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We tackle biomedical image segmentation in the scenario of only a few labeled brain MR images. This is an important and challenging task in medical applications, where manual annotations are time-consuming. Current multi-atlas based…

Computer Vision and Pattern Recognition · Computer Science 2020-01-14 Hyeon Woo Lee , Mert R. Sabuncu , Adrian V. Dalca

3D medical image segmentation is a challenging task with crucial implications for disease diagnosis and treatment planning. Recent advances in deep learning have significantly enhanced fully supervised medical image segmentation. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Runmin Jiang , Zhaoxin Fan , Junhao Wu , Lenghan Zhu , Xin Huang , Tianyang Wang , Heng Huang , Min Xu

The need for labour intensive pixel-wise annotation is a major limitation of many fully supervised learning methods for segmenting bioimages that can contain numerous object instances with thin separations. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Peter Schuetz , Carola-Bibiane Schönlieb

Manual annotation of medical images is a labor-intensive and time-consuming process, posing a significant bottleneck in the development and deployment of robust medical imaging AI systems. This paper introduces a novel hands-free Human-AI…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yizhe Zhang

Intra-operative ultrasound is an increasingly important imaging modality in neurosurgery. However, manual interaction with imaging data during the procedures, for example to select landmarks or perform segmentation, is difficult and can be…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Julia Rackerseder , Rüdiger Göbl , Nassir Navab , Christoph Hennersperger

Segmentation is essential for medical image analysis tasks such as intervention planning, therapy guidance, diagnosis, treatment decisions. Deep learning is becoming increasingly prominent for segmentation, where the lack of annotations,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Zixuan Peng , Christine Tanner , Philipp Fuernstahl , Orcun Goksel

Medical Image Segmentation (MIS) includes diverse tasks, from bone to organ segmentation, each with its own challenges in finding the best segmentation model. The state-of-the-art AutoML-related MIS-framework nnU-Net automates many aspects…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Jannis Becktepe , Leona Hennig , Steffen Oeltze-Jafra , Marius Lindauer

Despite that deep learning has achieved state-of-the-art performance for medical image segmentation, its success relies on a large set of manually annotated images for training that are expensive to acquire. In this paper, we propose an…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Lu Wang , Dong Guo , Guotai Wang , Shaoting Zhang

Deep learning has brought the most profound contribution towards biomedical image segmentation to automate the process of delineation in medical imaging. To accomplish such task, the models are required to be trained using huge amount of…

Image and Video Processing · Electrical Eng. & Systems 2022-03-25 Narinder Singh Punn , Sonali Agarwal

Deep learning has achieved impressive results in nuclei segmentation, but the massive requirement for pixel-wise labels remains a significant challenge. To alleviate the annotation burden, existing methods generate pseudo masks for model…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Ziyue Wang , Ye Zhang , Yifeng Wang , Linghan Cai , Yongbing Zhang

Although the U-Net architecture has been extensively used for segmentation of medical images, we address two of its shortcomings in this work. Firstly, the accuracy of vanilla U-Net degrades when the target regions for segmentation exhibit…

Most state-of-the-art instance segmentation methods have to be trained on densely annotated images. While difficult in general, this requirement is especially daunting for biomedical images, where domain expertise is often required for…

Computer Vision and Pattern Recognition · Computer Science 2022-04-05 Adrian Wolny , Qin Yu , Constantin Pape , Anna Kreshuk

Current deep learning-based approaches for the segmentation of microscopy images heavily rely on large amount of training data with dense annotation, which is highly costly and laborious in practice. Compared to full annotation where the…

Computer Vision and Pattern Recognition · Computer Science 2023-12-11 Shijie Li , Mengwei Ren , Thomas Ach , Guido Gerig

Accurate segmentation of MR brain tissue is a crucial step for diagnosis,surgical planning, and treatment of brain abnormalities. However,it is a time-consuming task to be performed by medical experts. So, automatic and reliable…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Yang Deng , Yao Sun , Yongpei Zhu , Mingwang Zhu , Wei Han , Kehong Yuan

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Self-training has greatly facilitated domain adaptive semantic segmentation, which iteratively generates pseudo labels on unlabeled target data and retrains the network. However, realistic segmentation datasets are highly imbalanced, pseudo…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Binhui Xie , Longhui Yuan , Shuang Li , Chi Harold Liu , Xinjing Cheng

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-17 Shanshan Wang , Cheng Li , Rongpin Wang , Zaiyi Liu , Meiyun Wang , Hongna Tan , Yaping Wu , Xinfeng Liu , Hui Sun , Rui Yang , Xin Liu , Jie Chen , Huihui Zhou , Ismail Ben Ayed , Hairong Zheng

Semi-supervised learning, which leverages both annotated and unannotated data, is an efficient approach for medical image segmentation, where obtaining annotations for the whole dataset is time-consuming and costly. Traditional…

Computer Vision and Pattern Recognition · Computer Science 2025-02-06 Ruizhe Li , Grazziela Figueredo , Dorothee Auer , Rob Dineen , Paul Morgan , Xin Chen

Large-scale vision models like SAM have extensive visual knowledge, yet their general nature and computational demands limit their use in specialized tasks like medical image segmentation. In contrast, task-specific models such as U-Net++…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Yuchen Mao , Hongwei Li , Yinyi Lai , Giorgos Papanastasiou , Peng Qi , Yunjie Yang , Chengjia Wang

Instance segmentation is critical in biomedical imaging to accurately distinguish individual objects like cells, which often overlap and vary in size. Recent query-based methods, where object queries guide segmentation, have shown strong…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Yaroslav Prytula , Illia Tsiporenko , Ali Zeynalli , Dmytro Fishman