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Related papers: A Roadmap for Predictive Human Immunology

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The immune system is a highly parallel and distributed intelligent system which has learning, memory, and associative capabilities. Artificial Immune System is an evolutionary paradigm inspired by the biological aspects of the immune system…

Cryptography and Security · Computer Science 2011-02-22 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

The adaptive immune system is a natural diagnostic and therapeutic. It recognizes threats earlier than clinical symptoms manifest and neutralizes antigen with exquisite specificity. Recognition specificity and broad reactivity is enabled…

Quantitative Methods · Quantitative Biology 2019-07-26 Alex J. Brown , Igor Snapkov , Rahmad Akbar , Milena Pavlović , Enkelejda Miho , Geir K. Sandve , Victor Greiff

Natural Immune system plays a vital role in the survival of the all living being. It provides a mechanism to defend itself from external predates making it consistent systems, capable of adapting itself for survival incase of changes. The…

Artificial Intelligence · Computer Science 2011-03-11 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

Artificial intelligence and machine learning are reshaping how we approach scientific discovery, not by replacing established methods but by extending what researchers can probe, predict, and design. In this roadmap we provide a…

The human immune system has numerous properties that make it ripe for exploitation in the computational domain, such as robustness and fault tolerance, and many different algorithms, collectively termed Artificial Immune Systems (AIS), have…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Amanda Whitbrook , Uwe Aickelin

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self-cells or non-self cells. It does this with the help…

Artificial Intelligence · Computer Science 2010-07-05 Uwe Aickelin , Dipankar Dasgupta

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self-cells or non-self cells. It does this with the help…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Dipankar Dasgupta

Human-AI coevolution, defined as a process in which humans and AI algorithms continuously influence each other, increasingly characterises our society, but is understudied in artificial intelligence and complexity science literature.…

Innate immunity now occupies a central role in immunology. However, artificial immune system models have largely been inspired by adaptive not innate immunity. This paper reviews the biological principles and properties of innate immunity…

Artificial Intelligence · Computer Science 2010-07-05 Jamie Twycross , Uwe Aickelin

In the past, the development of vaccines and immunotherapeutics relied heavily on trial-and-error experimentation and extensive in vivo testing, often requiring years of pre-clinical and clinical trials. Today, artificial intelligence (AI)…

Artificial Intelligence · Computer Science 2025-06-17 Elhoucine Elfatimi , Yassir Lekbach , Swayam Prakash , Lbachir BenMohamed

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self or non-self substances. It does this with the help of…

Neural and Evolutionary Computing · Computer Science 2013-08-26 Uwe Aickelin , Dipankar Dasgupta , Feng Gu

Artificial immune system can be used to generate schedules in changing environments and it has been proven to be more robust than schedules developed using a genetic algorithm. Good schedules can be produced especially when the number of…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Edmund Burke , Aniza Din

Over the last few years, more and more heuristic decision making techniques have been inspired by nature, e.g. evolutionary algorithms, ant colony optimisation and simulated annealing. More recently, a novel computational intelligence…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin

The immune system is a cognitive system of complexity comparable to the brain and its computational algorithms suggest new solutions to engineering problems or new ways of looking at these problems. Using immunological principles, a two (or…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 P. J. Costa Branco , J. A. Dente , R. Vilela Mendes

We introduce the fundamental ideas and challenges of Predictable AI, a nascent research area that explores the ways in which we can anticipate key validity indicators (e.g., performance, safety) of present and future AI ecosystems. We argue…

An adaptive agent predicting the future state of an environment must weigh trust in new observations against prior experiences. In this light, we propose a view of the adaptive immune system as a dynamic Bayesian machinery that updates its…

Populations and Evolution · Quantitative Biology 2019-05-14 Andreas Mayer , Vijay Balasubramanian , Aleksandra M. Walczak , Thierry Mora

The use of artificial immune systems in intrusion detection is an appealing concept for two reasons. Firstly, the human immune system provides the human body with a high level of protection from invading pathogens, in a robust,…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Jungwon Kim , Peter J. Bentley , Uwe Aickelin , Julie Greensmith , Gianni Tedesco , Jamie Twycross

Interactive AI systems increasingly employ a human-in-the-loop strategy. This creates new challenges for the HCI community when designing such systems. We reveal and investigate some of these challenges in a case study with an industry…

Human-Computer Interaction · Computer Science 2022-07-27 Changkun Ou , Daniel Buschek , Sven Mayer , Andreas Butz

Since the turn of the millennium, computational modelling of biological systems has evolved remarkably and sees matured use spanning basic and clinical research. While the topic of the peri-millennial debate about the virtues and…

Quantitative Methods · Quantitative Biology 2025-08-05 Axel Loewe , Peter J. Hunter , Peter Kohl

The immune system can be thought as a complex network of different interacting elements. A cellular automaton, defined in shape-space, was recently shown to exhibit self-regulation and complex behavior and is, therefore, a good candidate to…

Statistical Mechanics · Physics 2009-10-31 Rita Maria Zorzenon dos Santos , Americo T. Bernardes
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