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Reducing the radiation dose in computed tomography (CT) is important to mitigate radiation-induced risks. One option is to employ a well-trained model to compensate for incomplete information and map sparse-view measurements to the CT…
Multi-echo Gradient Echo (mGRE) sequences provide valuable quantitative parametric maps, such as Quantitative Susceptibility Mapping (QSM) and transverse relaxation rate (R2*), sensitive to tissue iron and myelin. However, structural…
Magnetic resonance imaging (MRI) is a widely used neuroimaging technique that can provide images of different contrasts (i.e., modalities). Fusing this multi-modal data has proven particularly effective for boosting model performance in…
Diffusion magnetic resonance imaging is a noninvasive imaging technique that can indirectly infer the microstructure of tissues and provide metrics which are subject to normal variability across subjects. Potentially abnormal values or…
Magnetic Resonance Imaging (MRI) is highly susceptible to motion artifacts due to the extended acquisition times required for k-space sampling. These artifacts can compromise diagnostic utility, particularly for dynamic imaging. We propose…
This study introduces a novel approach for image reconstruction based on a diffusion model conditioned on the native data domain. Our method is applied to multi-coil MRI and quantitative MRI reconstruction, leveraging the domain-conditioned…
Magnetic Resonance Imaging (MRI) is a powerful medical imaging modality, but unfortunately suffers from long scan times which, aside from increasing operational costs, can lead to image artifacts due to patient motion. Motion during the…
Generating realistic MRIs to accurately predict future changes in the structure of brain is an invaluable tool for clinicians in assessing clinical outcomes and analysing the disease progression at the patient level. However, current…
Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…
This dissertation is devoted to provide advanced nonconvex nonsmooth variational models of (Magnetic Resonance Image) MRI reconstruction, efficient learnable image reconstruction algorithms and parameter training algorithms that improve the…
Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…
Denoising diffusion models offer a promising approach to accelerating magnetic resonance imaging (MRI) and producing diagnostic-level images in an unsupervised manner. However, our study demonstrates that even tiny worst-case potential…
Supervised deep learning methods have shown promise in undersampled Magnetic Resonance Imaging (MRI) reconstruction, but their requirement for paired data limits their generalizability to the diverse MRI acquisition parameters. Recently,…
Diagnosing dementia, particularly for Alzheimer's Disease (AD) and frontotemporal dementia (FTD), is complex due to overlapping symptoms. While magnetic resonance imaging (MRI) and positron emission tomography (PET) data are critical for…
Synthesizing MR imaging sequences is highly relevant in clinical practice, as single sequences are often missing or are of poor quality (e.g. due to motion). Naturally, the idea arises that a target modality would benefit from multi-modal…
Portable low-field magnetic resonance imaging (MRI) systems have gained renewed interest owing to their cost effectiveness and point-of-care imaging capabilities. Yet, portable MRI systems suffer from relatively low signal-to-noise ratio…
Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…
Magnetic Resonance Imaging (MRI) plays a crucial role in brain disease diagnosis, but it is not always feasible for certain patients due to physical or clinical constraints. Recent studies attempt to synthesize MRI from Computed Tomography…
Diffusion MRI (dMRI) angular super-resolution (ASR) aims to reconstruct high-angular-resolution (HAR) signals from limited low-angular-resolution (LAR) data without prolonging scan time. However, existing methods are limited in recovering…
Purpose: Magnetic Resonance Imaging (MRI) enables non-invasive assessment of brain abnormalities during early life development. Permanent magnet scanners operating in the neonatal intensive care unit (NICU) facilitate MRI of sick infants,…