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Biological synaptic transmission is unreliable, and this unreliability likely degrades neural circuit performance. While there are biophysical mechanisms that can increase reliability, for instance by increasing vesicle release probability,…

Neurons and Cognition · Quantitative Biology 2024-07-02 James Malkin , Cian O'Donnell , Conor Houghton , Laurence Aitchison

We study the asymptotic behaviour of widely used tests for evaluating and comparing predictive accuracy when forecast errors exhibit heavy tails. In particular, when loss differentials have infinite variance, the Diebold-Mariano test…

Methodology · Statistics 2026-05-20 Jonas F. Frederiksen , Muneya Matsui , Rasmus S. Pedersen

Exposure bias is a well-known issue in recommender systems where the exposure is not fairly distributed among items in the recommendation results. This is especially problematic when bias is amplified over time as a few items (e.g., popular…

Information Retrieval · Computer Science 2023-09-06 Masoud Mansoury , Bamshad Mobasher

Machine learning models for continuous outcomes often yield systematically biased predictions, particularly for values that largely deviate from the mean. Specifically, predictions for large-valued outcomes tend to be negatively biased…

Machine Learning · Statistics 2024-09-05 Hwiyoung Lee , Shuo Chen

A classic trade-off that school districts face when deciding which matching algorithm to use is that it is not possible to always respect both priorities and preferences. The student-proposing deferred acceptance algorithm (DA) respects…

Theoretical Economics · Economics 2024-09-20 Estelle Cantillon , Li Chen , Juan S. Pereyra

In adaptive clinical trials, the conventional end-of-trial point estimate of a treatment effect is prone to bias, that is, a systematic tendency to deviate from its true value. As stated in recent FDA guidance on adaptive designs, it is…

Noise in data appears to be inevitable in most real-world machine learning applications and would cause severe overfitting problems. Not only can data features contain noise, but labels are also prone to be noisy due to human input. In this…

Machine Learning · Computer Science 2025-05-09 Weipeng Huang , Qin Li , Yang Xiao , Cheng Qiao , Tie Cai , Junwei Liang , Neil J. Hurley , Guangyuan Piao

A default assumption in reinforcement learning (RL) and optimal control is that observations arrive at discrete time points on a fixed clock cycle. Yet, many applications involve continuous-time systems where the time discretization, in…

Machine Learning · Computer Science 2024-01-17 Zichen Zhang , Johannes Kirschner , Junxi Zhang , Francesco Zanini , Alex Ayoub , Masood Dehghan , Dale Schuurmans

The switchback is an experimental design that measures treatment effects by repeatedly turning an intervention on and off for a whole system. Switchback experiments are a robust way to overcome cross-unit spillover effects; however, they…

Methodology · Statistics 2025-12-16 Yuchen Hu , Stefan Wager

Changes in parameters of a physical device can eventually lead to catastrophic failure. This paper discusses a parameter estimation method based on synchronization between a model and time series data. In particular, we examine the…

chao-dyn · Physics 2007-05-23 Justin Goodwin , Reggie Brown , Lutz Junge

We derive a trade-off relation between the accuracy of implementing a desired unitary evolution using a restricted set of free unitaries and the size of the assisting system, in terms of the resource generating/losing capacity of the target…

Quantum Physics · Physics 2020-02-14 Ryuji Takagi , Hiroyasu Tajima

A reinforcement learning agent tries to maximize its cumulative payoff by interacting in an unknown environment. It is important for the agent to explore suboptimal actions as well as to pick actions with highest known rewards. Yet, in…

Machine Learning · Computer Science 2019-01-23 Reazul Hasan Russel

When cells measure concentrations of chemical signals, they may average multiple measurements over time in order to reduce noise in their measurements. However, when cells are in a environment that changes over time, past measurements may…

Cell Behavior · Quantitative Biology 2025-03-05 Aparajita Kashyap , Wei Wang , Brian A. Camley

The main challenge of multiagent reinforcement learning is the difficulty of learning useful policies in the presence of other simultaneously learning agents whose changing behaviors jointly affect the environment's transition and reward…

Most positive and unlabeled data is subject to selection biases. The labeled examples can, for example, be selected from the positive set because they are easier to obtain or more obviously positive. This paper investigates how learning can…

Machine Learning · Computer Science 2019-07-01 Jessa Bekker , Pieter Robberechts , Jesse Davis

The ground truth used for training image, video, or speech quality prediction models is based on the Mean Opinion Scores (MOS) obtained from subjective experiments. Usually, it is necessary to conduct multiple experiments, mostly with…

Audio and Speech Processing · Electrical Eng. & Systems 2021-12-15 Gabriel Mittag , Saman Zadtootaghaj , Thilo Michael , Babak Naderi , Sebastian Möller

Gradient-based methods for optimisation of objectives in stochastic settings with unknown or intractable dynamics require estimators of derivatives. We derive an objective that, under automatic differentiation, produces low-variance…

Machine Learning · Computer Science 2019-09-25 Gregory Farquhar , Shimon Whiteson , Jakob Foerster

Selective classification is a powerful tool for automated decision-making in high-risk scenarios, allowing classifiers to act only when confident and abstain when uncertainty is high. Given a target accuracy, our goal is to minimize…

Statistics Theory · Mathematics 2025-10-28 Mohamed Ndaoud , Peter Radchenko , Bradley Rava

It is standard practice in online retail to run pricing experiments by randomizing at the article-level, i.e. by changing prices of different products to identify treatment effects. Due to customers' cross-price substitution behavior, such…

Applications · Statistics 2024-02-23 Lars Roemheld , Justin Rao

As learning difficulty is crucial for machine learning (e.g., difficulty-based weighting learning strategies), previous literature has proposed a number of learning difficulty measures. However, no comprehensive investigation for learning…

Machine Learning · Computer Science 2022-09-20 Weiyao Zhu , Ou Wu , Fengguang Su , Yingjun Deng
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