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Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

The field of healthcare has increasingly turned its focus towards Large Language Models (LLMs) due to their remarkable performance. However, their performance in actual clinical applications has been underexplored. Traditional evaluations…

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Global healthcare providers are exploring use of large language models (LLMs) to provide medical advice to the public. LLMs now achieve nearly perfect scores on medical licensing exams, but this does not necessarily translate to accurate…

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

The demand for psychological counselling has grown significantly in recent years, particularly with the global outbreak of COVID-19, which has heightened the need for timely and professional mental health support. Online psychological…

Computation and Language · Computer Science 2023-09-04 Tin Lai , Yukun Shi , Zicong Du , Jiajie Wu , Ken Fu , Yichao Dou , Ziqi Wang

Individuals are increasingly utilizing large language model (LLM)based tools for mental health guidance and crisis support in place of human experts. While AI technology has great potential to improve health outcomes, insufficient empirical…

Patient simulators are gaining traction in mental health training by providing scalable exposure to complex and sensitive patient interactions. Simulating depressed patients is particularly challenging, as safety constraints and high…

Computation and Language · Computer Science 2026-04-29 Nguyen Khoi Hoang , Shuhaib Mehri , Tse-An Hsu , Yi-Jyun Sun , Quynh Xuan Nguyen Truong , Khoa D Doan , Dilek Hakkani-Tür

Although Large Language Models (LLMs) have shown promising performance in healthcare-related applications, their deployment in the medical domain poses unique challenges of ethical, regulatory, and technical nature. In this study, we employ…

Computers and Society · Computer Science 2025-01-22 Giorgia Carra , Bogdan Kulynych , François Bastardot , Daniel E. Kaufmann , Noémie Boillat-Blanco , Jean Louis Raisaro

Generative Artificial Intelligence is set to revolutionize healthcare delivery by transforming traditional patient care into a more personalized, efficient, and proactive process. Chatbots, serving as interactive conversational models, will…

Understanding the conversation abilities of Large Language Models (LLMs) can help lead to its more cautious and appropriate deployment. This is especially important for safety-critical domains like mental health, where someone's life may…

Computation and Language · Computer Science 2024-03-18 Alexander Marrapese , Basem Suleiman , Imdad Ullah , Juno Kim

Accurate and verifiable large language model (LLM) simulations of human research subjects promise an accessible data source for understanding human behavior and training new AI systems. However, results to date have been limited, and few…

Human-Computer Interaction · Computer Science 2025-06-06 Jacy Reese Anthis , Ryan Liu , Sean M. Richardson , Austin C. Kozlowski , Bernard Koch , James Evans , Erik Brynjolfsson , Michael Bernstein

As large language models transition from text-based interfaces to audio interactions in clinical settings, they might introduce new vulnerabilities through paralinguistic cues in audio. We evaluated these models on 170 clinical cases, each…

Computation and Language · Computer Science 2025-11-11 Zhi Rui Tam , Yun-Nung Chen

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic…

Computation and Language · Computer Science 2026-01-08 Lecheng Gong , Weimin Fang , Ting Yang , Dongjie Tao , Chunxiao Guo , Peng Wei , Bo Xie , Jinqun Guan , Zixiao Chen , Fang Shi , Jinjie Gu , Junwei Liu

While LLMs have demonstrated remarkable capabilities in text generation and reasoning, their ability to simulate human decision-making -- particularly in political contexts -- remains an open question. However, modeling voter behavior…

Computation and Language · Computer Science 2025-04-11 Chenxiao Yu , Jinyi Ye , Yuangang Li , Zheng Li , Emilio Ferrara , Xiyang Hu , Yue Zhao

Large Language Model (LLM) personas with explicit specifications of attributes, background, and behavioural tendencies are increasingly used to simulate human conversations for tasks such as user modeling, social reasoning, and behavioural…

Computation and Language · Computer Science 2026-03-04 Eliseo Bao , Anxo Perez , Xi Wang , Javier Parapar

Matching patients to clinical trials is a key unsolved challenge in bringing new drugs to market. Today, identifying patients who meet a trial's eligibility criteria is highly manual, taking up to 1 hour per patient. Automated screening is…

Computation and Language · Computer Science 2024-04-11 Michael Wornow , Alejandro Lozano , Dev Dash , Jenelle Jindal , Kenneth W. Mahaffey , Nigam H. Shah

Automated clinical text anonymization has the potential to unlock the widespread sharing of textual health data for secondary usage while assuring patient privacy and safety. Despite the proposal of many complex and theoretically successful…

Computation and Language · Computer Science 2024-06-05 David Pissarra , Isabel Curioso , João Alveira , Duarte Pereira , Bruno Ribeiro , Tomás Souper , Vasco Gomes , André V. Carreiro , Vitor Rolla

Mental health challenges are rising globally, while traditional support services face limited availability and high costs. Large language models offer potential for conversational support, but often lack personalization, empathy, and…

Human-Computer Interaction · Computer Science 2026-04-24 Truong Le Minh Toan , Dieu Bang Mach , Tan Duy Le , Nguyen Tan Viet Tuyen

Discharge communication is a critical yet underexplored component of patient care, where the goal shifts from diagnosis to education. While recent large language model (LLM) benchmarks emphasize in-visit diagnostic reasoning, they fail to…

Computation and Language · Computer Science 2025-09-22 Zonghai Yao , Michael Sun , Won Seok Jang , Sunjae Kwon , Soie Kwon , Hong Yu
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