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In the last decade, data-driven algorithms outperformed traditional optimization-based algorithms in many research areas, such as computer vision, natural language processing, etc. However, extensive data usages bring a new challenge or…

Machine Learning · Computer Science 2021-12-02 Shih-Chun Lin , Chia-Hung Lin

Federated learning enables collaborative model training across distributed clients while preserving data privacy. However, in practical deployments, device heterogeneity, non-independent, and identically distributed (Non-IID) data often…

Artificial Intelligence · Computer Science 2026-02-20 Jin Wang , Hui Ma , Fei Xing , Ming Yan

Transfer learning has been developed to improve the performances of different but related tasks in machine learning. However, such processes become less efficient with the increase of the size of training data and the number of tasks.…

Machine Learning · Computer Science 2018-03-28 Rui Zhang , Quanyan Zhu

Individualized treatment rules (ITRs) aim to optimize healthcare by tailoring treatment decisions to patient-specific characteristics. Existing methods typically rely on either interpretable but inflexible models or highly flexible…

Methodology · Statistics 2026-02-13 Yasin Khadem Charvadeh , Katherine S. Panageas , Yuan Chen

Continual data collection and widespread deployment of machine learning algorithms, particularly the distributed variants, have raised new privacy challenges. In a distributed machine learning scenario, the dataset is stored among several…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-12-16 Shripad Gade , Nitin H. Vaidya

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

The effects of treatments are often heterogeneous, depending on the observable characteristics, and it is necessary to exploit such heterogeneity to devise individualized treatment rules (ITRs). Existing estimation methods of such ITRs…

Econometrics · Economics 2022-08-09 Daido Kido

In many important applications of precision medicine, the outcome of interest is time to an event (e.g., death, relapse of disease) and the primary goal is to identify the optimal individualized decision rule (IDR) to prolong survival time.…

Methodology · Statistics 2022-04-11 Yu Zhou , Lan Wang , Rui Song , Tuoyi Zhao

While many solutions for privacy-preserving convex empirical risk minimization (ERM) have been developed, privacy-preserving nonconvex ERM remains a challenge. We study nonconvex ERM, which takes the form of minimizing a finite-sum of…

Machine Learning · Computer Science 2023-02-03 Lingxiao Wang , Bargav Jayaraman , David Evans , Quanquan Gu

Stochastic variance reduced methods have gained a lot of interest recently for empirical risk minimization due to its appealing run time complexity. When the data size is large and disjointly stored on different machines, it becomes…

Machine Learning · Computer Science 2020-08-26 Shicong Cen , Huishuai Zhang , Yuejie Chi , Wei Chen , Tie-Yan Liu

We propose an optimization proxy in terms of iterative implicit gradient methods for solving constrained optimization problems with nonconvex loss functions. This framework can be applied to a broad range of machine learning settings,…

Optimization and Control · Mathematics 2025-10-14 Harshal D. Kaushik , Ming Jin

In this work, a classification method for SSVEP-based BCI is proposed. The classification method uses features extracted by traditional SSVEP-based BCI methods and finds optimal discrimination thresholds for each feature to classify the…

Signal Processing · Electrical Eng. & Systems 2019-07-25 Anti Ingel , Ilya Kuzovkin , Raul Vicente

Estimation of individualized treatment effects (ITE) from observational studies is a fundamental problem in causal inference and holds significant importance across domains, including healthcare. However, limited observational datasets pose…

Machine Learning · Computer Science 2024-02-14 Vinod Kumar Chauhan , Jiandong Zhou , Ghadeer Ghosheh , Soheila Molaei , David A. Clifton

Personalized medicine has received increasing attention among statisticians, computer scientists, and clinical practitioners. A major component of personalized medicine is the estimation of individualized treatment rules (ITRs). Recently,…

Methodology · Statistics 2015-08-14 Xin Zhou , Nicole Mayer-Hamblett , Umer Khan , Michael R. Kosorok

Using offline observational data for policy evaluation and learning allows decision-makers to evaluate and learn a policy that connects characteristics and interventions. Most existing literature has focused on either discrete treatment…

Artificial Intelligence · Computer Science 2025-01-22 Cheuk Hang Leung , Yiyan Huang , Yijun Li , Qi Wu

Recent advances in dynamic treatment regimes (DTRs) facilitate the search for optimal treatments, which are tailored to individuals' specific needs and able to maximize their expected clinical benefits. However, existing algorithms relying…

Machine Learning · Statistics 2024-10-18 Hanwen Ye , Wenzhuo Zhou , Ruoqing Zhu , Annie Qu

Evidence-based decision making often relies on meta-analyzing multiple studies, which enables more precise estimation and investigation of generalizability. Integrative analysis of multiple heterogeneous studies is, however, highly…

Methodology · Statistics 2020-09-15 Tianxi Cai , Molei Liu , Yin Xia

Precision medicine is a rapidly expanding area of health research wherein patient level information is used to inform treatment decisions. A statistical framework helps to formalize the individualization of treatment decisions that…

Methodology · Statistics 2021-12-23 Coraline Danieli , Erica Moodie

The field of precision medicine aims to tailor treatment based on patient-specific factors in a reproducible way. To this end, estimating an optimal individualized treatment regime (ITR) that recommends treatment decisions based on patient…

Nonconvex sparse learning plays an essential role in many areas, such as signal processing and deep network compression. Iterative hard thresholding (IHT) methods are the state-of-the-art for nonconvex sparse learning due to their…

Machine Learning · Computer Science 2021-01-05 Qianqian Tong , Guannan Liang , Tan Zhu , Jinbo Bi