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Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Quantitative information on tumor heterogeneity and cell load could assist in designing effective and refined personalized treatment strategies. It was recently shown by us that such information can be inferred from the diffusion parameter…

Image and Video Processing · Electrical Eng. & Systems 2021-03-11 Yi Yin , Kai Breuhahn , Hans-Ulrich Kauczor , Oliver Sedlaczek , Irene E. Vignon-Clementel , Dirk Drasdo

Stroke is among the top three causes of death worldwide, and accurate identification of ischemic stroke lesion boundaries from imaging is critical for diagnosis and treatment. The main imaging modalities used include magnetic resonance…

Image and Video Processing · Electrical Eng. & Systems 2025-08-25 Juampablo E. Heras Rivera , Hitender Oswal , Tianyi Ren , Yutong Pan , William Henry , Caitlin M. Neher , Mehmet Kurt

Magnetic Resonance Imaging (MRI) is highly susceptible to motion artifacts due to the extended acquisition times required for k-space sampling. These artifacts can compromise diagnostic utility, particularly for dynamic imaging. We propose…

Image and Video Processing · Electrical Eng. & Systems 2025-07-04 Frederic Wang , Jonathan I. Tamir

Estimated brain age from magnetic resonance image (MRI) and its deviation from chronological age can provide early insights into potential neurodegenerative diseases, supporting early detection and implementation of prevention strategies.…

In MRI, variations in scan parameters, sequence, or hardware can lead to discrepancies in image appearance, even for the same subject. These inconsistencies, known as domain shifts, can hinder image analysis and degrade the performance of…

Image and Video Processing · Electrical Eng. & Systems 2026-05-05 Minjun Kim , Dong Ju Mun , Hwihun Jeong , Hangyeol Park , Haechang Lee , Se Young Chun , Jongho Lee

Surface-based cortical analysis is valuable for a variety of neuroimaging tasks, such as spatial normalization, parcellation, and gray matter (GM) thickness estimation. However, most tools for estimating cortical surfaces work exclusively…

This study introduces a novel approach for image reconstruction based on a diffusion model conditioned on the native data domain. Our method is applied to multi-coil MRI and quantitative MRI reconstruction, leveraging the domain-conditioned…

Machine Learning · Computer Science 2023-09-06 Wanyu Bian , Albert Jang , Fang Liu

Domain shift, the mismatch between training and testing data characteristics, causes significant degradation in the predictive performance in multi-source imaging scenarios. In medical imaging, the heterogeneity of population, scanners and…

Machine Learning · Computer Science 2021-12-21 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

AI algorithms have become valuable in aiding professionals in healthcare. The increasing confidence obtained by these models is helpful in critical decision demands. In clinical dermatology, classification models can detect malignant…

Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which pathological changes begin many years before the onset of clinical symptoms, making early detection essential for timely intervention. T1-weighted (T1w) Magnetic…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Jason Qiu

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

Deep learning holds immense promise for transforming medical image analysis, yet its clinical generalization remains profoundly limited. A major barrier is data heterogeneity. This is particularly true in Magnetic Resonance Imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Mehmet Yigit Avci , Pedro Borges , Virginia Fernandez , Paul Wright , Mehmet Yigitsoy , Sebastien Ourselin , Jorge Cardoso

We aim to leverage diffusion to address the challenging image matting task. However, the presence of high computational overhead and the inconsistency of noise sampling between the training and inference processes pose significant obstacles…

Computer Vision and Pattern Recognition · Computer Science 2024-12-05 Yihan Hu , Yiheng Lin , Wei Wang , Yao Zhao , Yunchao Wei , Humphrey Shi

Multispectral image analysis is a relatively promising field of research with applications in several areas, such as medical imaging and satellite monitoring. A considerable number of current methods of analysis are based on parametric…

Deep learning has been successful in predicting neurodegenerative disorders, such as Alzheimer's disease, from magnetic resonance imaging (MRI). Combining multiple imaging modalities, such as T1-weighted (T1) and diffusion-weighted imaging…

Artificial Intelligence · Computer Science 2026-01-30 Abhijith Shaji , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Greg Ver Steeg , Paul M. Thompson , Jose-Luis Ambite

Diffusion-weighted magnetic resonance imaging (DWI) and fiber tractography are the only methods to measure the structure of the white matter in the living human brain. The diffusion signal has been modelled as the combined contribution from…

Machine Learning · Statistics 2014-09-29 Charles Zheng , Franco Pestilli , Ariel Rokem

The biological behavior and treatment response of meningiomas depend on their grade, making an accurate diagnosis essential for treatment planning and prognosis assessment. We observed that the weighted fusion of spatial-frequency domain…

Computer Vision and Pattern Recognition · Computer Science 2026-02-17 Jiamiao Lu , Wei Wu , Ke Gao , Ping Mao , Weichuan Zhang , Tuo Wang , Lingkun Ma , Jiapan Guo , Zanyi Wu , Yuqing Hu , Changming Sun

Pooling publicly-available MRI data from multiple sites allows to assemble extensive groups of subjects, increase statistical power, and promote data reuse with machine learning techniques. The harmonization of multicenter data is necessary…

Machine Learning · Computer Science 2024-02-02 Chiara Marzi , Marco Giannelli , Andrea Barucci , Carlo Tessa , Mario Mascalchi , Stefano Diciotti

Collecting the large datasets needed to train deep neural networks can be very difficult, particularly for the many applications for which sharing and pooling data is complicated by practical, ethical, or legal concerns. However, it may be…