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Frequency dependent selection and demographic fluctuations play important roles in evolutionary and ecological processes. Under frequency dependent selection, the average fitness of the population may increase or decrease based on…

Populations and Evolution · Quantitative Biology 2015-06-23 Weini Huang , Christoph Hauert , Arne Traulsen

When polygenic traits are under stabilizing selection, many different combinations of alleles allow close adaptation to the optimum. If alleles have equal effects, all combinations that result in the same deviation from the optimum are…

Populations and Evolution · Quantitative Biology 2014-04-04 Harold P. de Vladar , Nick Barton

We updated the agent based Monte Carlo code HERITAGE that simulates human evolution within restrictive environments such as interstellar, sub-light speed spacecraft in order to include the effects of population genetics. We incorporated a…

Popular Physics · Physics 2021-02-03 F. Marin , C. Beluffi , F. Fischer

A steady influx of a single deleterious multilocus genotype will impose genetic load on the resident population and leave multiple descendants carrying various numbers of the foreign alleles. Provided that the foreign types are rare at…

Populations and Evolution · Quantitative Biology 2015-06-16 Alexey Yanchukov , Stephen R. Proulx

We examine birth--death processes with state dependent transition probabilities and at least one absorbing boundary. In evolution, this describes selection acting on two different types in a finite population where reproductive events occur…

Populations and Evolution · Quantitative Biology 2010-10-12 Philipp M. Altrock , Chaytanya S. Gokhale , Arne Traulsen

We consider a stochastic individual-based model for the evolution of a haploid, asexually reproducing population. The space of possible traits is given by the vertices of a (possibly directed) finite graph $G=(V,E)$. The evolution of the…

Probability · Mathematics 2020-03-10 Loren Coquille , Anna Kraut , Charline Smadi

We consider the accumulation of beneficial and deleterious mutations in large asexual populations. The rate of adaptation is affected by the total mutation rate, proportion of beneficial mutations and population size $N$. We show that…

Probability · Mathematics 2010-10-18 Feng Yu , Alison Etheridge , Charles Cuthbertson

We study the dynamics of a population subject to selective pressures, evolving either on RNA neutral networks or in toy fitness landscapes. We discuss the spread and the neutrality of the population in the steady state. Different limits…

Populations and Evolution · Quantitative Biology 2009-11-13 Sumedha , Olivier C Martin , Luca Peliti

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

Probability · Mathematics 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi

Gene drive alleles bias their own inheritance to offspring. They can fix in a wild-type population in spite of a fitness cost, and even lead to the eradication of the target population if the fitness cost is high. However, this outcome may…

Populations and Evolution · Quantitative Biology 2026-04-30 Léna Kläy , Léo Girardin , Florence Débarre , Vincent Calvez

In ecology and population dynamics, gene-flow refers to the transfer of a trait from one population to another. This phenomenon appears in studying the evolution of social features, such as languages. From the mathematical point of view,…

Optimization and Control · Mathematics 2021-10-22 Idriss Mazari , Domenec Ruiz-Balet , Enrique Zuazua

The accumulation of beneficial mutations on many competing genetic backgrounds in rapidly adapting populations has a striking impact on evolutionary dynamics. This effect, known as clonal interference, causes erratic fluctuations in the…

Populations and Evolution · Quantitative Biology 2013-05-31 Katya Kosheleva , Michael Desai

Evolution on neutral networks of genotypes has been found in models to concentrate on genotypes with high mutational robustness, to a degree determined by the topology of the network. Here analysis is generalized beyond neutral networks to…

Populations and Evolution · Quantitative Biology 2015-09-01 Lee Altenberg

The adaptive evolution of large asexual populations is generally characterized by competition between clones carrying different beneficial mutations. This interference phenomenon slows down the adaptation speed and makes the theoretical…

Populations and Evolution · Quantitative Biology 2012-12-20 Maria Rita Fumagalli , Matteo Osella , Philippe Thomen , Francois Heslot , Marco Cosentino Lagomarsino

Stronger selection implies faster evolution---that is, the greater the force, the faster the change. This apparently self-evident proposition, however, is derived under the assumption that genetic variation within a population is primarily…

Populations and Evolution · Quantitative Biology 2017-08-18 Masahiko Ueda , Nobuto Takeuchi , Kunihiko Kaneko

We consider a stochastic model for an evolving population. We show that in the presence of genotype extinctions the population dies out for a low mutation probability but may survive for a high mutation probability. This turns upside down…

Populations and Evolution · Quantitative Biology 2014-10-24 Rinaldo B. Schinazi

We consider birth-and-death stochastic evolution of genotypes with different lengths. The genotypes might mutate that provides a stochastic changing of lengthes by a free diffusion law. The birth and death rates are length dependent which…

Populations and Evolution · Quantitative Biology 2015-06-16 Dmitri Finkelshtein , Yuri Kondratiev , Oleksandr Kutoviy , Stanislav Molchanov , Elena Zhizhina

The strong Allee effect plays an important role on the evolution of population in ecological systems. One important concept is the Allee threshold that determines the persistence or extinction of the population in a long time. In general, a…

Analysis of PDEs · Mathematics 2024-08-05 Fanze Kong , Juncheng Wei

Clonal interference, competition between multiple co-occurring beneficial mutations, has a major role in adaptation of asexual populations. We provide a simple individual based stochastic model of clonal interference taking into account a…

Probability · Mathematics 2015-05-19 Sylvain Billiard , Charline Smadi

We consider a stochastic model for the evolution of a discrete population structured by a trait with values on a finite grid of the torus, and with mutation and selection. Traits are vertically inherited unless a mutation occurs, and…

Probability · Mathematics 2022-06-17 Nicolas Champagnat , Sylvie Méléard , Sepideh Mirrahimi , Viet Chi Tran