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With the advent of pretrained language models (LMs), increasing research efforts have been focusing on infusing commonsense and domain-specific knowledge to prepare LMs for downstream tasks. These works attempt to leverage knowledge graphs,…

Computation and Language · Computer Science 2023-05-16 Shangbin Feng , Zhaoxuan Tan , Wenqian Zhang , Zhenyu Lei , Yulia Tsvetkov

High-throughput phenotyping, the automated mapping of patient signs and symptoms to standardized ontology concepts, is essential to gaining value from electronic health records (EHR) in the support of precision medicine. Despite…

Artificial Intelligence · Computer Science 2024-06-24 Syed I. Munzir , Daniel B. Hier , Chelsea Oommen , Michael D. Carrithers

Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external…

Computation and Language · Computer Science 2025-02-20 Yucheng Shi , Tianze Yang , Canyu Chen , Quanzheng Li , Tianming Liu , Xiang Li , Ninghao Liu

Extracting structured information from clinical notes requires navigating a dense web of interdependent variables where the value of one attribute logically constrains others. Existing Large Language Model (LLM)-based extraction pipelines…

Incorporating factual knowledge into pre-trained language models (PLM) such as BERT is an emerging trend in recent NLP studies. However, most of the existing methods combine the external knowledge integration module with a modified…

Computation and Language · Computer Science 2022-05-06 Yinquan Lu , Haonan Lu , Guirong Fu , Qun Liu

Medical Large Language Models (LLMs) have demonstrated impressive performance on a wide variety of medical NLP tasks; however, there still lacks a LLM specifically designed for phenotyping identification and diagnosis in cancer domain.…

Computation and Language · Computer Science 2025-04-02 Mingchen Li , Jiatan Huang , Jeremy Yeung , Anne Blaes , Steven Johnson , Hongfang Liu , Hua Xu , Rui Zhang

Large language models (LLMs) have revolutionized various domains, yet their utility comes with significant challenges related to outdated or problematic knowledge embedded during pretraining. This paper addresses the challenge of modifying…

Computation and Language · Computer Science 2024-09-23 Akshaj Kumar Veldanda , Shi-Xiong Zhang , Anirban Das , Supriyo Chakraborty , Stephen Rawls , Sambit Sahu , Milind Naphade

Large language models (LLMs) have made significant progress in general-purpose natural language processing tasks. However, LLMs are still facing challenges when applied to domain-specific areas like telecommunications, which demands…

Computation and Language · Computer Science 2025-05-22 Dun Yuan , Hao Zhou , Di Wu , Xue Liu , Hao Chen , Yan Xin , Jianzhong , Zhang

We present EHRMIND, a practical recipe for adapting large language models (LLMs) to complex clinical reasoning tasks using reinforcement learning with verifiable rewards (RLVR). While RLVR has succeeded in mathematics and coding, its…

Computation and Language · Computer Science 2025-06-02 Jiacheng Lin , Zhenbang Wu , Jimeng Sun

Large language models (LLMs) have demonstrated significant potential in clinical decision support. Yet LLMs still suffer from hallucinations and lack fine-grained contextual medical knowledge, limiting their high-stake healthcare…

Computation and Language · Computer Science 2025-04-22 Pengcheng Jiang , Cao Xiao , Minhao Jiang , Parminder Bhatia , Taha Kass-Hout , Jimeng Sun , Jiawei Han

Large Language Models (LLMs), although powerful in general domains, often perform poorly on domain-specific tasks such as medical question answering (QA). In addition, LLMs tend to function as "black-boxes", making it challenging to modify…

Computation and Language · Computer Science 2024-08-19 Yucheng Shi , Shaochen Xu , Tianze Yang , Zhengliang Liu , Tianming Liu , Quanzheng Li , Xiang Li , Ninghao Liu

Large language models (LLMs) show promise for diagnostic reasoning but often lack reliable, knowledge grounded inference. Knowledge graphs (KGs), such as the Unified Medical Language System (UMLS), offer structured biomedical knowledge that…

Computation and Language · Computer Science 2025-09-24 Saksham Khatwani , He Cheng , Majid Afshar , Dmitriy Dligach , Yanjun Gao

Large language models (LLMs) have demonstrated remarkable capabilities across various NLP tasks. However, their computational costs are prohibitively high. To address this issue, previous research has attempted to distill the knowledge of…

Computation and Language · Computer Science 2024-03-12 Chengyuan Liu , Yangyang Kang , Fubang Zhao , Kun Kuang , Zhuoren Jiang , Changlong Sun , Fei Wu

Extracting structured medical insights from unstructured clinical text using Natural Language Processing (NLP) remains an open challenge in healthcare, particularly in non-English contexts where resources are scarce. This study presents a…

Artificial Intelligence · Computer Science 2025-11-21 Paulina Tworek , Miłosz Bargieł , Yousef Khan , Tomasz Pełech-Pilichowski , Marek Mikołajczyk , Roman Lewandowski , Jose Sousa

We introduce a novel large language model (LLM)-driven agent framework, which iteratively refines queries and filters contextual evidence by leveraging dynamically evolving knowledge. A defining feature of the system is its decoupling of…

Artificial Intelligence · Computer Science 2025-04-02 Seyoung Song

Large Language Models (LLMs) have demonstrated remarkable success in various tasks such as natural language understanding, text summarization, and machine translation. However, their general-purpose nature often limits their effectiveness…

Computation and Language · Computer Science 2025-09-03 Zirui Song , Bin Yan , Yuhan Liu , Miao Fang , Mingzhe Li , Rui Yan , Xiuying Chen

Large language models (LLMs) often exhibit limited performance on domain-specific tasks due to the natural disproportionate representation of specialized information in their training data and the static nature of these datasets. Knowledge…

Computation and Language · Computer Science 2025-09-30 Chaojun Nie , Jun Zhou , Guanxiang Wang , Shisong Wu , Zichen Wang

Knowledge graphs and large language models (LLMs) are key tools for biomedical knowledge integration and reasoning, facilitating structured organization of scientific articles and discovery of complex semantic relationships. However,…

Computation and Language · Computer Science 2025-04-01 Yichun Feng , Jiawei Wang , Ruikun He , Lu Zhou , Yixue Li

Emergency management urgently requires comprehensive knowledge while having a high possibility to go beyond individuals' cognitive scope. Therefore, artificial intelligence(AI) supported decision-making under that circumstance is of vital…

Computation and Language · Computer Science 2023-11-16 Minze Chen , Zhenxiang Tao , Weitong Tang , Tingxin Qin , Rui Yang , Chunli Zhu

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman
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