Related papers: Variational Percolation Bounds for Cellular Membra…
We study the permeability and selectivity (`permselectivity') of model membranes made of polydisperse polymer networks for molecular penetrant transport, using coarse-grained, implicit-solvent computer simulations. The permeability…
The migratory dynamics of cells can be influenced by the complex micro-environment through which they move. It remains unclear how the motility machinery of confined cells responds and adapts to their micro-environment. Here, we propose a…
We study a class of dynamical multi-commodity flow networks in transportation networks. These are modeled as dynamical systems describing the evolution of the densities of a number of different commodities across the cells of a…
From the perspective of physical properties, the cell membrane is an exotic two-dimensional material that has a dual nature: it exhibits characteristics of fluids, i.e., lipid molecules show lateral diffusion, while also demonstrating…
How do solute concentration and molecular chemistry govern the transition from membrane saturation to destabilization? We address this using microsecond-scale molecular dynamics simulations of dipalmitoylphosphatidylcholine (DPPC) bilayers…
The spatial organization of a passive scalar plume originating from a point source in a turbulent boundary layer is studied to understand its meandering characteristics. We focus shortly downstream of the isokinetic injection ($1.5\le…
This paper studies the capacity of massive random-access cellular networks, modeled as a MIMO fading channel with an infinite number of interfering cells. To characterize the symmetric sum rate of the network, a random-coding argument is…
We develop an exact electrostatic formulation for a finite-length conducting cylindrical shell of finite thickness separating two dielectric media with arbitrary permittivity contrast. The boundary-value problem is reduced to a coupled…
We develop a quantitative framework to determine the minimal periodic supercell required for representative simulations of capillarity-screened Darcy flow in stationary random, polydisperse granular media. The microstructure is…
Biological systems are governed by coupled interactions between intracellular metabolism and bioreactor operation that span multiple time scales. Constraint-based metabolic models are widely used to describe intracellular metabolism, but…
In this work we present and discuss theoretical models of redox molecular junctions that account for recent observations of nonlinear charge transport phenomena, such as hysteresis and hysteretic negative differential resistance (NDR). A…
Migratory and tissue resident cells exhibit highly branched morphologies to perform their function and to adapt to the microenvironment. Immune cells, for example, display transient branched shapes while exploring the surrounding tissues.…
Electrochemical phenomena in biology often unfold in confined geometries where micrometer- to millimeter-scale domains coexist with nanometer-scale interfacial diffuse charge layers. We analyze a model lipid membrane-electrolyte system…
We consider the influence of disorder on the non-equilibrium steady state of a minimal model for intracellular transport. In this model particles move unidirectionally according to the \emph{totally asymmetric exclusion process} (TASEP) and…
The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…
A phase diagram for a one dimensional fiber bundle model is constructed with a continuous variation in two parameters guiding dynamics of the model: strength of disorder and system size. We monitor the successive events of fiber rupture in…
We study a model problem on the filtration of a conducting fluid through a porous layer. A porous medium is presented as an assemblage of identical spherical cells. Each cell consists of a porous core and liquid shell. We show the…
We derive exact expressions for so-called ``void'' bounds on the trapping constant $\gamma$ and fluid permeability $k$ for coated-spheres and coated-cylinders models of porous media. We find that in some cases the bounds are optimal, i.e.,…
The light-driven reactions of photosynthesis, as well as the mitochondrial power supply, are hosted within specialized membranes containing a high fraction of redoxactive lipids. Protein mobility and diffusion of redox lipids is believed to…
We consider cumulative merging percolation (CMP), a long-range percolation process describing the iterative merging of clusters in networks, depending on their mass and mutual distance. For a specific class of CMP processes, which…