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Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Colorectal cancer (CRC) is a leading worldwide cause of cancer-related mortality, and the role of prompt precise detection is of paramount interest in improving patient outcomes. Conventional diagnostic methods such as colonoscopy and…

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

Multi-class colorectal tissue classification is a challenging problem that is typically addressed in a setting, where it is assumed that ample amounts of training data is available. However, manual annotation of fine-grained colorectal…

Colorectal cancer (CRC) is one of the most common types of cancer with a high mortality rate. Colonoscopy is the preferred procedure for CRC screening and has proven to be effective in reducing CRC mortality. Thus, a reliable computer-aided…

Accurate localization of tumor regions from hematoxylin and eosin-stained whole-slide images is fundamental for translational research including spatial analysis, molecular profiling, and tissue architecture investigation. However, deep…

The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified PLCs on routine-stained biopsies using a weakly supervised…

The grade of clear cell renal cell carcinoma (ccRCC) is a critical prognostic factor, making ccRCC nuclei grading a crucial task in RCC pathology analysis. Computer-aided nuclei grading aims to improve pathologists' work efficiency while…

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Correct treatment of urothelial carcinoma patients is dependent on accurate grading and staging of the cancer tumour. This is determined manually by a pathologist by examining the histological whole-slide images (WSI). The large size of…

Oral Squamous Cell Carcinoma (OSCC) is a prevalent and aggressive malignancy where deep learning-based computer-aided diagnosis and prognosis can enhance clinical assessments.However, existing publicly available OSCC datasets often suffer…

Circulating Tumor Cells (CTCs) bear great promise as biomarkers in tumor prognosis. However, the process of identification and later enumeration of CTCs require manual labor, which is error-prone and time-consuming. The recent developments…

Molecular subtypes of colorectal cancer (CRC) significantly influence treatment decisions. While convolutional neural networks (CNNs) have recently been introduced for automated CRC subtype identification using H&E stained histopathological…

Numerous deep learning-based solutions have been proposed for histopathological image analysis over the past years. While they usually demonstrate exceptionally high accuracy, one key question is whether their precision might be affected by…

Clinical cystoscopy, the current standard for bladder cancer diagnosis, suffers from significant reliance on physician expertise, leading to variability and subjectivity in diagnostic outcomes. There is an urgent need for objective,…

Renal cell carcinoma (RCC) is the most common renal cancer in adults. The histopathologic classification of RCC is essential for diagnosis, prognosis, and management of patients. Reorganization and classification of complex histologic…

Accurate detection of cancer tissue regions (CTR) enables deeper analysis of the tumor microenvironment and offers crucial insights into treatment response. Traditional CTR detection methods, which typically rely on the rich cellular…

Medical professionals, especially those in training, often depend on visual reference materials to support an accurate diagnosis and develop pattern recognition skills. However, existing resources may lack the diversity and accessibility…

Colonoscopy screening effectively identifies and removes polyps before they progress to colorectal cancer (CRC), but current follow-up guidelines rely primarily on histopathological features, overlooking other important CRC risk factors.…

Automating tissue segmentation and tumor detection in histopathology images of colorectal cancer (CRC) is an enabler for faster diagnostic pathology workflows. At the same time it is a challenging task due to low availability of public…