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This paper analyzes the working or default assumptions researchers in the formal, statistical, and case study traditions typically hold regarding the sources of unexplained variance, the meaning of outliers, parameter values, human…

Methodology · Statistics 2022-02-17 Andrew Bennett , Bear F. Braumoeller

Basic principles of mathematical modeling are reviewed in this book, with the focus on physics and its practical applications, and examples of selected mathematical methods are presented. Most of the models have been imported from physics…

Classical Physics · Physics 2025-07-14 Sergej Pankratow

A unified mathematical language for medicine and science will be presented. Using this language, models for DNA replication, protein synthesis, chemical reactions, neurons and a cardiac cycle of a heart have been built. Models for Turing…

Quantitative Methods · Quantitative Biology 2014-09-18 Patrick St-Amant

Latent space models have been widely adopted in modeling network data. Developing statistical inference for estimated model parameters enables quantifying associated uncertainty and is pivotal for downstream tasks. Despite recent progress…

Statistics Theory · Mathematics 2026-05-12 Yuang Tian , Jiajin Sun , Yinqiu He

This article provides an overview on the statistical modeling of complex data as increasingly encountered in modern data analysis. It is argued that such data can often be described as elements of a metric space that satisfies certain…

Methodology · Statistics 2024-02-28 Paromita Dubey , Yaqing Chen , Hans-Georg Müller

As predictive algorithms grow in popularity, using the same dataset to both train and test a new model has become routine across research, policy, and industry. Sample-splitting attains valid inference on model properties by using separate…

Econometrics · Economics 2025-11-27 Bruno Fava

We present and discuss a curated selection of recent literature related to the application of quantitative techniques, tools, and topics from mathematics and data science that have been used to analyze the mathematical sciences community.…

In scientific inference problems, the underlying statistical modeling assumptions have a crucial impact on the end results. There exist, however, only a few automatic means for validating these fundamental modelling assumptions. The…

Methodology · Statistics 2019-05-21 Andreas Svensson , Dave Zachariah , Petre Stoica , Thomas B. Schön

In the Humanities and Social Sciences, there is increasing interest in approaches to information extraction, prediction, intelligent linkage, and dimension reduction applicable to large text corpora. With approaches in these fields being…

Applications · Statistics 2019-04-16 Vanessa Glenny , Jonathan Tuke , Nigel Bean , Lewis Mitchell

We consider basic conceptual questions concerning the relationship between statistical estimation and causal inference. Firstly, we show how to translate causal inference problems into an abstract statistical formalism without requiring any…

Statistics Theory · Mathematics 2020-07-22 Oliver J. Maclaren , Ruanui Nicholson

Although language models demonstrate remarkable proficiency on mathematical benchmarks, it remains unclear whether this reflects true mathematical reasoning or statistical pattern matching over learning formal syntax. Most existing…

Artificial Intelligence · Computer Science 2026-04-27 Michael Cooper , Samuel Cooper

The fundamental challenge of drawing causal inference is that counterfactual outcomes are not fully observed for any unit. Furthermore, in observational studies, treatment assignment is likely to be confounded. Many statistical methods have…

Methodology · Statistics 2022-08-01 Harsh Parikh , Carlos Varjao , Louise Xu , Eric Tchetgen Tchetgen

Causal inference, estimating causal effects from observational data, is a fundamental tool in many disciplines. Of particular importance across a variety of domains is the continuous treatment setting, where the variable of intervention has…

Machine Learning · Computer Science 2026-05-15 Christopher Stith , Medha Barath , Vahid Balazadeh , Jesse C. Cresswell , Rahul G. Krishnan

This paper discusses the fundamental principles of causal inference - the area of statistics that estimates the effect of specific occurrences, treatments, interventions, and exposures on a given outcome from experimental and observational…

Methodology · Statistics 2021-12-03 Francesca Dominici , Falco J. Bargagli-Stoffi , Fabrizia Mealli

Statistical and structural modeling represent two distinct approaches to data analysis. In this paper, we propose a set of novel methods for combining statistical and structural models for improved prediction and causal inference. Our first…

Econometrics · Economics 2020-06-11 Jiaming Mao , Jingzhi Xu

This paper compares a qualitative reasoning model of translation with a quantitative statistical model. We consider these models within the context of two hypothetical speech translation systems, starting with a logic-based design and…

cmp-lg · Computer Science 2008-02-03 Hiyan Alshawi

In biomedical research, repeated measurements within each subject are often processed to remove artifacts and unwanted sources of variation. The resulting data are used to construct derived outcomes that act as proxies for scientific…

Methodology · Statistics 2026-02-03 Zihang Wang , Razieh Nabi , Benjamin B. Risk

Qualitative research is an approach to understanding social phenomenon based around human interpretation of data, particularly text. Probabilistic topic modelling is a machine learning approach that is also based around the analysis of text…

Human-Computer Interaction · Computer Science 2022-10-04 Marco Gillies , Dhiraj Murthy , Harry Brenton , Rapheal Olaniyan

Statistical inference as a formal scientific method to covert experience to knowledge has proven to be elusively difficult. While frequentist and Bayesian methodologies have been accepted in the contemporary era as two dominant schools of…

Statistics Theory · Mathematics 2023-01-16 Chuanhai Liu , Ryan Martin

Mathematical modelling allows us to concisely describe fundamental principles in biology. Analysis of models can help to both explain known phenomena, and predict the existence of new, unseen behaviours. Model analysis is often a complex…

Quantitative Methods · Quantitative Biology 2020-08-13 Mark Blyth , Ludovic Renson , Lucia Marucci