuroanatomical effects. However, site-specific effects pose a challenge by potentially…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Ayodeji Ijishakin , Ana Lawry Aguila , Elizabeth Levitis , Ahmed Abdulaal , Andre Altmann , James Cole

Evaluating and interpreting latent representations, such as variational autoencoders (VAEs), remains a significant challenge for diverse data types, especially when ground-truth generative factors are unknown. To address this, we propose a…

Machine Learning · Statistics 2026-03-13 Xiaoan Lang , Fang Liu

Disentangled representation learning aims to map independent factors of variation to independent representation components. On one hand, purely unsupervised approaches have proven successful on fully disentangled synthetic data, but fail to…

Machine Learning · Computer Science 2026-01-30 Alexandre Myara , Nicolas Bourriez , Thomas Boyer , Thomas Lemercier , Ihab Bendidi , Auguste Genovesio

Ultra-high-definition (UHD) image restoration often faces computational bottlenecks and information loss due to its extremely high resolution. Existing studies based on Variational Autoencoders (VAE) improve efficiency by transferring the…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Yidi Liu , Dong Li , Yuxin Ma , Jie Huang , Wenlong Zhang , Xueyang Fu , Zheng-jun Zha

Automatic radiology report generation is booming due to its huge application potential for the healthcare industry. However, existing computer vision and natural language processing approaches to tackle this problem are limited in two…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Fudan Zheng , Mengfei Li , Ying Wang , Weijiang Yu , Ruixuan Wang , Zhiguang Chen , Nong Xiao , Yutong Lu

In this paper, we propose a novel model called Learnable VAE (L-VAE), which learns a disentangled representation together with the hyperparameters of the cost function. L-VAE can be considered as an extension of \b{eta}-VAE, wherein the…

Machine Learning · Computer Science 2025-07-04 Hazal Mogultay Ozcan , Sinan Kalkan , Fatos T. Yarman-Vural

Deep latent variable models (DLVMs) are designed to learn meaningful representations in an unsupervised manner, such that the hidden explanatory factors are interpretable by independent latent variables (aka disentanglement). The…

Machine Learning · Computer Science 2025-01-28 Surojit Saha , Sarang Joshi , Ross Whitaker