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Motivated by the need for advanced solutions in the segmentation and inpainting of glioma-affected brain regions in multi-modal magnetic resonance imaging (MRI), this study presents an integrated approach leveraging the strengths of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-17 Ramy A. Zeineldin , Franziska Mathis-Ullrich

Purpose: Large Language Models (LLMs) like GPT (Generative Pre-trained Transformer) from OpenAI and LLaMA (Large Language Model Meta AI) from Meta AI are increasingly recognized for their potential in the field of cheminformatics,…

Biomolecules · Quantitative Biology 2024-05-22 Shaghayegh Sadeghi , Alan Bui , Ali Forooghi , Jianguo Lu , Alioune Ngom

Large-scale vision-language models (VLMs), such as CLIP, have achieved remarkable success in zero-shot learning (ZSL) by leveraging large-scale visual-text pair datasets. However, these methods often lack interpretability, as they compute…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Shiming Chen , Bowen Duan , Salman Khan , Fahad Shahbaz Khan

Large language models (LLMs) have demonstrated remarkable success in NLP tasks. However, there is a paucity of studies that attempt to evaluate their performances on social media-based health-related natural language processing tasks, which…

Computation and Language · Computer Science 2024-03-29 Yuting Guo , Anthony Ovadje , Mohammed Ali Al-Garadi , Abeed Sarker

Thematic analysis provides valuable insights into participants' experiences through coding and theme development, but its resource-intensive nature limits its use in large healthcare studies. Large language models (LLMs) can analyze text at…

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

This paper explores the image-sharing capability of Large Language Models (LLMs), such as GPT-4 and LLaMA 2, in a zero-shot setting. To facilitate a comprehensive evaluation of LLMs, we introduce the PhotoChat++ dataset, which includes…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Young-Jun Lee , Dokyong Lee , Joo Won Sung , Jonghwan Hyeon , Ho-Jin Choi

The emergence of Small Language Models (SLMs) as privacy-preserving alternatives for sensitive applications raises a fundamental question about their inherent understanding capabilities compared to Large Language Models (LLMs). This paper…

Computation and Language · Computer Science 2025-07-15 Hong Jia , Shiya Fu , Feng Xia , Vassilis Kostakos , Ting Dang

Glioma constitutes 80% of malignant primary brain tumors and is usually classified as HGG and LGG. The LGG tumors are less aggressive, with slower growth rate as compared to HGG, and are responsive to therapy. Tumor biopsy being challenging…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Subhashis Banerjee , Sushmita Mitra , Francesco Masulli , Stefano Rovetta

Large language models (LLMs) have emerged as transformative tools in medicine, with strong capabilities in language understanding, reasoning, and structured information extraction. Radiation oncology is particularly well suited for LLM…

In radiology, Artificial Intelligence (AI) has significantly advanced report generation, but automatic evaluation of these AI-produced reports remains challenging. Current metrics, such as Conventional Natural Language Generation (NLG) and…

Computation and Language · Computer Science 2024-02-20 Qingqing Zhu , Xiuying Chen , Qiao Jin , Benjamin Hou , Tejas Sudharshan Mathai , Pritam Mukherjee , Xin Gao , Ronald M Summers , Zhiyong Lu

Multi-modal large language models (MLLMs), such as GPT-4o, excel at integrating text and visual data but face systematic challenges when interpreting ambiguous or incomplete visual stimuli. This study leverages statistical modeling to…

Machine Learning · Computer Science 2024-12-09 Ching-Yi Wang

Recent advancements in deep learning have driven significant progress in lossless image compression. With the emergence of Large Language Models (LLMs), preliminary attempts have been made to leverage the extensive prior knowledge embedded…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Junhao Du , Chuqin Zhou , Ning Cao , Gang Chen , Yunuo Chen , Zhengxue Cheng , Li Song , Guo Lu , Wenjun Zhang

We study idiom-based visual puns--images that align an idiom's literal and figurative meanings--and present an iterative framework that coordinates a large language model (LLM), a text-to-image model (T2IM), and a multimodal LLM (MLLM) for…

Computation and Language · Computer Science 2025-12-01 Kelaiti Xiao , Liang Yang , Dongyu Zhang , Paerhati Tulajiang , Hongfei Lin

Vision-language models (VLMs) have gained significant attention in computational pathology due to their multimodal learning capabilities that enhance big-data analytics of giga-pixel whole slide image (WSI). However, their sensitivity to…

Computer Vision and Pattern Recognition · Computer Science 2025-05-02 Vasudev Sharma , Ahmed Alagha , Abdelhakim Khellaf , Vincent Quoc-Huy Trinh , Mahdi S. Hosseini

Registration of pre-operative and post-recurrence brain images is often needed to evaluate the effectiveness of brain gliomas treatment. While recent deep learning-based deformable registration methods have achieved remarkable success with…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Tony C. W. Mok , Albert C. S. Chung

Histology analysis of the tumor micro-environment integrated with genomic assays is the gold standard for most cancers in modern medicine. This paper proposes a Gene-induced Multimodal Pre-training (GiMP) framework, which jointly…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Ting Jin , Xingran Xie , Renjie Wan , Qingli Li , Yan Wang

Contrastive visual language pretraining has emerged as a powerful method for either training new language-aware image encoders or augmenting existing pretrained models with zero-shot visual recognition capabilities. However, existing works…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Ming Y. Lu , Bowen Chen , Andrew Zhang , Drew F. K. Williamson , Richard J. Chen , Tong Ding , Long Phi Le , Yung-Sung Chuang , Faisal Mahmood

There is growing interest in systems that generate captions for scientific figures. However, assessing these systems output poses a significant challenge. Human evaluation requires academic expertise and is costly, while automatic…

Computation and Language · Computer Science 2023-10-25 Ting-Yao Hsu , Chieh-Yang Huang , Ryan Rossi , Sungchul Kim , C. Lee Giles , Ting-Hao K. Huang

Controllable pathology image synthesis requires reliable regulation of spatial layout, tissue morphology, and semantic detail. However, existing text-guided diffusion models offer only coarse global control and lack the ability to enforce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Yuntao Shou , Xiangyong Cao , Qian Zhao , Deyu Meng
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