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Survival analysis, as a challenging task, requires integrating Whole Slide Images (WSIs) and genomic data for comprehensive decision-making. There are two main challenges in this task: significant heterogeneity and complex inter- and…
We introduce Matched Machine Learning, a framework that combines the flexibility of machine learning black boxes with the interpretability of matching, a longstanding tool in observational causal inference. Interpretability is paramount in…
Weighted model integration (WMI) extends weighted model counting (WMC) in providing a computational abstraction for probabilistic inference in mixed discrete-continuous domains. WMC has emerged as an assembly language for state-of-the-art…
To tackle interpretability in deep learning, we present a novel framework to jointly learn a predictive model and its associated interpretation model. The interpreter provides both local and global interpretability about the predictive…
Rapid progress in machine learning and deep learning has enabled a wide range of applications in the electricity load forecasting of power systems, for instance, univariate and multivariate short-term load forecasting. Though the strong…
Sentence embeddings are central to modern NLP and AI systems, yet little is known about their internal structure. While we can compare these embeddings using measures such as cosine similarity, the contributing features are not…
Bayesian neural networks with latent variables are scalable and flexible probabilistic models: They account for uncertainty in the estimation of the network weights and, by making use of latent variables, can capture complex noise patterns…
A key barrier to interpreting large language models is polysemanticity, where neurons activate for multiple unrelated concepts. Sparse autoencoders (SAEs) have been proposed to mitigate this issue by transforming dense activations into…
Deep learning has achieved remarkable success across many domains, but it has also created a growing demand for interpretability in model predictions. Although many explainable machine learning methods have been proposed, post-hoc…
Brain decoding is a popular multivariate approach for hypothesis testing in neuroimaging. It is well known that the brain maps derived from weights of linear classifiers are hard to interpret because of high correlations between predictors,…
It is well-known in the field of lossless data compression that probabilistic next-symbol prediction can be used to compress sequences of symbols. Deep neural networks are able to capture rich dependencies in data, offering a powerful means…
While deep learning offers powerful capabilities for scientific research, its application is often hindered by a lack of quantitative reliability. To address this, we introduce a probabilistic denoising framework that simultaneously…
Large Language Models (LLMs) have achieved unprecedented breakthroughs in various natural language processing domains. However, the enigmatic ``black-box'' nature of LLMs remains a significant challenge for interpretability, hampering…
Interpretation of deep learning remains a very challenging problem. Although the Class Activation Map (CAM) is widely used to interpret deep model predictions by highlighting object location, it fails to provide insight into the salient…
Diffusion probabilistic models (DPMs) have achieved remarkable quality in image generation that rivals GANs'. But unlike GANs, DPMs use a set of latent variables that lack semantic meaning and cannot serve as a useful representation for…
Integrating heterogeneous biomedical data including imaging, omics, and clinical records supports accurate diagnosis and personalised care. Graph-based models fuse such non-Euclidean data by capturing spatial and relational structure, yet…
Precision cancer medicine aims to determine the optimal treatment for each patient. In-vitro cancer drug sensitivity screens combined with multi-omics characterization of the cancer cells have become an important tool to achieve this aim.…
The DEDICOM algorithm provides a uniquely interpretable matrix factorization method for symmetric and asymmetric square matrices. We employ a new row-stochastic variation of DEDICOM on the pointwise mutual information matrices of text…
Translating potential disease biomarkers between multi-species 'omics' experiments is a new direction in biomedical research. The existing methods are limited to simple experimental setups such as basic healthy-diseased comparisons. Most of…
Recent work has demonstrated that complex visual stimuli can be decoded from human brain activity using deep generative models, offering new ways to probe how the brain represents real-world scenes. However, many existing approaches first…