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Structure-based virtual screening (SBVS) is a key computational strategy for identifying potential drug candidates by estimating the binding free energies (delta G_bind) of protein-ligand complexes. The immense size of chemical libraries,…

Quantum Physics · Physics 2025-07-15 Pei-Kun Yang

As the rapidly evolving field of machine learning continues to produce incredibly useful tools and models, the potential for quantum computing to provide speed up for machine learning algorithms is becoming increasingly desirable. In…

Quantum Physics · Physics 2024-04-02 Anthony M. Smaldone , Gregory W. Kyro , Victor S. Batista

Quantum convolutional neural networks (QCNNs) have been introduced as classifiers for gapped quantum phases of matter. Here, we propose a model-independent protocol for training QCNNs to discover order parameters that are unchanged under…

Quantum Physics · Physics 2023-06-05 Yu-Jie Liu , Adam Smith , Michael Knap , Frank Pollmann

Pneumonia poses a significant global health challenge, demanding accurate and timely diagnosis. While deep learning, particularly Convolutional Neural Networks (CNNs), has shown promise in medical image analysis for pneumonia detection,…

Machine Learning · Computer Science 2025-10-29 Gazi Tanbhir , Md. Farhan Shahriyar , Abdullah Md Raihan Chy

The proposed system consists of a two-stage cascade. The first stage performs a rough heartbeat detection while the second stage refines the previous one, improving the temporal localization and also classifying the heartbeats into types S1…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-06 J. Torre-Cruz , D. Martinez-Munoz , N. Ruiz-Reyes , A. J. Munoz-Montoro , M. Puentes-Chiachio , F. J. Canadas-Quesada

This paper proposes a new Quantum Spatial Graph Convolutional Neural Network (QSGCNN) model that can directly learn a classification function for graphs of arbitrary sizes. Unlike state-of-the-art Graph Convolutional Neural Network (GCNN)…

Machine Learning · Computer Science 2023-04-04 Lu Bai , Yuhang Jiao , Luca Rossi , Lixin Cui , Jian Cheng , Edwin R. Hancock

Quantum Machine Learning (QML) has seen significant advancements, driven by recent improvements in Noisy Intermediate-Scale Quantum (NISQ) devices. Leveraging quantum principles such as entanglement and superposition, quantum convolutional…

In this work, we are introducing a Quantum-Classical Bayesian Neural Network (QCBNN) that is capable to perform uncertainty-aware classification of classical medical dataset. This model is a symbiosis of a classical Convolutional NN that…

Quantum Physics · Physics 2024-06-11 Alona Sakhnenko , Julian Sikora , Jeanette Miriam Lorenz

Quantum convolutional neural networks (QCNNs) offer a promising architecture for near-term quantum machine learning by combining hierarchical feature extraction with modest parameter growth. However, any QCNN operating on classical data…

Quantum Physics · Physics 2025-12-16 Xingyun Feng

This paper presents a comprehensive evaluation of the potential of Quantum Convolutional Neural Networks (QCNNs) in comparison to classical Convolutional Neural Networks (CNNs) and Artificial / Classical Neural Network (ANN) models. With…

Quantum Physics · Physics 2023-07-25 Gowri Namratha Meedinti , Kandukuri Sai Srirekha , Radhakrishnan Delhibabu

This paper presents a hybrid quantum-classical machine learning model for classification tasks, integrating a 4-qubit quantum circuit with a classical neural network. The quantum circuit is designed to encode the features of the Iris…

Interpretation of electrocardiography (ECG) signals is required for diagnosing cardiac arrhythmia. Recently, machine learning techniques have been applied for automated computer-aided diagnosis. Machine learning tasks can be divided into…

Except for a few specific types, cardiac arrhythmias are not immediately life-threatening. However, if not treated appropriately, they can cause serious complications. In particular, atrial fibrillation, which is characterized by fast and…

Machine Learning · Computer Science 2020-10-08 Jérôme Van Zaen , Ricard Delgado-Gonzalo , Damien Ferrario Mathieu Lemay

This paper presents a novel quantum K-nearest neighbors (QKNN) algorithm, which offers improved performance over the classical k-NN technique by incorporating quantum computing (QC) techniques to enhance classification accuracy,…

Quantum Physics · Physics 2025-08-05 Asif Akhtab Ronggon , Md. Saifur Rahman

In recent years, with rapid progress in the development of quantum technologies, quantum machine learning has attracted a lot of interest. In particular, a family of hybrid quantum-classical neural networks, consisting of classical and…

Quantum Physics · Physics 2021-11-01 Yixiong Chen

Electrocardiogram (ECG) is the most frequent and routine diagnostic tool used for monitoring heart electrical signals and evaluating its functionality. The human heart can suffer from a variety of diseases, including cardiac arrhythmias.…

Signal Processing · Electrical Eng. & Systems 2022-09-05 Negin Alamatsaz , Leyla s Tabatabaei , Mohammadreza Yazdchi , Hamidreza Payan , Nima Alamatsaz , Fahimeh Nasimi

We explore the efficacy of the novel use of parametrised quantum circuits (PQCs) as quantum neural networks (QNNs) for forecasting time series signals with simulated quantum forward propagation. The temporal signals consist of several…

Quantum Physics · Physics 2022-02-02 Dimitrios Emmanoulopoulos , Sofija Dimoska

Congenital heart disease (CHD) is a critical condition that demands early detection, particularly in infancy and childhood. This study presents a deep learning model designed to detect CHD using phonocardiogram (PCG) signals, with a focus…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-01 Abdul Jabbar , Ethan Grooby , Jack Crozier , Alexander Gallon , Vivian Pham , Khawza I Ahmad , Md Hassanuzzaman , Raqibul Mostafa , Ahsan H. Khandoker , Faezeh Marzbanrad

Advances in classical machine learning and single-cell technologies have paved the way to understand interactions between disease cells and tumor microenvironments to accelerate therapeutic discovery. However, challenges in these machine…

Quantum Physics · Physics 2023-10-18 Anupama Ray , Dhiraj Madan , Srushti Patil , Maria Anna Rapsomaniki , Pushpak Pati

Congenital anomalies arising as a result of a defect in the structure of the heart and great vessels are known as congenital heart diseases or CHDs. A PCG can provide essential details about the mechanical conduction system of the heart and…