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Missing input sequences are common in medical imaging data, posing a challenge for deep learning models reliant on complete input data. In this work, inspired by MultiMAE [2], we develop a masked autoencoder (MAE) paradigm for multi-modal,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Ayhan Can Erdur , Christian Beischl , Daniel Scholz , Jiazhen Pan , Benedikt Wiestler , Daniel Rueckert , Jan C Peeken

Recent learning-based approaches have made astonishing advances in calibrated medical imaging like computerized tomography (CT), yet they struggle to generalize in uncalibrated modalities -- notably magnetic resonance (MR) imaging, where…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Peirong Liu , Oula Puonti , Xiaoling Hu , Karthik Gopinath , Annabel Sorby-Adams , Daniel C. Alexander , W. Taylor Kimberly , Juan E. Iglesias

Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data. Here we show that a single self-supervised representation can…

Machine Learning · Computer Science 2026-05-27 Yizhou Wu , Shansong Wang , Yuheng Li , Mojtaba Safari , Mingzhe Hu , Chih-Wei Chang , Harini Veeraraghavan , Xiaofeng Yang

Models for segmentation of brain lesions in multi-modal MRI are commonly trained for a specific pathology using a single database with a predefined set of MRI modalities, determined by a protocol for the specific disease. This work explores…

Segmentation models are important tools for the detection and analysis of lesions in brain MRI. Depending on the type of brain pathology that is imaged, MRI scanners can acquire multiple, different image modalities (contrasts). Most…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Anthony P. Addison , Felix Wagner , Wentian Xu , Natalie Voets , Konstantinos Kamnitsas

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents an even more difficult scenario. To cope with this challenge,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-16 Tianyi Liu , Zhaorui Tan , Haochuan Jiang , Xi Yang , Kaizhu Huang

Brain lesion segmentation plays an essential role in neurological research and diagnosis. As brain lesions can be caused by various pathological alterations, different types of brain lesions tend to manifest with different characteristics…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Xinru Zhang , Ni Ou , Berke Doga Basaran , Marco Visentin , Mengyun Qiao , Renyang Gu , Cheng Ouyang , Yaou Liu , Paul M. Matthew , Chuyang Ye , Wenjia Bai

Traditional brain lesion segmentation models for multi-modal MRI are typically tailored to specific pathologies, relying on datasets with predefined modalities. Adapting to new MRI modalities or pathologies often requires training separate…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Yousef Sadegheih , Pratibha Kumari , Dorit Merhof

We propose a unified deep meta-learning framework for accelerated magnetic resonance imaging (MRI) that jointly addresses multi-coil reconstruction and cross-modality synthesis. Motivated by the limitations of conventional methods in…

Optimization and Control · Mathematics 2026-03-10 Merham Fouladvand , Peuroly Batra

Brain tumor segmentation is often based on multiple magnetic resonance imaging (MRI). However, in clinical practice, certain modalities of MRI may be missing, which presents a more difficult scenario. To cope with this challenge, Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Tianyi Liu , Zhaorui Tan , Muyin Chen , Xi Yang , Haochuan Jiang , Kaizhu Huang

Multimodal MRI offers complementary information for brain tumor segmentation, but clinical scans often lack one or more modalities, which degrades segmentation performance. In this paper, we propose UniME (Uni-Encoder Meets Multi-Encoders),…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Peibo Song , Xiaotian Xue , Jinshuo Zhang , Zihao Wang , Jinhua Liu , Shujun Fu , Fangxun Bao , Si Yong Yeo

Multimodal magnetic resonance imaging (MRI) constitutes the first line of investigation for clinicians in the care of brain tumors, providing crucial insights for surgery planning, treatment monitoring, and biomarker identification.…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Lucas Robinet , Ahmad Berjaoui , Elizabeth Cohen-Jonathan Moyal

The field of computer vision is undergoing a paradigm shift toward large-scale foundation model pre-training via self-supervised learning (SSL). Leveraging large volumes of unlabeled brain MRI data, such models can learn anatomical priors…

Image and Video Processing · Electrical Eng. & Systems 2026-01-15 Petros Koutsouvelis , Matej Gazda , Leroy Volmer , Sina Amirrajab , Kamil Barbierik , Branislav Setlak , Jakub Gazda , Peter Drotar

Brain Tumor Segmentation from magnetic resonance imaging (MRI) is a critical technique for early diagnosis. However, rather than having complete four modalities as in BraTS dataset, it is common to have missing modalities in clinical…

Computer Vision and Pattern Recognition · Computer Science 2019-04-17 Yan Shen , Mingchen Gao

Magnetic Resonance Imaging (MRI) is a widely used imaging technique to assess brain tumor. Accurately segmenting brain tumor from MR images is the key to clinical diagnostics and treatment planning. In addition, multi-modal MR images can…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

Multimodal MRI provides complementary and clinically relevant information to probe tissue condition and to characterize various diseases. However, it is often difficult to acquire sufficiently many modalities from the same subject due to…

Image and Video Processing · Electrical Eng. & Systems 2021-06-08 Xiaofeng Liu , Fangxu Xing , Georges El Fakhri , Jonghye Woo

Reliable anomaly detection in brain MRI remains challenging due to the scarcity of annotated abnormal cases and the frequent absence of key imaging modalities in real clinical workflows. Existing single-class or multi-class anomaly…

Computer Vision and Pattern Recognition · Computer Science 2025-12-25 Changwei Wu , Yifei Chen , Yuxin Du , Mingxuan Liu , Jinying Zong , Beining Wu , Jie Dong , Feiwei Qin , Yunkang Cao , Qiyuan Tian

Resting-state functional magnetic resonance imaging (rs-fMRI) can reflect spontaneous neural activities in brain and is widely used for brain disorder analysis.Previous studies propose to extract fMRI representations through diverse…

Quantitative Methods · Quantitative Biology 2023-06-27 Qianqian Wang , Wei Wang , Yuqi Fang , P. -T. Yap , Hongtu Zhu , Hong-Jun Li , Lishan Qiao , Mingxia Liu

Accurate brain tumor segmentation from Magnetic Resonance Imaging (MRI) is desirable to joint learning of multimodal images. However, in clinical practice, it is not always possible to acquire a complete set of MRIs, and the problem of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-05 Yao Zhang , Nanjun He , Jiawei Yang , Yuexiang Li , Dong Wei , Yawen Huang , Yang Zhang , Zhiqiang He , Yefeng Zheng

Multimodal MRI is essential for brain tumor segmentation, yet missing modalities in clinical practice cause existing methods to exhibit >40% performance variance across modality combinations, rendering them clinically unreliable. We propose…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Chengxiang Guo , Jian Wang , Junhua Fei , Xiao Li , Chunling Chen , Yun Jin
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