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Conventional breast cancer imaging techniques are nowadays based on the use of ionising radiations or ultrasound waves for the inspection of breast areas. Nevertheless, these conventional techniques present some drawbacks related to patient…
Prostate cancer is a leading cause of mortality in men, yet interpretation of T2-weighted prostate MRI remains challenging due to subtle and heterogeneous lesions. We developed an interpretable framework for automatic cancer detection using…
Purposes: This study aimed to develop a computed tomography (CT)-based multi-organ segmentation model for delineating organs-at-risk (OARs) in pediatric upper abdominal tumors and evaluate its robustness across multiple datasets. Materials…
Quantitative assessment of treatment response in Advanced Prostate Cancer (APC) with bone metastases remains an unmet clinical need. Whole-Body Diffusion-Weighted MRI (WB-DWI) provides two response biomarkers: Total Diffusion Volume (TDV)…
Magnetic Resonance Imaging (MRI) offers unparalleled soft-tissue contrast but is fundamentally limited by long acquisition times. While deep learning-based accelerated MRI can dramatically shorten scan times, the reconstruction from…
Recent studies on T1-assisted MRI reconstruction for under-sampled images of other modalities have demonstrated the potential of further accelerating MRI acquisition of other modalities. Most of the state-of-the-art approaches have achieved…
Mammography is the most widely used gold standard for screening breast cancer, where, mass detection is considered as the prominent step. Detecting mass in the breast is, however, an arduous problem as they usually have large variations…
We present a deep convolutional neural network for breast cancer screening exam classification, trained and evaluated on over 200,000 exams (over 1,000,000 images). Our network achieves an AUC of 0.895 in predicting whether there is a…
To facilitate early detection of breast cancer, there is a need to develop short-term risk prediction schemes that can prescribe personalized/individualized screening mammography regimens for women. In this study, we propose a new deep…
Regular mammography screening is essential for early breast cancer detection. Deep learning-based risk prediction methods have sparked interest to adjust screening intervals for high-risk groups. While early methods focused only on current…
Purpose: To investigate feasibility of accelerating prostate diffusion-weighted imaging (DWI) by reducing the number of acquired averages and denoising the resulting image using a proposed guided denoising convolutional neural network…
Current imaging-based prostate cancer diagnosis requires both MR T2-weighted (T2w) and diffusion-weighted imaging (DWI) sequences, with additional sequences for potentially greater accuracy improvement. However, measuring diffusion patterns…
Digital Breast Tomosynthesis (DBT) is a widely used medical imaging modality for breast cancer screening and diagnosis, offering higher spatial resolution and greater detail through its 3D-like breast volume imaging capability. However, the…
This work reveals undiscovered challenges in the performance and generalizability of deep learning models. We (1) identify spurious shortcuts and evaluation issues that can inflate performance and (2) propose training and analysis methods…
Purpose: Cell size is a fundamental characteristic of all tissues, and changes in cell size in cancer reflect tumor status and response to treatments, such as apoptosis and cell cycle arrest. Unfortunately, cell size can only be obtained by…
Magnetic Resonance Imaging (MRI) is instrumental in clinical diagnosis, offering diverse contrasts that provide comprehensive diagnostic information. However, acquiring multiple MRI contrasts is often constrained by high costs, long…
This work presents a novel breast cancer imaging approach that uses compressive sensing in a hybrid Digital Breast Tomosynthesis (DBT) / Nearfield Radar Imaging (NRI) system configuration. The non-homogeneous tissue distribution of the…
Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic and radiotherapy (RT) planning tool, offering detailed insights into the anatomy of the human body. The extensive scan time is stressful for patients, who must remain motionless…
Purpose: Risk-stratified breast cancer screening might improve early detection and efficiency without comprising quality. However, modern mammography-based risk models do not ensure adaptation across vendor-domains and rely on cancer…
This paper proposes a robust longitudinal registration method for Contrast Enhanced Spectral Mammography in monitoring neoadjuvant chemotherapy. Because breast texture intensity changes with the treatment, a non-rigid registration procedure…