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Two-directional beam-tracking (2DBT) is a method for phase-contrast imaging and tomography that uses an intensity modulator to structure the X-ray beam into an array of independent circular beamlets that are resolved by a high-resolution…

Dark-field X-ray imaging visualizes structural inhomogeneities through small-angle scattering, but existing directional methods are confined to the micrometer scale. While recent advances have extended dark-field capabilities to nanoscale…

X-ray dark-field imaging creates a representation of the sample where contrast is generated by subresolution features within the volume under inspection. These are detected by a local measurement of the radiation field's angular…

X-ray micro tomography is a non-destructive, three-dimensional inspection technique applied across a vast range of fields and disciplines, ranging from research to industrial, encompassing engineering, biology and medical research.…

Directional dark-field imaging is an emerging x-ray modality that is sensitive to unresolved anisotropic scattering from sub-pixel sample microstructures. A single-grid imaging set-up can be used to capture dark-field images by looking at…

Image and Video Processing · Electrical Eng. & Systems 2023-04-07 Michelle K Croughan , Ying Ying How , Allan Pennings , Kaye S Morgan

We propose an imaging system and methodology for mapping soft-tissue samples in three dimensions, with micron-scale and isotropic spatial resolution, with low-concentrations as well as in the absence of heavy metal staining. We used hard…

Instrumentation and Detectors · Physics 2023-12-21 Michela Esposito , Nicole Schieber , Alessandro Olivo , Yannick Schwab , Marco Endrizzi

X-ray dark-field or ultra-small angle scatter imaging has become increasingly important since the introduction of phase-based x-ray imaging and is having transformative impact in fields such as in vivo lung imaging and explosives detection.…

Dark-field images are formed by small-angle scattering of x-ray photons. The small-angle scattering signal is particularly sensitive to structural variations and density fluctuation on a length scale of several ten to hundred nanometers,…

Medical Physics · Physics 2010-03-11 W. Cong , F. Pfeiffer , M. Bech , O. Bunk , C. David , G. Wang

In recent years, a novel x-ray imaging modality has emerged that reveals unresolved sample microstructure via a "dark-field image", which provides complementary information to conventional "bright-field" images, such as attenuation and…

Anisotropic X-ray Dark-Field Tomography (AXDT) is a novel imaging technology that enables the extraction of fiber structures on the micrometer scale, far smaller than standard X-ray Computed Tomography (CT) setups. Directional and…

Computational Engineering, Finance, and Science · Computer Science 2025-01-07 David Frank , Cederik Höfs , Tobias Lasser

The dark-field signal uncovers details beyond conventional X-ray attenuation contrast, which is especially valuable for material sciences. In particular, dark-field techniques are able to reveal structures beyond the spatial resolution of a…

Anisotropic X-ray Dark-field Tomography (AXDT) is a recently developed imaging modality that enables the visualization of oriented microstructures using lab-based X-ray grating interferometer setups. While there are very promising…

Medical Physics · Physics 2022-07-04 Theodor Cheslerean-Boghiu , Franz Pfeiffer , Tobias Lasser

Based on high-throughput dark-field full-field optical coherence tomography, we designed and built an OCT system that can measure a variety of samples with different scattered light intensities, such as materials with multi-layer…

Optics · Physics 2024-01-30 Youlong Fan , Qingye Hu , Zhongping Wang , Xiantao Wei , Zengming Zhang

Phase Contrast Imaging (PCI), Dark-Field (DF) and Directional Dark-Field (DDF) imaging are recent X-ray imaging modalities that have demonstrated their interest by providing access to information and contrasts different from those provided…

Image and Video Processing · Electrical Eng. & Systems 2023-04-25 Clara Magnin , Laurene Quenot , Sylvain Bohic , Dan Mihai Cenda , Manuel Fernández Martínez , Blandine Lantz , Bertrand Faure , Emmanuel Brun

Biophotonics is an active research area in molecular imaging, genetic diagnosis and prognosis, with direct applicability in precision medicine. However, long-standing challenges of biophotonics are well known due to low signal-to-noise…

Medical Physics · Physics 2017-10-02 Michael C Lun , Wei Zhang , Yue Zhao , Jeffrey Anker , Wenxiang Cong , Ge Wang , Changqing Li

Dark-field radiography is a novel X-ray imaging modality that enables complementary diagnostic information by visualizing the microstructural properties of lung tissue. Implemented via a Talbot-Lau interferometer integrated into a…

Talbot(-Lau) interferometric X-ray darkfield imaging has, over the past decade, gained substantial interest for its ability to provide insights into a sample's microstructure below the imaging resolution by means of ultra small angle…

Applied Physics · Physics 2021-02-01 Jonas Graetz , Andreas Balles , Randolf Hanke , Simon Zabler

X-ray dark-field imaging enables a spatially-resolved visualization of ultra-small-angle X-ray scattering. Using phantom measurements, we demonstrate that a material's effective dark-field signal may be reduced by modification of the…

The size of the smallest detectable sample feature in an x-ray imaging system is usually restricted by the spatial resolution of the system. This limitation can now be overcome using the diffusive dark-field signal, which is generated by…

Medical Physics · Physics 2024-02-01 Ying Ying How , David M. Paganin , Kaye S. Morgan

X-ray microtomography is a powerful non-destructive technique allowing 3D virtual histology of resected human tissue. The achievable imaging field-of-view, is however limited by the fixed number of detector elements, enforcing the…

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