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Parkinson's disease (PD) is a progressive neurodegenerative disorder that, in addition to directly impairing functional mobility, is frequently associated with vocal impairments such as hypophonia and dysarthria, which typically manifest in…

This paper presents the Standalone Neural ODE (sNODE), a continuous-depth neural ODE model capable of describing a full deep neural network. This uses a novel nonlinear conjugate gradient (NCG) descent optimization scheme for training,…

Machine Learning · Computer Science 2022-06-09 Rym Jaroudi , Lukáš Malý , Gabriel Eilertsen , B. Tomas Johansson , Jonas Unger , George Baravdish

This study presents the conditional neural fields for reduced-order modeling (CNF-ROM) framework to approximate solutions of parametrized partial differential equations (PDEs). The approach combines a parametric neural ODE (PNODE) for…

Numerical Analysis · Mathematics 2024-12-09 Minji Kim , Tianshu Wen , Kookjin Lee , Youngsoo Choi

Normative modeling is an emerging and promising approach to effectively study disorder heterogeneity in individual participants. In this study, we propose a novel normative modeling method by combining conditional variational autoencoder…

Machine Learning · Computer Science 2022-11-17 Xuetong Wang , Kanhao Zhao , Rong Zhou , Alex Leow , Ricardo Osorio , Yu Zhang , Lifang He

The stage and severity of Parkinson's disease (PD) is an important factor to consider for taking effective therapeutic decisions. Although the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) provides an…

Applications · Statistics 2018-05-30 R. Prashanth , Sumantra Dutta Roy

Spontaneous brain activity generically displays transient spatiotemporal coherent structures, which can selectively be affected in various neurological and psychiatric pathologies. Here we model the full brain's electroencephalographic…

Neurons and Cognition · Quantitative Biology 2025-02-25 Annalisa Caligiuri , David Papo , Görsev Yener , Bahar Güntekin , Tobias Galla , Lucas Lacasa , Massimiliano Zanin

Neural controlled differential equations (Neural CDEs) are a continuous-time extension of recurrent neural networks (RNNs), achieving state-of-the-art (SOTA) performance at modelling functions of irregular time series. In order to interpret…

Machine Learning · Computer Science 2021-06-22 James Morrill , Patrick Kidger , Lingyi Yang , Terry Lyons

Longitudinal neuroimaging is essential for modeling disease progression in Alzheimer's disease (AD), yet irregular sampling and missing visits pose substantial challenges for learning reliable temporal representations. To address this…

Machine Learning · Computer Science 2026-03-24 Ruiying Chen , Yutong Wang , Houliang Zhou , Wei Liang , Yong Chen , Lifang He

Neural decoding of pathological and physiological states can enable patient-individualized closed-loop neuromodulation therapy. Recent advances in pre-trained large-scale foundation models offer the potential for generalized state…

Deep learning holds tremendous potential in healthcare for uncovering hidden patterns within extensive clinical datasets, aiding in the diagnosis of various diseases. Parkinson's disease (PD) is a neurodegenerative condition characterized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-10 Aqib Nazir Mir , Iqra Nissar , Mumtaz Ahmed , Sarfaraz Masood , Danish Raza Rizvi

Generative modeling has evolved to a notable field of machine learning. Deep polynomial neural networks (PNNs) have demonstrated impressive results in unsupervised image generation, where the task is to map an input vector (i.e., noise) to…

Machine Learning · Computer Science 2021-10-29 Grigorios G Chrysos , Markos Georgopoulos , Yannis Panagakis

Neural ODEs (NODEs) are continuous-time neural networks (NNs) that can process data without the limitation of time intervals. They have advantages in learning and understanding the evolution of complex real dynamics. Many previous works…

Machine Learning · Computer Science 2024-11-05 Wenjie Mei , Dongzhe Zheng , Shihua Li

Parkinson's Disease(PD) is one of the major nervous system disorders that affect people over 60. PD can cause cognitive impairments. In this work, we explore various approaches to identify Parkinson's using Magnetic Resonance (MR) T1 images…

Image and Video Processing · Electrical Eng. & Systems 2020-07-03 Tahjid Ashfaque Mostafa , Irene Cheng

We develop a novel deep learning technique, termed Deep Orthogonal Decomposition (DOD), for dimensionality reduction and reduced order modeling of parameter dependent partial differential equations. The approach consists in the construction…

Numerical Analysis · Mathematics 2024-05-15 Nicola Rares Franco , Andrea Manzoni , Paolo Zunino , Jan S. Hesthaven

In the past few years, there are several researches on Parkinson's disease (PD) recognition using single-photon emission computed tomography (SPECT) images with deep learning (DL) approach. However, the DL model's complexity usually results…

Image and Video Processing · Electrical Eng. & Systems 2021-05-05 Theerasarn Pianpanit , Sermkiat Lolak , Phattarapong Sawangjai , Thapanun Sudhawiyangkul , Theerawit Wilaiprasitporn

Neural ordinary differential equations (NODEs) presented a new paradigm to construct (continuous-time) neural networks. While showing several good characteristics in terms of the number of parameters and the flexibility in constructing…

Machine Learning · Computer Science 2021-06-01 Sheo Yon Jhin , Minju Jo , Taeyong Kong , Jinsung Jeon , Noseong Park

Operator learning has emerged as a promising paradigm for developing efficient surrogate models to solve partial differential equations (PDEs). However, existing approaches often overlook the domain knowledge inherent in the underlying PDEs…

Machine Learning · Computer Science 2025-10-20 Ziqian Li , Kang Liu , Yongcun Song , Hangrui Yue , Enrique Zuazua

Many physical processes such as weather phenomena or fluid mechanics are governed by partial differential equations (PDEs). Modelling such dynamical systems using Neural Networks is an active research field. However, current methods are…

Machine Learning · Computer Science 2022-10-12 Andrzej Dulny , Andreas Hotho , Anna Krause

In this thesis the aim is to work on optimizing the modern machine learning models for personalized forecasting of Alzheimer Disease (AD) Progression from clinical trial data. The data comes from the TADPOLE challenge, which is one of the…

Machine Learning · Computer Science 2020-08-07 Aritra Banerjee

Parkinson's disease assessment has garnered growing interest in recent years, particularly with the advent of sensor data and machine learning techniques. Among these, multimodal approaches have demonstrated strong performance by…

Artificial Intelligence · Computer Science 2025-11-05 Minlin Zeng , Zhipeng Zhou , Yang Qiu , Martin J. McKeown , Zhiqi Shen