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Electrocardiogram (ECG) analysis is crucial for diagnosing heart disease, but most self-supervised learning methods treat ECG as a generic time series, overlooking physiologic semantics and rhythm-level structure. Existing contrastive…

Machine Learning · Computer Science 2026-02-27 Xin Wang , Burcu Ozek , Aruna Mohan , Amirhossein Ravari , Or Zilbershot , Fatemeh Afghah

Genomic regions represent features such as gene annotations, transcription factor binding sites and epigenetic modifications. Performing various genomic operations such as identifying overlapping/non-overlapping regions or nearest gene…

Databases · Computer Science 2020-08-18 Matloob Khushi

The multimodal datasets can be leveraged to pre-train large-scale vision-language models by providing cross-modal semantics. Current endeavors for determining the usage of datasets mainly focus on single-modal dataset ownership verification…

Information Retrieval · Computer Science 2025-04-18 Wenyi Zhang , Ju Jia , Xiaojun Jia , Yihao Huang , Xinfeng Li , Cong Wu , Lina Wang

Recent work on tokenizer-free multilingual pretrained models show promising results in improving cross-lingual transfer and reducing engineering overhead (Clark et al., 2022; Xue et al., 2022). However, these works mainly focus on reporting…

Computation and Language · Computer Science 2022-10-14 Jimin Sun , Patrick Fernandes , Xinyi Wang , Graham Neubig

Epigenetics encompasses mechanisms that can alter the expression of genes without changing the underlying genetic sequence. The epigenetic regulation of gene expression is initiated and sustained by several mechanisms such as DNA…

Genomics · Quantitative Biology 2025-04-08 Muhammad Tahir , Mahboobeh Norouzi , Shehroz S. Khan , James R. Davie , Soichiro Yamanaka , Ahmed Ashraf

Pretrained using large amount of data, autoregressive language models are able to generate high quality sequences. However, these models do not perform well under hard lexical constraints as they lack fine control of content generation…

Computation and Language · Computer Science 2021-03-18 Lee-Hsun Hsieh , Yang-Yin Lee , Ee-Peng Lim

Tokenizer adaptation plays an important role in adapting pre-trained language models to new domains or languages. In this work, we address two complementary aspects of this process: vocabulary extension and pruning. The common approach to…

Computation and Language · Computer Science 2026-03-24 Taido Purason , Pavel Chizhov , Ivan P. Yamshchikov , Mark Fishel

Subgraph GNNs enhance message-passing GNNs expressivity by representing graphs as sets of subgraphs, demonstrating impressive performance across various tasks. However, their scalability is hindered by the need to process large numbers of…

Machine Learning · Computer Science 2025-06-02 Guy Bar-Shalom , Yam Eitan , Fabrizio Frasca , Haggai Maron

Tokenization is used almost universally by modern language models, enabling efficient text representation using multi-byte or multi-character tokens. However, prior work has shown that tokenization can introduce distortion into the model's…

Computation and Language · Computer Science 2026-05-08 Jonathan Hayase , Alisa Liu , Noah A. Smith , Sewoong Oh

Accurate automatic segmentation of brain anatomy from $T_1$-weighted~($T_1$-w) magnetic resonance images~(MRI) has been a computationally intensive bottleneck in neuroimaging pipelines, with state-of-the-art results obtained by unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Amod Jog , Bruce Fischl

Deep learning has achieved remarkable success in modeling sequential data, including event sequences, temporal point processes, and irregular time series. Recently, transformers have largely replaced recurrent networks in these tasks.…

Machine Learning · Computer Science 2025-08-05 Ivan Karpukhin , Andrey Savchenko

Symbolic regression is an important but challenging research topic in data mining. It can detect the underlying mathematical models. Genetic programming (GP) is one of the most popular methods for symbolic regression. However, its…

Data Structures and Algorithms · Computer Science 2017-05-16 Chen Chen , Changtong Luo , Zonglin Jiang

The rapid advancements in large language models (LLMs) have ignited interest in the temporal knowledge graph (tKG) domain, where conventional embedding-based and rule-based methods dominate. The question remains open of whether pre-trained…

Computation and Language · Computer Science 2024-04-18 Ruotong Liao , Xu Jia , Yangzhe Li , Yunpu Ma , Volker Tresp

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

This work studies ensemble learning for graph neural networks (GNNs) under the popular semi-supervised setting. Ensemble learning has shown superiority in improving the accuracy and robustness of traditional machine learning by combining…

Machine Learning · Computer Science 2024-05-07 Xin Zhang , Daochen Zha , Qiaoyu Tan

Recently, Temporal Graph Neural Networks (TGNNs) have demonstrated state-of-the-art performance in various high-impact applications, including fraud detection and content recommendation. Despite the success of TGNNs, they are prone to the…

Machine Learning · Computer Science 2024-11-26 Gangda Deng , Hongkuan Zhou , Hanqing Zeng , Yinglong Xia , Christopher Leung , Jianbo Li , Rajgopal Kannan , Viktor Prasanna

Three-dimensional medical image segmentation is a fundamental yet computationally demanding task due to the cubic growth of voxel processing and the redundant computation on homogeneous regions. To address these limitations, we propose…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Sen Zeng , Hong Zhou , Zheng Zhu , Yang Liu

How to best develop foundational models for time series forecasting remains an important open question. Tokenization is a crucial consideration in this effort: what is an effective discrete vocabulary for a real-valued sequential input? To…

Medical Referring Image Segmentation (MRIS) involves segmenting target regions in medical images based on natural language descriptions. While achieving promising results, recent approaches usually involve complex design of multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Xinyu Chen , Yiran Wang , Gaoyang Pang , Jiafu Hao , Chentao Yue , Luping Zhou , Yonghui Li

The two most common data-structures for genome indexing, FM-indices and hash-tables, exhibit a fundamental trade-off between memory footprint and performance. We present Ranger, a new indexing technique for nucleotide sequences that is both…

Data Structures and Algorithms · Computer Science 2023-08-09 Alon Rashelbach , Ori Rottensterich , Mark Silberstien