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Continual Test-Time Adaptation (CTTA) aims to adapt a pretrained model to ever-changing environments during the test time under continuous domain shifts. Most existing CTTA approaches are based on the Mean Teacher (MT) structure, which…

Machine Learning · Computer Science 2024-07-03 Jiaxu Tian , Fan Lyu

The recent global surge in COVID-19 infections has been fueled by new SARS-CoV-2 variants, namely Alpha, Beta, Gamma, Delta, etc. The molecular mechanism underlying such surge is elusive due to 4,653 non-degenerate mutations on the spike…

Biomolecules · Quantitative Biology 2021-09-13 Rui Wang , Jiahui Chen , Yuta Hozumi , Changchuan Yin , Guo-Wei Wei

Due to their substantial sizes, large language models (LLMs) are typically deployed within a single-backbone multi-tenant framework. In this setup, a single instance of an LLM backbone must cater to multiple users or tasks through the…

Computation and Language · Computer Science 2024-09-27 Tianfang Xie , Tianjing Li , Wei Zhu , Wei Han , Yi Zhao

Controlled table-to-text generation seeks to generate natural language descriptions for highlighted subparts of a table. Previous SOTA systems still employ a sequence-to-sequence generation method, which merely captures the table as a…

Computation and Language · Computer Science 2022-05-10 Fei Wang , Zhewei Xu , Pedro Szekely , Muhao Chen

Sequential tabular data is one of the most commonly used data types in real-world applications. Different from conventional tabular data, where rows in a table are independent, sequential tabular data contains rich contextual and sequential…

The goal of text ranking is to generate an ordered list of texts retrieved from a corpus in response to a query. Although the most common formulation of text ranking is search, instances of the task can also be found in many natural…

Information Retrieval · Computer Science 2021-08-20 Jimmy Lin , Rodrigo Nogueira , Andrew Yates

Multiple Sequence Alignment (MSA) plays a pivotal role in unveiling the evolutionary trajectories of protein families. The accuracy of protein structure predictions is often compromised for protein sequences that lack sufficient homologous…

Biomolecules · Quantitative Biology 2024-10-29 Bo Chen , Zhilei Bei , Xingyi Cheng , Pan Li , Jie Tang , Le Song

Many proteins remain functionally unannotated. Sequence alignment (SA) uncovers missing annotations by transferring functional knowledge between species' sequence-conserved regions. Because SA is imperfect, network alignment (NA)…

Molecular Networks · Quantitative Biology 2020-06-16 Shawn Gu , Tijana Milenkovic

Parameter Efficient Fine-Tuning (PEFT) is a key technique for adapting a large pretrained model to downstream tasks by fine-tuning only a small number of parameters. Recent methods based on Fourier transforms have further reduced the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Baoquan Zhang , Zhehao Yu , Lisai Zhang , Kenghong Lin , Tianran Chen , Yuxi Sun , Yunming Ye , Yao He

Recent work using pretrained transformers has shown impressive performance when fine-tuned with data from the downstream problem of interest. However, they struggle to retain that performance when the data characteristics changes. In this…

Machine Learning · Computer Science 2023-11-30 Martin Wistuba , Prabhu Teja Sivaprasad , Lukas Balles , Giovanni Zappella

Following the successful application of vision transformers in multiple computer vision tasks, these models have drawn the attention of the signal processing community. This is because signals are often represented as spectrograms (e.g.…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Nicolae-Catalin Ristea , Radu Tudor Ionescu , Fahad Shahbaz Khan

The importance of understanding SARS-CoV-2 evolution cannot be overemphasized. Recent studies confirm that natural selection is the dominating mechanism of SARS-CoV-2 evolution, which favors mutations that strengthen viral infectivity. We…

Populations and Evolution · Quantitative Biology 2021-10-12 Rui Wang , Jiahui Chen , Guo-Wei Wei

The growing adoption of electronic health record (EHR) systems has provided unprecedented opportunities for predictive modeling to guide clinical decision making. Structured EHRs contain longitudinal observations of patients across hospital…

Machine Learning · Computer Science 2026-03-12 Deyi Li , Zijun Yao , Qi Xu , Muxuan Liang , Lingyao Li , Zijian Xu , Mei Liu

Integrating histopathology with spatial transcriptomics (ST) provides a powerful opportunity to link tissue morphology with molecular function. Yet most existing multimodal approaches rely on a small set of highly variable genes, which…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Sejuti Majumder , Saarthak Kapse , Moinak Bhattacharya , Xuan Xu , Alisa Yurovsky , Prateek Prasanna

Parameter-efficient fine-tuning (PEFT) techniques such as low-rank adaptation (LoRA) can effectively adapt large pre-trained foundation models to downstream tasks using only a small fraction (0.1%-10%) of the original trainable weights. An…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Samar Khanna , Medhanie Irgau , David B. Lobell , Stefano Ermon

Parameter-efficient transfer learning (PETL) methods have emerged as a solid alternative to the standard full fine-tuning approach. They only train a few extra parameters for each downstream task, without sacrificing performance and…

Audio and Speech Processing · Electrical Eng. & Systems 2024-07-16 Umberto Cappellazzo , Daniele Falavigna , Alessio Brutti , Mirco Ravanelli

Evolutionary computing, particularly genetic algorithm (GA), is a combinatorial optimization method inspired by natural selection and the transmission of genetic information, which is widely used to identify optimal solutions to complex…

Neural and Evolutionary Computing · Computer Science 2024-12-31 Shanqing Yu , Meng Zhou , Jintao Zhou , Minghao Zhao , Yidan Song , Yao Lu , Zeyu Wang , Qi Xuan

A pipeline to evaluate the evolution of viral dynamics based on a new model-driven approach has been developed in the present study. The proposed methods exploit real data and the multiscale structure of the infection dynamics to provide…

Populations and Evolution · Quantitative Biology 2025-11-25 Andrea Bondesan , Antonio Piralla , Elena Ballante , Antonino Maria Guglielmo Pitrolo , Silvia Figini , Fausto Baldanti , Mattia Zanella

Traditional image registration methods are robust but slow due to their iterative nature. While deep learning has accelerated inference, it often struggles with domain shifts. Emerging registration foundation models offer a balance of speed…

Computer Vision and Pattern Recognition · Computer Science 2026-02-02 Lin Chen , Yue He , Fengting Zhang , Yaonan Wang , Fengming Lin , Xiang Chen , Min Liu

Accurate forecasting of renewable energy generation is fundamental to enhancing the dynamic performance of modern power grids, especially under high renewable penetration. This paper presents Channel-Time Patch Time-Series Transformer…

Machine Learning · Computer Science 2026-01-23 Kuan Lu , Menghao Huo , Yuxiao Li , Qiang Zhu , Zhenrui Chen
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