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Related papers: ConnectomeBench: Can LLMs Proofread the Connectome…

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Producing connectomes from electron microscopy (EM) images has historically required a great deal of human proofreading effort. This manual annotation cost is the current bottleneck in scaling EM connectomics, for example, in making larger…

Computer Vision and Pattern Recognition · Computer Science 2025-10-01 Gary B Huang , William M Katz , Stuart Berg , Louis Scheffer

Automatic cell image segmentation methods in connectomics produce merge and split errors, which require correction through proofreading. Previous research has identified the visual search for these errors as the bottleneck in interactive…

Computer Vision and Pattern Recognition · Computer Science 2017-04-05 Daniel Haehn , Verena Kaynig , James Tompkin , Jeff W. Lichtman , Hanspeter Pfister

Large Language Models (LLMs) have demonstrated remarkable capabilities on general text; however, their proficiency in specialized scientific domains that require deep, interconnected knowledge remains largely uncharacterized. Metabolomics…

Computation and Language · Computer Science 2025-10-17 Yuxing Lu , Xukai Zhao , J. Ben Tamo , Micky C. Nnamdi , Rui Peng , Shuang Zeng , Xingyu Hu , Jinzhuo Wang , May D. Wang

Breakthroughs in frontier theory often depend on the combination of concrete diagrammatic notations with rigorous logic. While multimodal large language models (MLLMs) show promise in general scientific tasks, current benchmarks often focus…

Artificial Intelligence · Computer Science 2026-04-07 Zeyu Wang , Xiaogang Li , Peiyao Xiao , Qinhao Kong , Ben Wang , Chengliang Xu , Zichao Chen , Bing Zhao , Hu Wei

Phonology, the study of speech's structure and pronunciation rules, is a critical yet often overlooked component in Large Language Model (LLM) research. LLMs are widely used in various downstream applications that leverage phonology such as…

Computation and Language · Computer Science 2024-04-08 Ashima Suvarna , Harshita Khandelwal , Nanyun Peng

Automated building facade inspection is a critical component of urban resilience and smart city maintenance. Traditionally, this field has relied on specialized discriminative models (e.g., YOLO, Mask R-CNN) that excel at pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Hui Zhong , Yichun Gao , Luyan Liu , Hai Yang , Wang Wang , Haowei Zhang , Xinhu Zheng

Solving expert-level multimodal tasks is a key milestone towards general intelligence. As the capabilities of multimodal large language models (MLLMs) continue to improve, evaluation of such advanced multimodal intelligence becomes…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Yan Yang , Dongxu Li , Haoning Wu , Bei Chen , Liu Liu , Liyuan Pan , Junnan Li

Tractography is a unique method for mapping white matter connections in the brain, but tractography algorithms suffer from an inherent trade-off between sensitivity and specificity that limits accuracy. Incorporating prior knowledge of…

Computational Engineering, Finance, and Science · Computer Science 2025-11-10 Elinor Thompson , Tiantian He , Anna Schroder , Ahmed Abdulaal , Alec Sargood , Sonja Soskic , Henry F. J. Tregidgo , Daniel C. Alexander

Multimodal Large Language Models (MLLMs) have shown impressive capabilities in image understanding and generation. However, current benchmarks fail to accurately evaluate the chart comprehension of MLLMs due to limited chart types and…

Computer Vision and Pattern Recognition · Computer Science 2024-06-21 Zhengzhuo Xu , Sinan Du , Yiyan Qi , Chengjin Xu , Chun Yuan , Jian Guo

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

Large Language Models (LLMs) are increasingly deployed as scientific AI as- sistants, and a growing body of benchmarks evaluates their capabilities across knowledge retrieval, reasoning, code generation, and tool use. These evaluations,…

Multimodal Large Language Model (MLLM) relies on the powerful LLM to perform multimodal tasks, showing amazing emergent abilities in recent studies, such as writing poems based on an image. However, it is difficult for these case studies to…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Chaoyou Fu , Peixian Chen , Yunhang Shen , Yulei Qin , Mengdan Zhang , Xu Lin , Jinrui Yang , Xiawu Zheng , Ke Li , Xing Sun , Yunsheng Wu , Rongrong Ji , Caifeng Shan , Ran He

Multimodal LLMs (MLLMs) are capable of performing complex data analysis, visual question answering, generation, and reasoning tasks. However, their ability to analyze biometric data is relatively underexplored. In this work, we investigate…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Ekta Gavas , Sudipta Banerjee , Chinmay Hegde , Nasir Memon

The applications of large language models (LLMs) are promising for biomedical and healthcare research. Despite the availability of open-source LLMs trained using a wide range of biomedical data, current research on the applications of LLMs…

Machine Learning · Computer Science 2024-09-25 Tianyu Liu , Yijia Xiao , Xiao Luo , Hua Xu , W. Jim Zheng , Hongyu Zhao

Multimodal Large Language Models (MLLMs) have achieved significant advances in integrating visual and linguistic information, yet their ability to reason about complex and real-world scenarios remains limited. The existing benchmarks are…

Numerous theorems, such as those in geometry, are often presented in multimodal forms (e.g., diagrams). Humans benefit from visual reasoning in such settings, using diagrams to gain intuition and guide the proof process. Modern Multimodal…

Computation and Language · Computer Science 2025-06-09 Zhitao He , Zongwei Lyu , Dazhong Chen , Dadi Guo , Yi R. Fung

In contrast to their remarkable performance on general knowledge QA, the true abilities of Large Language Models (LLMs) in tasks demanding deep, specialized reasoning, such as in protein biology, have yet to be thoroughly investigated.…

Quantitative Methods · Quantitative Biology 2025-12-30 Dingyi Rong , Zijian Chen , Qi Jia , Kaiwei Zhang , Haotian Lu , Guangtao Zhai , Ning Liu

Large language models (LLMs) are increasingly being used for complex research tasks such as literature review, idea generation, and scientific paper analysis, yet their ability to truly understand and process the intricate relationships…

Computation and Language · Computer Science 2025-06-11 Shashidhar Reddy Javaji , Yupeng Cao , Haohang Li , Yangyang Yu , Nikhil Muralidhar , Zining Zhu

Can the rapid advances in code generation, function calling, and data analysis using large language models (LLMs) help automate the search and verification of hypotheses purely from a set of provided datasets? To evaluate this question, we…

Large language models (LLMs) have become increasingly pivotal across various domains, especially in handling complex data types. This includes structured data processing, as exemplified by ChartQA and ChatGPT-Ada, and multimodal…

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