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Related papers: PLUTO-4: Frontier Pathology Foundation Models

200 papers

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Computational pathology needs whole-slide image (WSI) foundation models that transfer across diverse clinical tasks, yet current approaches remain largely slide-centric, often depend on private data and expensive paired-report supervision,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Yousef Kotp , Vincent Quoc-Huy Trinh , Christopher Pal , Mahdi S. Hosseini

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot

Foundation models are reshaping computational pathology by enabling transfer learning, where models pre-trained on vast datasets can be adapted for downstream diagnostic, prognostic, and therapeutic response tasks. Despite these advances,…

Computational pathology, which involves analyzing whole slide images for automated cancer diagnosis, relies on multiple instance learning, where performance depends heavily on the feature extractor and aggregator. Recent Pathology…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Conghao Xiong , Hao Chen , Joseph J. Y. Sung

Pathology foundation models (PFMs) have recently emerged as powerful pretrained encoders for computational pathology, enabling transfer learning across a wide range of downstream tasks. However, systematic comparisons of these models for…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Fredrik K. Gustafsson , Constance Boissin , Johan Vallon-Christersson , David A. Clifton , Mattias Rantalainen

Computational pathology foundation models (CPathFMs) have emerged as a powerful approach for analyzing histopathological data, leveraging self-supervised learning to extract robust feature representations from unlabeled whole-slide images.…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Dong Li , Guihong Wan , Xintao Wu , Xinyu Wu , Ajit J. Nirmal , Christine G. Lian , Peter K. Sorger , Yevgeniy R. Semenov , Chen Zhao

Foundation models have shown strong performance in multi-object segmentation with visual prompts, yet histopathology images remain challenging due to high cellular density, heterogeneity, and the gap between pixel-level supervision and…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yonghuang Wu , Wenwen Zeng , Xuan Xie , Chengqian Zhao , Guoqing Wu , Jinhua Yu

Recent advances in digital pathology have demonstrated the effectiveness of foundation models across diverse applications. In this report, we present Atlas, a novel vision foundation model based on the RudolfV approach. Our model was…

Foundation models are rapidly being developed for computational pathology applications. However, it remains an open question which factors are most important for downstream performance with data scale and diversity, model size, and training…

Foundation models offer a promising route to transferable remote sensing representations, but many current approaches depend on very large pretraining datasets and fixed sensor configurations, limiting their suitability for ecological and…

Pathology, the microscopic examination of diseased tissue, is critical for diagnosing various medical conditions, particularly cancers. Traditional methods are labor-intensive and prone to human error. Digital pathology, which converts…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Dmitry Nechaev , Alexey Pchelnikov , Ekaterina Ivanova

The emergence of pathology foundation models has revolutionized computational histopathology, enabling highly accurate, generalized whole-slide image analysis for improved cancer diagnosis, and prognosis assessment. While these models show…

Purpose: This study provides the first comprehensive evaluation of foundation models in fetal ultrasound (US) imaging under low inter-class variability conditions. While recent vision foundation models such as DINOv3 have shown remarkable…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Edoardo Conti , Riccardo Rosati , Lorenzo Federici , Adriano Mancini , Maria Chiara Fiorentin

We present PLUTO, a powerful framework that pushes the limit of imitation learning-based planning for autonomous driving. Our improvements stem from three pivotal aspects: a longitudinal-lateral aware model architecture that enables…

Robotics · Computer Science 2024-04-23 Jie Cheng , Yingbing Chen , Qifeng Chen

Biomedical Foundation Models (FMs) are rapidly transforming AI-enabled healthcare research and entering clinical validation. However, their susceptibility to learning non-biological technical features -- including variations in…

Photoplethysmography (PPG)-based foundation models are gaining traction due to the widespread use of PPG in biosignal monitoring and their potential to generalize across diverse health applications. In this paper, we introduce Pulse-PPG,…

Machine Learning · Computer Science 2025-07-25 Mithun Saha , Maxwell A. Xu , Wanting Mao , Sameer Neupane , James M. Rehg , Santosh Kumar

Despite the promise of computational pathology foundation models, adapting them to specific clinical tasks remains challenging due to the complexity of whole-slide image (WSI) processing, the opacity of learned features, and the wide range…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Abdul Rahman Diab , Emily E. Karn , Renchin Wu , Emily S. Ruiz , William Lotter

The use of artificial intelligence to enable precision medicine and decision support systems through the analysis of pathology images has the potential to revolutionize the diagnosis and treatment of cancer. Such applications will depend on…