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Summary: With the rapid development of long-read sequencing technologies, the era of individual complete genomes is approaching. We have developed wgatools, a cross-platform, ultrafast toolkit that supports a range of whole genome alignment…

Genomics · Quantitative Biology 2025-04-01 Wenjie Wei , Songtao Gui , Jian Yang , Erik Garrison , Jianbing Yan , Hai-Jun Liu

Python's dynamic typing system offers flexibility and expressiveness but can lead to type-related errors, prompting the need for automated type inference to enhance type hinting. While existing learning-based approaches show promising…

Software Engineering · Computer Science 2024-08-14 Chong Wang , Jian Zhang , Yiling Lou , Mingwei Liu , Weisong Sun , Yang Liu , Xin Peng

Visual autoregressive (AR) generation offers a promising path toward unifying vision and language models, yet its performance remains suboptimal against diffusion models. Prior work often attributes this gap to tokenizer limitations and…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Qiyuan He , Yicong Li , Haotian Ye , Jinghao Wang , Xinyao Liao , Pheng-Ann Heng , Stefano Ermon , James Zou , Angela Yao

The quality of the latent space in visual tokenizers (e.g., VAEs) is crucial for modern generative models. However, the standard reconstruction-based training paradigm produces a latent space that is biased towards low-level information,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Jingfeng Yao , Yuda Song , Yucong Zhou , Xinggang Wang

This study introduces a novel knowledge enhanced tokenisation mechanism, K-Tokeniser, for clinical text processing. Technically, at initialisation stage, K-Tokeniser populates global representations of tokens based on semantic types of…

Computation and Language · Computer Science 2024-06-21 Abul Hasan , Jinge Wu , Quang Ngoc Nguyen , Salomé Andres , Imane Guellil , Huayu Zhang , Arlene Casey , Beatrice Alex , Bruce Guthrie , Honghan Wu

While deep learning has made impressive progress in speech synthesis and voice conversion, the assessment of the synthesized speech is still carried out by human participants. Several recent papers have proposed deep-learning-based…

Audio and Speech Processing · Electrical Eng. & Systems 2020-11-10 Yeunju Choi , Youngmoon Jung , Hoirin Kim

Fine-tuning provides an effective means to specialize pre-trained models for various downstream tasks. However, fine-tuning often incurs high memory overhead, especially for large transformer-based models, such as LLMs. While existing…

Computation and Language · Computer Science 2025-02-03 Antoine Simoulin , Namyong Park , Xiaoyi Liu , Grey Yang

Similar to natural language models, pre-trained genome language models are proposed to capture the underlying intricacies within genomes with unsupervised sequence modeling. They have become essential tools for researchers and practitioners…

Genomics · Quantitative Biology 2024-06-04 Siyuan Li , Zedong Wang , Zicheng Liu , Di Wu , Cheng Tan , Jiangbin Zheng , Yufei Huang , Stan Z. Li

Relational graph neural networks (RGNNs) are graph neural networks with dedicated structures for modeling the different types of nodes and edges in heterogeneous graphs. While RGNNs have been increasingly adopted in many real-world…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-04-10 Kun Wu , Mert Hidayetoğlu , Xiang Song , Sitao Huang , Da Zheng , Israt Nisa , Wen-mei Hwu

We present SegINR, a novel approach to neural Text-to-Speech (TTS) that addresses sequence alignment without relying on an auxiliary duration predictor and complex autoregressive (AR) or non-autoregressive (NAR) frame-level sequence…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-22 Minchan Kim , Myeonghun Jeong , Joun Yeop Lee , Nam Soo Kim

Time series forecasting plays a vital role in supporting decision-making across a wide range of critical applications, including energy, healthcare, and finance. Despite recent advances, forecasting accuracy remains limited due to the…

Machine Learning · Computer Science 2025-08-14 Xiaoyu Tao , Shilong Zhang , Mingyue Cheng , Daoyu Wang , Tingyue Pan , Bokai Pan , Changqing Zhang , Shijin Wang

This study presents an integrated approach for advancing functional Near-Infrared Spectroscopy (fNIRS) neuroimaging through the synthesis of data and application of machine learning models. By addressing the scarcity of high-quality…

Signal Processing · Electrical Eng. & Systems 2024-05-21 Eitan Waks

Transformer-based entropy models have gained prominence in recent years due to their superior ability to capture long-range dependencies in probability distribution estimation compared to convolution-based methods. However, previous…

Computer Vision and Pattern Recognition · Computer Science 2024-05-03 Daxin Li , Yuanchao Bai , Kai Wang , Junjun Jiang , Xianming Liu , Wen Gao

Utilizing transformer architectures for semantic segmentation of high-resolution images is hindered by the attention's quadratic computational complexity in the number of tokens. A solution to this challenge involves decreasing the number…

Computer Vision and Pattern Recognition · Computer Science 2024-05-24 Daniel Kienzle , Marco Kantonis , Robin Schön , Rainer Lienhart

While model architecture and training objectives are well-studied, tokenization, particularly in multilingual contexts, remains a relatively neglected aspect of Large Language Model (LLM) development. Existing tokenizers often exhibit high…

Tokenization is an understudied and often neglected component of modern LLMs. Most published works use a single tokenizer for all experiments, often borrowed from another model, without performing ablations or analysis to optimize…

Computation and Language · Computer Science 2024-02-08 Gautier Dagan , Gabriel Synnaeve , Baptiste Rozière

Graph Neural Networks (GNNs) are emerging ML models to analyze graph-structure data. Graph Neural Network (GNN) execution involves both compute-intensive and memory-intensive kernels, the latter dominates the total time, being significantly…

As large language models move toward million-token context windows, CPU tokenizers become a major slowdown because they process text one step at a time while powerful GPUs sit unused. We built a GPU-based byte-level BPE tokenizer that…

Computation and Language · Computer Science 2026-03-04 Venu Gopal Kadamba , Kanishkha Jaisankar

Large Language Models (LLMs) have demonstrated remarkable generalization across diverse tasks, leading individuals to increasingly use them as personal assistants and universal computing engines. Nevertheless, a notable obstacle emerges…

Machine Learning · Computer Science 2023-09-13 Dimitris Spathis , Fahim Kawsar

Tokenisation - "the process of splitting text into atomic parts" (Brezina & Timperley, 2017: 1) - is a crucial step for corpus linguistics, as it provides the basis for any applicable quantitative method (e.g. collocations) while ensuring…

Computation and Language · Computer Science 2025-07-03 Matteo Di Cristofaro