Related papers: Dynamic Residual Encoding with Slide-Level Contras…
Whole slide image (WSI) refers to a type of high-resolution scanned tissue image, which is extensively employed in computer-assisted diagnosis (CAD). The extremely high resolution and limited availability of region-level annotations make…
Background: The use of whole slide imaging (WSI) for digital pathology has recently been cleared for primary diagnosis in the US. A conventional WSI system scans the tissue slide to different positions and acquires the digital images. In a…
Lifelong learning for whole slide images (WSIs) poses the challenge of training a unified model to perform multiple WSI-related tasks, such as cancer subtyping and tumor classification, in a distributed, continual fashion. This is a…
Artificial Intelligence (AI) has great potential to improve health outcomes by training systems on vast digitized clinical datasets. Computational Pathology, with its massive amounts of microscopy image data and impact on diagnostics and…
Correct treatment of urothelial carcinoma patients is dependent on accurate grading and staging of the cancer tumour. This is determined manually by a pathologist by examining the histological whole-slide images (WSI). The large size of…
Whole Slide Image (WSI) MLLMs are difficult to build and deploy because gigapixel slides induce thousands of visual tokens, while only a small fraction of regions is diagnostically relevant. Existing slide-level pathology MLLMs typically…
Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…
Recent advancements in computational pathology have produced patch-level Multi-modal Large Language Models (MLLMs), but these models are limited by their inability to analyze whole slide images (WSIs) comprehensively and their tendency to…
High-dimensional neuroimaging analyses for clinical diagnosis are often constrained by compromises in spatiotemporal fidelity and by the limited adaptability of large-scale, general-purpose models. To address these challenges, we introduce…
Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…
Few-shot Whole Slide Image (WSI) classification is severely hampered by overfitting. We argue that this is not merely a data-scarcity issue but a fundamentally geometric problem. Grounded in the manifold hypothesis, our analysis shows that…
Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…
A key requirement for the success of supervised deep learning is a large labeled dataset - a condition that is difficult to meet in medical image analysis. Self-supervised learning (SSL) can help in this regard by providing a strategy to…
Digital histopathology whole slide images (WSIs) provide gigapixel-scale high-resolution images that are highly useful for disease diagnosis. However, digital histopathology image analysis faces significant challenges due to the limited…
We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…
Multiple instance learning (MIL) has been widely used for representing whole-slide pathology images. However, spatial, semantic, and decision entanglements among instances limit its representation and interpretability. To address these…
Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…
Convolutional Neural Networks (CNN) are state-of-the-art models for many image classification tasks. However, to recognize cancer subtypes automatically, training a CNN on gigapixel resolution Whole Slide Tissue Images (WSI) is currently…
Recently there have been many algorithms proposed for the classification of very high resolution whole slide images (WSIs). These new algorithms are mostly focused on finding novel ways to combine the information from small local patches…
In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…