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The application of deep learning to pathology assumes the existence of digital whole slide images of pathology slides. However, slide digitization is bottlenecked by the high cost of precise motor stages in slide scanners that are needed…

Image and Video Processing · Electrical Eng. & Systems 2020-11-13 Viswesh Krishna , Anirudh Joshi , Philip L. Bulterys , Eric Yang , Andrew Y. Ng , Pranav Rajpurkar

Backgr: Digital pathology images are increasingly used both for diagnosis and research, because slide scanners are nowadays broadly available and because the quantitative study of these images yields new insights in systems biology.…

Quantitative Methods · Quantitative Biology 2017-09-08 Christophe Deroulers , David Ameisen , Mathilde Badoual , Chloé Gerin , Alexandre Granier , Marc Lartaud

Computational methods on analyzing Whole Slide Images (WSIs) enable early diagnosis and treatments by supporting pathologists in detection and classification of tumors. However, the extremely high resolution of WSIs makes end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2026-03-18 Umar Marikkar , Muhammad Awais , Sara Atito

Objective: The exchange of health-related data is subject to regional laws and regulations, such as the General Data Protection Regulation (GDPR) in the EU or the Health Insurance Portability and Accountability Act (HIPAA) in the United…

Computers and Society · Computer Science 2024-01-24 Tom Bisson , Michael Franz , Isil Dogan O , Daniel Romberg , Christoph Jansen , Peter Hufnagl , Norman Zerbe

Advancing AI in computational pathology requires large, high-quality, and diverse datasets, yet existing public datasets are often limited in organ diversity, class coverage, or annotation quality. To bridge this gap, we introduce SPIDER…

Image and Video Processing · Electrical Eng. & Systems 2025-04-08 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

Whole slide imaging (WSI) has become the primary modality for digital pathology data. However, due to the size and high-resolution nature of these images, they are generally only accessed in smaller sections or tiles via specialized…

Quantitative Methods · Quantitative Biology 2022-07-07 Praphulla MS Bhawsar , Erich Bremer , Máire A Duggan , Stephen Chanock , Montserrat Garcia-Closas , Joel Saltz , Jonas S Almeida

Artificial intelligence (AI) is increasingly central to understanding how the brain processes information. However, the integration of neuroscience and modern AI is bottlenecked by a fragmented software ecosystem. Current tools are siloed…

Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 So Won Jeong , Veronika Ročková

Medical image analysis plays a key role in precision medicine as it allows the clinicians to identify anatomical abnormalities and it is routinely used in clinical assessment. Data curation and pre-processing of medical images are critical…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Sergey Primakov , Elizaveta Lavrova , Zohaib Salahuddin , Henry C Woodruff , Philippe Lambin

Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced pathologists. To reduce the workload and improve clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-06-28 Pingyi Chen , Honglin Li , Chenglu Zhu , Sunyi Zheng , Zhongyi Shui , Lin Yang

Whole slide imaging (WSI) refers to the digitization of a tissue specimen which enables pathologists to explore high-resolution images on a monitor rather than through a microscope. The formation of tissue folds occur during tissue…

Image and Video Processing · Electrical Eng. & Systems 2019-03-19 Morteza Babaie , H. R. Tizhoosh

A large amount of data is produced every second from modern information systems such as mobile devices, the world wide web, Internet of Things, social media, etc. Analysis and mining of this massive data requires a lot of advanced tools and…

Machine Learning · Computer Science 2020-01-13 Rising Odegua , Festus Ikpotokin

BrainLesion Suite is a versatile toolkit for building modular brain lesion image analysis pipelines in Python. Following Pythonic principles, BrainLesion Suite is designed to provide a 'brainless' development experience, minimizing…

Federated learning (FL) has emerged as a promising approach for collaborative medical image analysis, enabling multiple institutions to build robust predictive models while preserving sensitive patient data. In the context of Whole Slide…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Haolong Jin , Shenglin Liu , Cong Cong , Qingmin Feng , Yongzhi Liu , Lina Huang , Yingzi Hu

Automated data-driven modeling, the process of directly discovering the governing equations of a system from data, is increasingly being used across the scientific community. PySINDy is a Python package that provides tools for applying the…

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

The rapid growth of digital pathology and advances in self-supervised deep learning have enabled the development of foundational models for various pathology tasks across diverse diseases. While multimodal approaches integrating diverse…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Ekaterina Redekop , Mara Pleasure , Zichen Wang , Kimberly Flores , Anthony Sisk , William Speier , Corey W. Arnold

Pathological captioning of Whole Slide Images (WSIs), though is essential in computer-aided pathological diagnosis, has rarely been studied due to the limitations in datasets and model training efficacy. In this paper, we propose a new…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Wenkang Qin , Rui Xu , Peixiang Huang , Xiaomin Wu , Heyu Zhang , Lin Luo

Digital pathology offers a groundbreaking opportunity to transform clinical practice in histopathological image analysis, yet faces a significant hurdle: the substantial file sizes of pathological Whole Slide Images (WSI). While current…

Development of artificial intelligence (AI) for medical imaging demands curation and cleaning of large-scale clinical datasets comprising hundreds of thousands of images. Some modalities, such as mammography, contain highly standardized…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Arianna Bunnell , Kailee Hung , John A. Shepherd , Peter Sadowski
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