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Structure-based drug design aims at generating high affinity ligands with prior knowledge of 3D target structures. Existing methods either use conditional generative model to learn the distribution of 3D ligands given target binding sites,…

Biomolecules · Quantitative Biology 2024-03-18 Yuwei Yang , Siqi Ouyang , Xueyu Hu , Mingyue Zheng , Hao Zhou , Lei Li

3D shapes captured by scanning devices are often incomplete due to occlusion. 3D shape completion methods have been explored to tackle this limitation. However, most of these methods are only trained and tested on a subset of categories,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Lintai Wu , Junhui Hou , Linqi Song , Yong Xu

Self-supervised learning has recently gained growing interest in molecular modeling for scientific tasks such as AI-assisted drug discovery. Current studies consider leveraging both 2D and 3D molecular structures for representation…

Machine Learning · Computer Science 2023-10-10 Qiying Yu , Yudi Zhang , Yuyan Ni , Shikun Feng , Yanyan Lan , Hao Zhou , Jingjing Liu

The difficulties in both data acquisition and annotation substantially restrict the sample sizes of training datasets for 3D medical imaging applications. As a result, constructing high-performance 3D convolutional neural networks from…

Image and Video Processing · Electrical Eng. & Systems 2022-01-06 Shu Zhang , Zihao Li , Hong-Yu Zhou , Jiechao Ma , Yizhou Yu

Reconstructing 3D human shapes from 2D images has received increasing attention recently due to its fundamental support for many high-level 3D applications. Compared with natural images, freehand sketches are much more flexible to depict…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Fei Wang , Kongzhang Tang , Hefeng Wu , Baoquan Zhao , Hao Cai , Teng Zhou

Recently, 3D anomaly detection, a crucial problem involving fine-grained geometry discrimination, is getting more attention. However, the lack of abundant real 3D anomaly data limits the scalability of current models. To enable scalable…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Wenqiao Li , Xiaohao Xu , Yao Gu , Bozhong Zheng , Shenghua Gao , Yingna Wu

Graph Neural Networks (GNN) have been shown to work effectively for modeling graph structured data to solve tasks such as node classification, link prediction and graph classification. There has been some recent progress in defining the…

Machine Learning · Computer Science 2020-02-04 Ekagra Ranjan , Soumya Sanyal , Partha Pratim Talukdar

Statistical shape modeling (SSM) is widely used in biology and medicine as a new generation of morphometric approaches for the quantitative analysis of anatomical shapes. Technological advancements of in vivo imaging have led to the…

Purpose: Semantic segmentation and landmark detection are fundamental tasks of medical image processing, facilitating further analysis of anatomical objects. Although deep learning-based pixel-wise classification has set a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Ron Keuth , Lasse Hansen , Maren Balks , Ronja Jäger , Anne-Nele Schröder , Ludger Tüshaus , Mattias Heinrich

Accurate classification and anatomical localization are essential for effective medical diagnostics and research, which may be efficiently performed using deep learning techniques. However, availability of limited labeled data poses a…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Mohammed Abdul Hafeez Khan , Samuel Morries Boddepalli , Siddhartha Bhattacharyya , Debasis Mitra

We propose a scalable neural network framework to reconstruct the 3D mesh of a human body from multi-view images, in the subspace of the SMPL model. Use of multi-view images can significantly reduce the projection ambiguity of the problem,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-27 Junbang Liang , Ming C. Lin

One of the essential tasks in connectomics is the morphology analysis of neurons and organelles like mitochondria to shed light on their biological properties. However, these biological objects often have tangled parts or complex branching…

Computer Vision and Pattern Recognition · Computer Science 2020-04-22 Abhimanyu Talwar , Zudi Lin , Donglai Wei , Yuesong Wu , Bowen Zheng , Jinglin Zhao , Won-Dong Jang , Xueying Wang , Jeff W. Lichtman , Hanspeter Pfister

Inpainting has recently been proposed as a successful deep learning technique for unsupervised medical image model discovery. The masks used for inpainting are generally independent of the dataset and are not tailored to perform on…

Image and Video Processing · Electrical Eng. & Systems 2022-07-14 Yousef Yeganeh , Azade Farshad , Nassir Navab

Polygonal modeling is a core task of content creation in Computer Graphics. The complexity of modeling, in terms of the number and the order of operations and time required to execute them makes it challenging to learn and execute. Our goal…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 I-Chao Shen , Yu Ju Chen , Oliver van Kaick , Takeo Igarashi

Radiological images such as computed tomography (CT) and X-rays render anatomy with intrinsic structures. Being able to reliably locate the same anatomical structure across varying images is a fundamental task in medical image analysis. In…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Ke Yan , Jinzheng Cai , Dakai Jin , Shun Miao , Dazhou Guo , Adam P. Harrison , Youbao Tang , Jing Xiao , Jingjing Lu , Le Lu

Radiologists rely on anatomical understanding to accurately delineate pathologies, yet most current deep learning approaches use pure pattern recognition and ignore the anatomical context in which pathologies develop. To narrow this gap, we…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Keyi Li , Alexander Jaus , Jens Kleesiek , Rainer Stiefelhagen

We introduce a data-driven approach to complete partial 3D shapes through a combination of volumetric deep neural networks and 3D shape synthesis. From a partially-scanned input shape, our method first infers a low-resolution -- but…

Computer Vision and Pattern Recognition · Computer Science 2017-04-13 Angela Dai , Charles Ruizhongtai Qi , Matthias Nießner

Fueled by recent advances in machine learning, there has been tremendous progress in the field of semantic segmentation for the medical image computing community. However, developed algorithms are often optimized and validated by hand based…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Oliver Rippel , Leon Weninger , Dorit Merhof

3D modeling is becoming a well-developed field of medicine, but its applicability can be limited due to the lack of software allowing for easy utilizations of generated 3D visualizations. By leveraging recent advances in virtual reality, we…

Human-Computer Interaction · Computer Science 2020-12-07 Alex J. Deakyne , Erik N. Gaasedelen , Tinen L. Iles , Paul A. Iaizzo

Multimodal learning leverages complementary information derived from different modalities, thereby enhancing performance in medical image segmentation. However, prevailing multimodal learning methods heavily rely on extensive well-annotated…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Xiaogen Zhou , Yiyou Sun , Min Deng , Winnie Chiu Wing Chu , Qi Dou