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For decades, a variety of predictive approaches have been proposed and evaluated in terms of their prediction capability for Alzheimer's Disease (AD) and its precursor - mild cognitive impairment (MCI). Most of them focused on prediction or…
Deep generative modeling has emerged as a powerful tool for synthesizing realistic medical images, driving advances in medical image analysis, disease diagnosis, and treatment planning. This chapter explores various deep generative models…
Super-resolution (SR) and image generation are important tasks in computer vision and are widely adopted in real-world applications. Most existing methods, however, generate images only at fixed-scale magnification and suffer from…
In this work we study how diffusion-based generative models produce high-dimensional data, such as an image, by implicitly relying on a manifestation of a low-dimensional set of latent abstractions, that guide the generative process. We…
This paper introduces a novel generative encoder (GE) model for generative imaging and image processing with applications in compressed sensing and imaging, image compression, denoising, inpainting, deblurring, and super-resolution. The GE…
In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality…
There has been a longstanding belief that generation can facilitate a true understanding of visual data. In line with this, we revisit generatively pre-training visual representations in light of recent interest in denoising diffusion…
We present a novel deep generative model based on non i.i.d. variational autoencoders that captures global dependencies among observations in a fully unsupervised fashion. In contrast to the recent semi-supervised alternatives for global…
The integration of Vector Quantised Variational AutoEncoder (VQ-VAE) with autoregressive models as generation part has yielded high-quality results on image generation. However, the autoregressive models will strictly follow the progressive…
Electroencephalography (EEG) has emerged as a cost-effective and efficient tool to support neurologists in the detection of Alzheimer's Disease (AD). However, most existing approaches rely heavily on manual feature engineering or data…
Autoencoder networks are unsupervised approaches aiming at combining generative and representational properties by learning simultaneously an encoder-generator map. Although studied extensively, the issues of whether they have the same…
We introduce Diffusion Active Learning, a novel approach that combines generative diffusion modeling with data-driven sequential experimental design to adaptively acquire data for inverse problems. Although broadly applicable, we focus on…
Disentangled generative models map a latent code vector to a target space, while enforcing that a subset of the learned latent codes are interpretable and associated with distinct properties of the target distribution. Recent advances have…
As latent diffusion models (LDMs) democratize image generation capabilities, there is a growing need to detect fake images. A good detector should focus on the generative models fingerprints while ignoring image properties such as semantic…
Vector Quantized-Variational AutoEncoders (VQ-VAE) are generative models based on discrete latent representations of the data, where inputs are mapped to a finite set of learned embeddings.To generate new samples, an autoregressive prior…
The application of causal discovery to diseases like Alzheimer's (AD) is limited by the static graph assumptions of most methods; such models cannot account for an evolving pathophysiology, modulated by a latent disease pseudotime. We…
Deep generative models are attracting great attention as a new promising approach for molecular design. All models reported so far are based on either variational autoencoder (VAE) or generative adversarial network (GAN). Here we propose a…
This study addresses the challenge of statistically extracting generative factors from complex, high-dimensional datasets in unsupervised or semi-supervised settings. We investigate encoder-decoder-based generative models for nonlinear…
Latent-based image generative models, such as Latent Diffusion Models (LDMs) and Mask Image Models (MIMs), have achieved notable success in image generation tasks. These models typically leverage reconstructive autoencoders like VQGAN or…
Disentangled representation learning finds compact, independent and easy-to-interpret factors of the data. Learning such has been shown to require an inductive bias, which we explicitly encode in a generative model of images. Specifically,…