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Hepatocellular carcinoma (HCC) is a common type of liver cancer whose early-stage diagnosis is a common challenge, mainly due to the manual assessment of hematoxylin and eosin-stained whole slide images, which is a time-consuming process…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Ajinkya Deshpande , Deep Gupta , Ankit Bhurane , Nisha Meshram , Sneha Singh , Petia Radeva

Transformers are very powerful tools for a variety of tasks across domains, from text generation to image captioning. However, transformers require substantial amounts of training data, which is often a challenge in biomedical settings,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Andrew Kean Gao

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

Colorectal liver metastases (CRLM) are a major cause of cancer-related mortality, and reliable detection on CT remains challenging in multi-centre settings. We developed a foundation model-based AI pipeline for patient-level classification…

Hyperspectral image classification, a task that assigns pre-defined classes to each pixel in a hyperspectral image of remote sensing scenes, often faces challenges due to the neglect of correlations between spectrally similar pixels. This…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Peifu Liu , Tingfa Xu , Jie Wang , Huan Chen , Huiyan Bai , Jianan Li

Prostate cancer is the most common noncutaneous cancer in the world. Recently, multi-modality transrectal ultrasound (TRUS) has increasingly become an effective tool for the guidance of prostate biopsies. With the aim of effectively…

Image and Video Processing · Electrical Eng. & Systems 2024-02-20 Hong Wu , Juan Fu , Hongsheng Ye , Yuming Zhong , Xuebin Zhou , Jianhua Zhou , Yi Wang

Hyperspectral image classification demands spatially coherent predictions and precise boundary delineation. Yet prevailing superpixel-based methods face an inherent contradiction: clustering aggregates similar pixels into regions, but the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Peifu Liu , Tingfa Xu , Jie Wang , Huan Chen , Huiyan Bai , Jianan Li

Automated classification of cancer pathology reports can extract information from unstructured reports and categorize each report into structured diagnosis and severity categories. Thus, such system can reduce the burden for populating…

The pancreatic disease taxonomy includes ten types of masses (tumors or cysts)[20,8]. Previous work focuses on developing segmentation or classification methods only for certain mass types. Differential diagnosis of all mass types is…

Image and Video Processing · Electrical Eng. & Systems 2020-12-10 Tianyi Zhao , Kai Cao , Jiawen Yao , Isabella Nogues , Le Lu , Lingyun Huang , Jing Xiao , Zhaozheng Yin , Ling Zhang

For diagnosing melanoma, hematoxylin and eosin (H&E) stained tissue slides remains the gold standard. These images contain quantitative information in different magnifications. In the present study, we investigated whether deep…

Tissues and Organs · Quantitative Biology 2019-04-15 Peizhen Xie , Ke Zuo , Yu Zhang , Fangfang Li , Mingzhu Yin , Kai Lu

Multiple instance learning (MIL) has shown significant promise in histopathology whole slide image (WSI) analysis for cancer diagnosis and prognosis. However, the inherent spatial heterogeneity of WSIs presents critical challenges, as…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Junjian Li , Jin Liu , Hulin Kuang , Hailin Yue , Mengshen He , Jianxin Wang

The distribution and appearance of nuclei are essential markers for the diagnosis and study of cancer. Despite the importance of nuclear morphology, there is a lack of large scale, accurate, publicly accessible nucleus segmentation data. To…

Image and Video Processing · Electrical Eng. & Systems 2020-12-02 Le Hou , Rajarsi Gupta , John S. Van Arnam , Yuwei Zhang , Kaustubh Sivalenka , Dimitris Samaras , Tahsin M. Kurc , Joel H. Saltz

In recent years, a standard computational pathology workflow has emerged where whole slide images are cropped into tiles, these tiles are processed using a foundation model, and task-specific models are built using the resulting…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Eric Zimmermann , Julian Viret , Michal Zelechowski , James Brian Hall , Neil Tenenholtz , Adam Casson , George Shaikovski , Eugene Vorontsov , Siqi Liu , Kristen A Severson

An increasing number of public datasets have shown a marked impact on automated organ segmentation and tumor detection. However, due to the small size and partially labeled problem of each dataset, as well as a limited investigation of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Jie Liu , Yixiao Zhang , Jie-Neng Chen , Junfei Xiao , Yongyi Lu , Bennett A. Landman , Yixuan Yuan , Alan Yuille , Yucheng Tang , Zongwei Zhou

Colorectal cancer remains a major global health concern, with early detection being pivotal for improving patient outcomes. In this study, we leveraged high throughput methylation profiling of cellfree DNA to identify and validate…

Genomics · Quantitative Biology 2025-05-19 Kartavya Mathur , Shipra Jain , Nisha Bajiya , Nishant Kumar , Gajendra P. S. Raghava

Background and Purpose: Colorectal cancer is a common fatal malignancy, the fourth most common cancer in men, and the third most common cancer in women worldwide. Timely detection of cancer in its early stages is essential for treating the…

Colorectal cancer is the third-most common cancer in the Western Hemisphere. The segmentation of colorectal and colorectal cancer by computed tomography is an urgent problem in medicine. Indeed, a system capable of solving this problem will…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 I. M. Chernenkiy , Y. A. Drach , S. R. Mustakimova , V. V. Kazantseva , N. A. Ushakov , S. K. Efetov , M. V. Feldsherov

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

The recent surge in performance for image analysis of digitised pathology slides can largely be attributed to the advances in deep learning. Deep models can be used to initially localise various structures in the tissue and hence facilitate…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Shan E Ahmed Raza , Fayyaz Minhas , David Snead , Nasir Rajpoot

Data curation is the problem of how to collect and organize samples into a dataset that supports efficient learning. Despite the centrality of the task, little work has been devoted towards a large-scale, systematic comparison of various…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Benjamin Feuer , Jiawei Xu , Niv Cohen , Patrick Yubeaton , Govind Mittal , Chinmay Hegde