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Aligned Large Language Models (LLMs) showcase remarkable versatility, capable of handling diverse real-world tasks. Meanwhile, aligned LLMs are also expected to exhibit speciality, excelling in specific applications. However, fine-tuning…

Computation and Language · Computer Science 2025-02-25 Hengyuan Zhang , Yanru Wu , Dawei Li , Sak Yang , Rui Zhao , Yong Jiang , Fei Tan

The combination of multimodal Vision-Language Models (VLMs) and Large Language Models (LLMs) opens up new possibilities for medical classification. This work offers a rigorous, unified benchmark by using four publicly available datasets…

Artificial Intelligence · Computer Science 2026-01-26 Meet Raval , Tejul Pandit , Dhvani Upadhyay

Multi-modal Large Language Models (MLLMs) integrate visual and linguistic reasoning to address complex tasks such as image captioning and visual question answering. While MLLMs demonstrate remarkable versatility, MLLMs appears limited…

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Foundation models have emerged as a powerful tool for many AI problems. Despite the tremendous success of foundation models, effective adaptation to new tasks, particularly those with limited labels, remains an open question and lacks…

Machine Learning · Computer Science 2024-02-26 Zhuoyan Xu , Zhenmei Shi , Junyi Wei , Fangzhou Mu , Yin Li , Yingyu Liang

In-context learning (ICL) enables medical image segmentation models to adapt to new anatomical structures from limited examples, reducing the clinical annotation burden. However, standard ICL methods typically rely on dense, global…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 T. Camaret Ndir , Marco Reisert , Robin T. Schirrmeister

While large language models (LLMs) have become the de facto framework for literature-related tasks, they still struggle to function as domain-specific literature agents due to their inability to connect pieces of knowledge and reason across…

Digital Libraries · Computer Science 2026-03-03 Andreas Varvarigos , Ali Maatouk , Jiasheng Zhang , Ngoc Bui , Jialin Chen , Leandros Tassiulas , Rex Ying

Large language models (LLMs) operate in two fundamental learning modes - fine-tuning (FT) and in-context learning (ICL) - raising key questions about which mode yields greater language proficiency and whether they differ in their inductive…

Computation and Language · Computer Science 2026-05-19 Bishwamittra Ghosh , Soumi Das , Till Speicher , Qinyuan Wu , Mohammad Aflah Khan , Deepak Garg , Krishna P. Gummadi , Evimaria Terzi

Vision-language models (VLMs) achieve remarkable success in single-image tasks. However, real-world scenarios often involve intricate multi-image inputs, leading to a notable performance decline as models struggle to disentangle critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Juntian Zhang , Chuanqi cheng , Yuhan Liu , Wei Liu , Jian Luan , Rui Yan

Automated knowledge curation for biomedical ontologies is key to ensure that they remain comprehensive, high-quality and up-to-date. In the era of foundational language models, this study compares and analyzes three NLP paradigms for…

Machine Learning · Computer Science 2023-12-21 Emily Groves , Minhong Wang , Yusuf Abdulle , Holger Kunz , Jason Hoelscher-Obermaier , Ronin Wu , Honghan Wu

State-of-the-art Vision-Language Models (VLMs) ground the vision and the language modality primarily via projecting the vision tokens from the encoder to language-like tokens, which are directly fed to the Large Language Model (LLM)…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Sivan Doveh , Shaked Perek , M. Jehanzeb Mirza , Wei Lin , Amit Alfassy , Assaf Arbelle , Shimon Ullman , Leonid Karlinsky

Recent advancements in training paradigms for Large Language Models (LLMs) have unlocked their remarkable capabilities in natural language processing and cross-domain generalization. While LLMs excel in tasks like programming and…

Machine Learning · Computer Science 2025-10-01 Yuan Huang

Large Language Models (LLMs), being generic task solvers, are versatile. However, despite the vast amount of data they are trained on, there are speculations about their adaptation capabilities to a new domain. Additionally, the simple…

Computation and Language · Computer Science 2025-09-03 Anum Afzal , Mehul Kumawat , Florian Matthes

Recent advances in microscopy have enabled the rapid generation of terabytes of image data in cell biology and biomedical research. Vision-language models (VLMs) offer a promising solution for large-scale biological image analysis,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-03 Alejandro Lozano , Jeffrey Nirschl , James Burgess , Sanket Rajan Gupte , Yuhui Zhang , Alyssa Unell , Serena Yeung-Levy

Large models such as Large Language Models (LLMs) and Vision Language Models (VLMs) have transformed artificial intelligence, powering applications in natural language processing, computer vision, and multimodal learning. However, fully…

The pervasive deployment of Large Language Models-LLMs in various sectors often neglects the nuanced requirements of individuals and small organizations, who benefit more from models precisely tailored to their specific business contexts…

Computation and Language · Computer Science 2024-07-10 Jiaxi Cui , Wentao Zhang , Jing Tang , Xudong Tong , Zhenwei Zhang , Amie , Jing Wen , Rongsheng Wang , Pengfei Wu

The advancement of Large Language Models (LLMs) for domain applications in fields such as materials science and engineering depends on the development of fine-tuning strategies that adapt models for specialized, technical capabilities. In…

Computation and Language · Computer Science 2024-09-06 Wei Lu , Rachel K. Luu , Markus J. Buehler

Large language models (LLMs) achieve remarkable advancements by leveraging tools to interact with environments, a critical step toward generalized AI. However, the standard supervised fine-tuning (SFT) approach, which relies on large-scale…

Computation and Language · Computer Science 2025-08-27 Junjie Ye , Yilong Wu , Sixian Li , Yuming Yang , Zhiheng Xi , Tao Gui , Qi Zhang , Xuanjing Huang , Peng Wang , Zhongchao Shi , Jianping Fan , Zhengyin Du

Prompt tuning, which involves training a small set of parameters, effectively enhances the pre-trained Vision-Language Models (VLMs) to downstream tasks. However, they often come at the cost of flexibility and adaptability when the tuned…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Mushui Liu , Bozheng Li , Yunlong Yu

In-Context Learning (ICL) allows Large Language Models (LLMs) to adapt to new tasks with just a few examples, but their predictions often suffer from systematic biases, leading to unstable performance in classification. While calibration…

Machine Learning · Statistics 2026-03-05 Korel Gundem , Juncheng Dong , Dennis Zhang , Vahid Tarokh , Zhengling Qi

Multi-modal Large Language Models (MLLMs) are increasingly prominent in the field of artificial intelligence. Visual instruction fine-tuning (IFT) is a vital process for aligning MLLMs' output with user's intentions. High-quality and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-18 Xiaotian Han , Yiqi Wang , Bohan Zhai , Quanzeng You , Hongxia Yang