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Pathology Foundation Models (FMs) hold great promise for healthcare. Before they can be used in clinical practice, it is essential to ensure they are robust to variations between medical centers. We measure whether pathology FMs focus on…

Machine Learning · Computer Science 2025-02-04 Edwin D. de Jong , Eric Marcus , Jonas Teuwen

Due to lack of annotated pathological images, transfer learning has been the predominant approach in the field of digital pathology.Pre-trained neural networks based on ImageNet database are often used to extract "off the shelf" features,…

Image and Video Processing · Electrical Eng. & Systems 2022-01-04 Xingyu Li , Min Cen , Jinfeng Xu , Hong Zhang , Xu Steven Xu

Content-based mammographic image retrieval systems require exact BIRADS categorical matching across five distinct classes, presenting significantly greater complexity than binary classification tasks commonly addressed in literature.…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 MD Shaikh Rahman , Feiroz Humayara , Syed Maudud E Rabbi , Muhammad Mahbubur Rashid

Confounding pathology with normal anatomical variation remains a significant challenge in unsupervised medical-image anomaly detection, resulting in numerous false positives. To enhance integration of healthy variation, we augment the…

Quantitative Methods · Quantitative Biology 2026-03-09 P. Bilha Githinji , Xi Yuan , Ijaz Gul , Lian Zhang , Jinhao Xu , Zhenglin Chen , Peiwu Qin , Dongmei Yu

The deployment of Machine Learning models intraoperatively for tissue characterisation can assist decision making and guide safe tumour resections. For image classification models, pixel attribution methods are popular to infer…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Alfie Roddan , Chi Xu , Serine Ajlouni , Irini Kakaletri , Patra Charalampaki , Stamatia Giannarou

Parallel imaging techniques reduce magnetic resonance imaging (MRI) scan time but image quality degrades as the acceleration factor increases. In clinical practice, conservative acceleration factors are chosen because no mechanism exists to…

Image and Video Processing · Electrical Eng. & Systems 2026-05-26 Ilias I. Giannakopoulos , Lokesh B Gautham Muthukumar , Yvonne W. Lui , Riccardo Lattanzi

Large Language Models (LLMs) are increasingly used for medical entity extraction, yet their confidence scores are often miscalibrated, limiting safe deployment in clinical settings. We present a conformal prediction framework that provides…

Computation and Language · Computer Science 2026-03-10 Manil Shrestha , Edward Kim

Foundation models for computational pathology are expected to facilitate the development of high-performing, generalisable deep learning systems. However, in addition to biologically relevant features, current foundation models also capture…

Background and objective Risk prediction models aim at identifying people at higher risk of developing a target disease. Feature selection is particularly important to improve the prediction model performance avoiding overfitting and to…

Machine Learning · Computer Science 2024-02-09 N. Cueto-López , M. T. García-Ordás , V. Dávila-Batista , V. Moreno , N. Aragonés , R. Alaiz-Rodríguez

The adoption of neural network models in medical imaging has been constrained by strict privacy regulations, limited data availability, high acquisition costs, and demographic biases. Deep generative models offer a promising solution by…

Image and Video Processing · Electrical Eng. & Systems 2025-06-16 Zuzanna Skorniewska , Bartlomiej W. Papiez

Trained using only image class label, deep weakly supervised methods allow image classification and ROI segmentation for interpretability. Despite their success on natural images, they face several challenges over histology data where ROI…

Image and Video Processing · Electrical Eng. & Systems 2022-05-13 Soufiane Belharbi , Jérôme Rony , Jose Dolz , Ismail Ben Ayed , Luke McCaffrey , Eric Granger

While datasets with single-label supervision have propelled rapid advances in image classification, additional annotations are necessary in order to quantitatively assess how models make predictions. To this end, for a subset of ImageNet…

Computer Vision and Pattern Recognition · Computer Science 2022-01-27 Mazda Moayeri , Phillip Pope , Yogesh Balaji , Soheil Feizi

Visual attribute imbalance is a common yet underexplored issue in image classification, significantly impacting model performance and generalization. In this work, we first define the first-level and second-level attributes of images and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Jiayi Chen , Yanbiao Ma , Andi Zhang , Weidong Tang , Wei Dai , Bowei Liu

Identification of plant disease is usually done through visual inspection or during laboratory examination which causes delays resulting in yield loss by the time identification is complete. On the other hand, complex deep learning models…

Computer Vision and Pattern Recognition · Computer Science 2021-02-10 Nisar Ahmed , Hafiz Muhammad Shahzad Asif , Gulshan Saleem

Deep neural networks for medical image segmentation often produce overconfident results misaligned with empirical observations. Such miscalibration, challenges their clinical translation. We propose to use marginal L1 average calibration…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Theodore Barfoot , Luis Garcia-Peraza-Herrera , Ben Glocker , Tom Vercauteren

Current methods for developing foundation models in medical image segmentation rely on two primary assumptions: a fixed set of classes and the immediate availability of a substantial and diverse training dataset. However, this can be…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Xiaoyang Chen , Hao Zheng , Yifang Xie , Yuncong Ma , Tengfei Li

Deep learning techniques show success in detecting objects in medical images, but still suffer from false-positive predictions that may hinder accurate diagnosis. The estimated uncertainty of the neural network output has been used to flag…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Ishaan Bhat , Josien P. W. Pluim , Max A. Viergever , Hugo J. Kuijf

A large number of papers have introduced novel machine learning and feature extraction methods for automatic classification of AD. However, they are difficult to reproduce because key components of the validation are often not readily…

Although deep learning models for abnormality classification can perform well in screening mammography, the demographic, imaging, and clinical characteristics associated with increased risk of model failure remain unclear. This…

This study evaluates the reliability of two deep learning models for skin cancer detection, focusing on their explainability and fairness. Using the HAM10000 dataset of dermatoscopic images, the research assesses two convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2024-09-09 Tanish Jain