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In recent years, significant progress has been made in the medical image analysis domain using convolutional neural networks (CNNs). In particular, deep neural networks based on a U-shaped architecture (UNet) with skip connections have been…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Vamsi Krishna Vasa , Wenhui Zhu , Xiwen Chen , Peijie Qiu , Xuanzhao Dong , Yalin Wang

Foundational models, pretrained on a large scale, have demonstrated substantial success across non-medical domains. However, training these models typically requires large, comprehensive datasets, which contrasts with the smaller and more…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Raphael Schäfer , Till Nicke , Henning Höfener , Annkristin Lange , Dorit Merhof , Friedrich Feuerhake , Volkmar Schulz , Johannes Lotz , Fabian Kiessling

Automatic cell segmentation in microscopy images works well with the support of deep neural networks trained with full supervision. Collecting and annotating images, though, is not a sustainable solution for every new microscopy database…

Computer Vision and Pattern Recognition · Computer Science 2020-07-06 Youssef Dawoud , Julia Hornauer , Gustavo Carneiro , Vasileios Belagiannis

Recently, transfer learning and self-supervised learning have gained significant attention within the medical field due to their ability to mitigate the challenges posed by limited data availability, improve model generalisation, and reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Zehui Zhao , Laith Alzubaidi , Jinglan Zhang , Ye Duan , Usman Naseem , Yuantong Gu

Medical image segmentation annotations exhibit variations among experts due to the ambiguous boundaries of segmented objects and backgrounds in medical images. Although using multiple annotations for each image in the fully-supervised has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Shuai Wang , Tengjin Weng , Jingyi Wang , Yang Shen , Zhidong Zhao , Yixiu Liu , Pengfei Jiao , Zhiming Cheng , Yaqi Wang

Dynamic contrast-enhanced magnetic resonance imaging (DCE- MRI) is a widely used multi-phase technique routinely used in clinical practice. DCE and similar datasets of dynamic medical data tend to contain redundant information on the…

Due to the cross-domain distribution shift aroused from diverse medical imaging systems, many deep learning segmentation methods fail to perform well on unseen data, which limits their real-world applicability. Recent works have shown the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Shangqi Gao , Hangqi Zhou , Yibo Gao , Xiahai Zhuang

Advanced image segmentation and processing tools present an opportunity to study cell processes and their dynamics. However, image analysis is often routine and time-consuming. Nowadays, alternative data-driven approaches using deep…

Generalising deep models to new data from new centres (termed here domains) remains a challenge. This is largely attributed to shifts in data statistics (domain shifts) between source and unseen domains. Recently, gradient-based…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Xiao Liu , Spyridon Thermos , Alison O'Neil , Sotirios A. Tsaftaris

Medical image segmentation - the prerequisite of numerous clinical needs - has been significantly prospered by recent advances in convolutional neural networks (CNNs). However, it exhibits general limitations on modeling explicit long-range…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Yundong Zhang , Huiye Liu , Qiang Hu

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

The most popular networks used for cell segmentation (e.g. Cellpose, Stardist, HoverNet,...) rely on a prediction of a distance map. It yields unprecedented accuracy but hinges on fully annotated datasets. This is a serious limitation to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Clément Cazorla , Nathanaël Munier , Renaud Morin , Pierre Weiss

Medical experts often manually segment images to obtain diagnostic statistics and discard the resulting annotations. We aim to train segmentation models to alleviate this burden, but constrained to the retained summary statistics (e.g., the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-06 Omkar Kulkarni , Edward Raff , Tim Oates

Data scarcity is a major challenge in medical imaging, particularly for deep learning models. While data pooling (combining datasets from multiple sources) and data addition (adding more data from a new dataset) have been shown to enhance…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Ayush Roy , Samin Enam , Jun Xia , Won Hwa Kim , Vishnu Suresh Lokhande

Semi-supervised learning has the potential to improve the data-efficiency of training data-hungry deep neural networks, which is especially important for medical image analysis tasks where labeled data is scarce. In this work, we present a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Boon Peng Yap , Beng Koon Ng

While pre-training on object detection tasks, such as Common Objects in Contexts (COCO) [1], could significantly boost the performance of cell segmentation, it still consumes on massive fine-annotated cell images [2] with bounding boxes,…

Computer Vision and Pattern Recognition · Computer Science 2023-10-09 Weibin Liao , Xuhong Li , Qingzhong Wang , Yanwu Xu , Zhaozheng Yin , Haoyi Xiong

Segmentation is a crucial analysis task in biomedical imaging. Given the diverse experimental settings in this field, the lack of generalization limits the use of deep learning in practice. Domain adaptation is a promising remedy: it…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Anwai Archit , Constantin Pape

Recent advances have been made in applying convolutional neural networks to achieve more precise prediction results for medical image segmentation problems. However, the success of existing methods has highly relied on huge computational…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Dian Qin , Jiajun Bu , Zhe Liu , Xin Shen , Sheng Zhou , Jingjun Gu , Zhijua Wang , Lei Wu , Huifen Dai

Continual learning in medical image segmentation involves sequential data acquisition across diverse domains (e.g., clinical sites), where task interference between past and current domains often leads to catastrophic forgetting. Existing…

Image and Video Processing · Electrical Eng. & Systems 2025-07-08 Yuxin Ye , Yan Liu , Shujian Yu

Few-shot learning is a standard practice in most deep learning based histopathology image segmentation, given the relatively low number of digitized slides that are generally available. While many models have been developed for domain…

Image and Video Processing · Electrical Eng. & Systems 2021-10-01 Zheng Yuan , Andre Esteva , Ran Xu