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The detection of biomolecules at the single molecular level have important applications in the fields of biosensing and biomedical diagnosis. Solid state nanopore (SS-nanopore) is an effective tool to perform the single molecular detection,…

Biological Physics · Physics 2022-10-14 Jing Yang , Juan Wang , Ranfeng Wu , Yiming Chen , Cheng Zhang

Deep Convolutional Neural Network (CNN) is a special type of Neural Networks, which has shown exemplary performance on several competitions related to Computer Vision and Image Processing. Some of the exciting application areas of CNN…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Asifullah Khan , Anabia Sohail , Umme Zahoora , Aqsa Saeed Qureshi

Phase retrieval, the problem of recovering lost phase information from measured intensity alone, is an inverse problem that is widely faced in various imaging modalities ranging from astronomy to nanoscale imaging. The current process of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-12 Henry Chan , Youssef S. G. Nashed , Saugat Kandel , Stephan Hruszkewycz , Subramanian Sankaranarayanan , Ross J. Harder , Mathew J. Cherukara

A solid-state nanopore can electrophoretically capture a DNA molecule and pull it through in a folded configuration. The resulting ionic current signal indicates where along its length the DNA was captured. A statistical study using an 8 nm…

Biological Physics · Physics 2015-06-11 Mirna Mihovilovic , Nick Hagerty , Derek Stein

In the present paper, we propose a source camera identification method for mobile devices based on deep learning. Recently, convolutional neural networks (CNNs) have shown a remarkable performance on several tasks such as image recognition,…

Computer Vision and Pattern Recognition · Computer Science 2018-01-25 David Freire-Obregón , Fabio Narducci , Silvio Barra , Modesto Castrillón-Santana

Solid-state nanopore and nanopipette sensors are powerful devices for the detection, quantification and structural analysis of biopolymers such as DNA and proteins, especially in carrier-enhanced resistive-pulse sensing. However, hundreds…

Mesoscale and Nanoscale Physics · Physics 2025-10-14 Cengiz J. Khan , Oliver J. Irving , Rand A. Al-Waqfi , Giorgio Ferrari , Tim Albrecht

Deep Convolutional Neural Networks (CNNs) have been one of the most influential recent developments in computer vision, particularly for categorization. There is an increasing demand for explainable AI as these systems are deployed in the…

Computer Vision and Pattern Recognition · Computer Science 2018-11-21 Tian Xu , Jiayu Zhan , Oliver G. B. Garrod , Philip H. S. Torr , Song-Chun Zhu , Robin A. A. Ince , Philippe G. Schyns

Molecular carriers represent an increasingly common strategy in the field of nanopore sensing to use secondary molecules to selectively report on the presence of target analytes in solution, allowing for sensitive assays of otherwise…

Biomolecules · Quantitative Biology 2023-05-10 Zachary Roelen , Vincent Tabard-Cossa

Using smart wearable devices to monitor patients electrocardiogram (ECG) for real-time detection of arrhythmias can significantly improve healthcare outcomes. Convolutional neural network (CNN) based deep learning has been used successfully…

Machine Learning · Computer Science 2021-09-07 Xiaolin Li , Rajesh Panicker , Barry Cardiff , Deepu John

This work exploits the zeptoliter sensing volume of electrolyte-filled nanopores to determine, simultaneously and in real time, the approximate shape, volume, charge, rotational diffusion coefficient, and dipole moment of individual…

Modeling the ion concentration profile in nanochannel plays an important role in understanding the electrical double layer and electroosmotic flow. Due to the non-negligible surface interaction and the effect of discrete solvent molecules,…

Machine Learning · Computer Science 2023-12-19 Zhonglin Cao , Yuyang Wang , Cooper Lorsung , Amir Barati Farimani

We investigate the feasibility of using deep learning techniques, in the form of a one-dimensional convolutional neural network (1D-CNN), for the extraction of signals from the raw waveforms produced by the individual channels of liquid…

Instrumentation and Detectors · Physics 2022-02-09 Lorenzo Uboldi , David Ruth , Michael Andrews , Michael H. L. S. Wang , Hans-Joachim Wenzel , Wanwei Wu , Tingjun Yang

Deep neural network is an effective choice to automatically recognize human actions utilizing data from various wearable sensors. These networks automate the process of feature extraction relying completely on data. However, various noises…

Signal Processing · Electrical Eng. & Systems 2021-01-05 Tanvir Mahmud , A. Q. M. Sazzad Sayyed , Shaikh Anowarul Fattah , Sun-Yuan Kung

A well-designed fine-grained categorization system usually has three contradictory requirements: accuracy (the ability to identify objects among subordinate categories); interpretability (the ability to provide human-understandable…

Computer Vision and Pattern Recognition · Computer Science 2016-10-05 Shaoli Huang , Dacheng Tao

Nanopore sequencing is an emerging DNA sequencing technology that has been proposed for use in DNA storage systems. We propose the noisy nanopore channel model for nanopore sequencing. This model captures duplications, inter-symbol…

Information Theory · Computer Science 2022-05-10 Brendon McBain , Emanuele Viterbo , James Saunderson

Convolutional neural networks (CNNs) are currently among the most widely-used deep neural network (DNN) architectures available and achieve state-of-the-art performance for many problems. Originally applied to computer vision tasks, CNNs…

Machine Learning · Computer Science 2024-02-29 Inés Gonzalez Pepe , Yohan Chatelain , Gregory Kiar , Tristan Glatard

In this paper, we propose a novel deep neural network framework embedded with low-level features (LCNN) for salient object detection in complex images. We utilise the advantage of convolutional neural networks to automatically learn the…

Computer Vision and Pattern Recognition · Computer Science 2015-08-18 Hongyang Li , Huchuan Lu , Zhe Lin , Xiaohui Shen , Brian Price

State-of-the-art methods for protein-protein interaction (PPI) extraction are primarily feature-based or kernel-based by leveraging lexical and syntactic information. But how to incorporate such knowledge in the recent deep learning methods…

Computation and Language · Computer Science 2017-06-08 Yifan Peng , Zhiyong Lu

Motivation: Drug discovery demands rapid quantification of compound-protein interaction (CPI). However, there is a lack of methods that can predict compound-protein affinity from sequences alone with high applicability, accuracy, and…

Biomolecules · Quantitative Biology 2020-12-17 Mostafa Karimi , Di Wu , Zhangyang Wang , Yang Shen

Advanced nanopore measurements allow structural probing of molecules with high spatial and temporal resolution. We report high signal-to-noise, 1-10 MHz bandwidth, translocation measurements of the multi-state folding of heme protein…

Biological Physics · Physics 2025-12-18 Kyril Kavetsky , Sabine Hong , Chih-Yuan Lin , Roger Yang , Marija Drndic