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A causal query will commonly not be identifiable from observed data, in which case no estimator of the query can be contrived without further assumptions or measured variables, regardless of the amount or precision of the measurements of…

Methodology · Statistics 2021-12-09 Michael C Sachs , Gustav Jonzon , Arvid Sjölander , Erin E Gabriel

Mathematical models of measuring systems and processes play an essential role in metrology and practical measurements. They form the basis for understanding and evaluating measurements, their results and their trustworthiness. Classic…

Systems and Control · Electrical Eng. & Systems 2024-08-13 Nadine Schiering , Sascha Eichstaedt , Michael Heizmann , Wolfgang Koch , Linda-Sophie Schneider , Stephan Scheele , Klaus-Dieter Sommer

The features of a logically sound approach to a theory of statistical reasoning are discussed. A particular approach that satisfies these criteria is reviewed. This is seen to involve selection of a model, model checking, elicitation of a…

Statistics Theory · Mathematics 2018-05-09 Luai Al-Labadi , Zeynep Baskurt , Michael Evans

Mathematical models and algorithms are an essential part of mathematical research data, as they are epistemically grounding numerical data. In order to represent models and algorithms as well as their relationship semantically to make this…

In social science, formal and quantitative models, such as ones describing economic growth and collective action, are used to formulate mechanistic explanations, provide predictions, and uncover questions about observed phenomena. Here, we…

Symbolic Computation · Computer Science 2023-08-17 Julia Balla , Sihao Huang , Owen Dugan , Rumen Dangovski , Marin Soljacic

Inferring from inconsistency and making decisions are two problems which have always been treated separately by researchers in Artificial Intelligence. Consequently, different models have been proposed for each category. Different…

Artificial Intelligence · Computer Science 2012-07-09 Leila Amgoud

Large-scale datasets are increasingly being used to inform decision making. While this effort aims to ground policy in real-world evidence, challenges have arisen as selection bias and other forms of distribution shifts often plague…

Methodology · Statistics 2023-11-07 Santiago Cortes-Gomez , Mateo Dulce , Carlos Patino , Bryan Wilder

Standard statistical theory has arguably proved to be unsuitable as a basis for constructing a satisfactory completely general framework for performing statistical inference. For example, frequentist theory has never come close to providing…

Other Statistics · Statistics 2025-04-24 Russell J. Bowater

Understanding the mechanisms of interactions within cells, tissues, and organisms is crucial to driving developments across biology and medicine. Mathematical modeling is an essential tool for simulating biological systems and revealing…

Molecular Networks · Quantitative Biology 2024-08-13 Lingxia Qiao , Ali Khalilimeybodi , Nathaniel J Linden-Santangeli , Padmini Rangamani

When teaching and discussing statistical assumptions, our focus is oftentimes placed on how to test and address potential violations rather than the effects of violating assumptions on the estimates produced by our statistical models. The…

Methodology · Statistics 2022-06-14 Ian A Silver

We introduce methodology to bridge scenario analysis and model-based risk forecasting, leveraging their respective strengths in policy settings. Our Bayesian framework addresses the fundamental challenge of reconciling judgmental narrative…

Econometrics · Economics 2025-05-09 Tobias Adrian , Domenico Giannone , Matteo Luciani , Mike West

Formalisms for specifying statistical models, such as probabilistic-programming languages, typically consist of two components: a specification of a stochastic process (the prior), and a specification of observations that restrict the…

Databases · Computer Science 2015-01-06 Vince Barany , Balder ten Cate , Benny Kimelfeld , Dan Olteanu , Zografoula Vagena

Inference is the process of using facts we know to learn about facts we do not know. A theory of inference gives assumptions necessary to get from the former to the latter, along with a definition for and summary of the resulting…

Machine Learning · Statistics 2021-09-27 Beau Coker , Cynthia Rudin , Gary King

We propose an interdisciplinary framework that combines Bayesian predictive inference, a well-established tool in Machine Learning, with Formal Methods rooted in the computer science community. Bayesian predictive inference allows for…

Computation · Statistics 2025-08-21 Laura Vana , Ennio Visconti , Laura Nenzi , Annalisa Cadonna , Gregor Kastner

Causal discovery, the task of inferring causal structure from data, has the potential to uncover mechanistic insights from biological experiments, especially those involving perturbations. However, causal discovery algorithms over larger…

Machine Learning · Computer Science 2025-04-01 Menghua Wu , Yujia Bao , Regina Barzilay , Tommi Jaakkola

Comparisons of different treatments or production processes are the goals of a significant fraction of applied research. Unsurprisingly, two-sample problems play a main role in Statistics through natural questions such as `Is the the new…

Methodology · Statistics 2017-09-05 P. C. Álvarez-Esteban , E. del Barrio , J. A. Cuesta-Albertos , C. Matrán

Turning rich neuroimaging data into mechanistic insight remains challenging. Statistical models capture associations but remain largely agnostic to underlying mechanisms. Biophysical models embody candidate mechanisms but remain difficult…

Neurons and Cognition · Quantitative Biology 2026-01-15 Dominic Boutet , Sylvain Baillet

We examine the role of textual data as study units when conducting causal inference by drawing parallels between human subjects and organized texts. %in human population research. We elaborate on key causal concepts and principles, and…

Computation and Language · Computer Science 2022-02-03 Bo Zhang , Jiayao Zhang

Statistical modeling plays a fundamental role in understanding the underlying mechanism of massive data (statistical inference) and predicting the future (statistical prediction). Although all models are wrong, researchers try their best to…

Methodology · Statistics 2020-06-17 Hangjin Jiang

Nowadays, the interpretability of machine learning models is becoming increasingly important, especially in the medical domain. Aiming to shed some light on how to rationalize medical relation prediction, we present a new interpretable…

Computation and Language · Computer Science 2020-05-05 Zhen Wang , Jennifer Lee , Simon Lin , Huan Sun