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Related papers: sMRI-based Brain Age Estimation in MCI using Persi…

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The identification of Alzheimer's disease (AD) and its early stages using structural magnetic resonance imaging (MRI) has been attracting the attention of researchers. Various data-driven approaches have been introduced to capture subtle…

Artificial Intelligence · Computer Science 2021-08-11 Changhyun Park , Heung-Il Suk

This article introduces a predictor-dependent joint modeling framework for network data obtained from multiple subjects over a shared set of nodes with spatial co-ordinates and spatially correlated nodal attributes. The framework is highly…

Heterogeneity of brain diseases is a challenge for precision diagnosis/prognosis. We describe and validate Smile-GAN (SeMI-supervised cLustEring-Generative Adversarial Network), a novel semi-supervised deep-clustering method, which dissects…

Predicting whether someone with mild cognitive impairment (MCI) will progress to Alzheimer's disease (AD) is crucial in the early stages of neurodegeneration. This uncertainty limits enrollment in clinical trials and delays urgent…

Neurons and Cognition · Quantitative Biology 2026-03-30 Ishaan Cherukuri

Increased variability in performance has been associated with the emergence of several neurological and psychiatric pathologies. However, whether and how consistency of neuronal activity may also be indicative of an underlying pathology is…

Neurons and Cognition · Quantitative Biology 2014-10-31 J. H. Martínez , J. M. Pastor , P. Ariza , M. Zanin , D. Papo , F. Maestú , R. Bajo , S. Boccaletti , J. M. Buldú

Motivation: Characterising the changes in cortical morphology across the lifespan is fundamental for a range of research and clinical applications. Most studies to date have found a monotonic decrease in commonly used morphometrics, such as…

This study introduces a novel method for predicting cognitive age using psychophysiological tests. To determine cognitive age, subjects were asked to complete a series of psychological tests measuring various cognitive functions, including…

Neurons and Cognition · Quantitative Biology 2025-12-29 Daria D. Tyurina , Sergey V. Stasenko , Konstantin V. Lushnikov , Maria V. Vedunova

Structural MRI-to-amyloid PET synthesis has been proposed as a non-invasive alternative for amyloid assessment in Alzheimer's disease (AD). However, reported performance of identical models varies widely across studies, and increasingly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Louise E. G. Baron , Ross Callaghan , David M. Cash , Philip S. J. Weston , Hojjat Azadbakht , Hui Zhang

Alzheimer Disease poses a significant challenge, necessitating early detection for effective intervention. MRI is a key neuroimaging tool due to its ease of use and cost effectiveness. This study analyzes machine learning methods for MRI…

Neurons and Cognition · Quantitative Biology 2024-08-12 Alwani Liyana Ahmad , Jose Sanchez-Bornot , Roberto C. Sotero , Damien Coyle , Zamzuri Idris , Ibrahima Faye

Alzheimer's disease (AD) progresses through distinct stages, from early mild cognitive impairment (EMCI) to late mild cognitive impairment (LMCI) and eventually to AD. Accurate identification of these stages, especially distinguishing LMCI…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Aswini Kumar Patra , Soraisham Elizabeth Devi , Tejashwini Gajurel

In neuroimaging studies, the human cortex is commonly modeled as a sphere to preserve the topological structure of the cortical surface. Cortical neuroimaging measures hence can be modeled in spherical representation. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2018-12-20 Xinyang Feng , Jie Yang , Andrew F. Laine , Elsa D. Angelini

The deviation between chronological age and biological age is a well-recognized biomarker associated with cognitive decline and neurodegeneration. Age-related and pathology-driven changes to brain structure are captured by various…

Machine Learning · Computer Science 2022-11-01 Saurabh Sihag , Gonzalo Mateos , Corey McMillan , Alejandro Ribeiro

Purpose: Age biases have been identified as an essential factor in the diagnosis of ASD. The objective of this study was to compare the effect of different age groups in classifying ASD using morphological features (MF) and morphological…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Gokul Manoj , Sandeep Singh Sengar , Jac Fredo Agastinose Ronickom

Following the recent development of quantum machine learning techniques, the literature has reported several quantum machine learning algorithms for disease detection. This study explores the application of a hybrid quantum-classical…

Machine Learning · Computer Science 2024-05-06 Junggu Choi , Tak Hur , Daniel K. Park , Na-Young Shin , Seung-Koo Lee , Hakbae Lee , Sanghoon Han

How will my face look when I get older? Or, for a more challenging question: How will my brain look when I get older? To answer this question one must devise (and learn from data) a multivariate auto-regressive function which given an image…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Tian Xia , Agisilaos Chartsias , Chengjia Wang , Sotirios A. Tsaftaris

Deep Learning (DL) in neuroimaging has become increasingly relevant for detecting neurological conditions and neurodegenerative disorders. One of the most predominant biomarkers in neuroimaging is represented by brain age, which has been…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Carlo Alberto Barbano , Matteo Brunello , Benoit Dufumier , Marco Grangetto

Aging is a highly complex and heterogeneous process that progresses at different rates across individuals, making biological age (BA) a more accurate indicator of physiological decline than chronological age. While previous studies have…

Genomics · Quantitative Biology 2025-10-24 Huifa Li , Feilong Tang , Haochen Xue , Yulong Li , Xinlin Zhuang , Bin Zhang , Eran Segal , Imran Razzak

We present a novel topological framework for analyzing functional brain signals using time-frequency analysis. By integrating persistent homology with time-frequency representations, we capture multi-scale topological features that…

Neurons and Cognition · Quantitative Biology 2025-04-23 Moo K. Chung , Aaron F. Struck

Finding the underlying relationships among multiple imaging modalities in a coherent fashion is one of challenging problems in the multimodal analysis. In this study, we propose a novel multimodal network approach based on multidi-…

Quantitative Methods · Quantitative Biology 2016-02-26 Hyekyoung Lee , Hyejin Kang , Moo K. Chung , Seonhee Lim , Bung-Nyun Kim , Dong Soo Lee

Lesion detection in brain Magnetic Resonance Images (MRIs) remains a challenging task. MRIs are typically read and interpreted by domain experts, which is a tedious and time-consuming process. Recently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Marcel Bengs , Finn Behrendt , Max-Heinrich Laves , Julia Krüger , Roland Opfer , Alexander Schlaefer
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