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Intercellular exchange networks are essential for the adaptive capabilities of populations of cells. While diffusional exchanges have traditionally been difficult to map, recent advances in nanotechnology enable precise probing of exchange…

Statistical Mechanics · Physics 2024-12-13 Luís C. F. Latoski , Andrea De Martino , Daniele De Martino

We investigate the outflux of ions through the channels in a cell membrane. The channels undergo an open/close cycle according to a periodic schedule. Our study is based both on theoretical considerations relying on homogenization theory,…

Analysis of PDEs · Mathematics 2014-11-21 D. Andreucci , D. Bellaveglia , E. N. M. Cirillo

Metabolic substrates, such as oxygen and glucose, are rapidly delivered to the cell through filtration across microvessels walls. Modelling this important process is complicated by the coupling between flow and transport equations, which…

Subcellular Processes · Quantitative Biology 2013-08-12 Laura Facchini , Alberto Bellin , Eleuterio F. Toro

Restrictions to molecular motion by barriers (membranes) are ubiquitous in biological tissues, porous media and composite materials. A major challenge is to characterize the microstructure of a material or an organism nondestructively using…

Soft Condensed Matter · Physics 2011-03-11 Dmitry S. Novikov , Els Fieremans , Jens H. Jensen , Joseph A. Helpern

We find a statistical mechanism that can adjust orientations of intracellular filaments to cell geometry in absence of organizing centers. The effect is based on random and isotropic filament (de-)polymerization dynamics and is independent…

Biological Physics · Physics 2015-05-28 Philip Greulich , Ludger Santen

The Poisson-Nernst-Planck (PNP) diffusional model for the immittance or impedance spectroscopy response of an electrolytic cell in a finite-length situation is extended to a general framework. In this new formalism, the bulk behavior of the…

A model for ionic and electronic grain boundary transport through thin films, scales or membranes with columnar grain structure is introduced. The grain structure is idealized as a lattice of identical hexagonal cells - a honeycomb pattern.…

Materials Science · Physics 2017-05-05 M. P. Tautschnig , N. M. Harrison , M. W. Finnis

We develop a mesoscopic approach to model the non-equilibrium behavior of membranes at the cellular scale. Relying on lattice Boltzmann methods, we develop a solution procedure to recover the Nernst-Planck equations and Gauss's law. A…

Mesoscale and Nanoscale Physics · Physics 2023-02-22 James E. McClure , Zhe Li

Many biological tissues feature a heterogeneous network of fibers whose tensile and bending rigidity contribute substantially to these tissues' elastic properties. Rigidity percolation has emerged as a important paradigm for relating these…

In the rapidly rotating limit, we derive a balanced set of reduced equations governing the strongly nonlinear development of the convective wall-mode instability in the interior of a general container. The model illustrates that wall-mode…

A general framework for determining fundamental bounds in nanophotonics is introduced in this paper. The theory is based on convex optimization of dual problems constructed from operators generated by electromagnetic integral equations. The…

Optics · Physics 2021-06-23 M. Gustafsson , K. Schab , L. Jelinek , M. Capek

Biomolecular condensates organize biochemical processes by spatially concentrating molecules while allowing for dynamic exchange with their surroundings. However, transport across their interface can be strongly attenuated, leading to…

Biological Physics · Physics 2026-03-27 Oihan Joyot , Zoé Ferrand , Fernando Muzzopappa , Pierre Weiss , Fabian Erdel

Cellular morphodynamics requires solving systems of coupled partial differential equations on moving bulk and surface domains, where advection-dominant transport, structure preservation, and severe mesh distortions make robust simulation…

Numerical Analysis · Mathematics 2026-01-12 Alessandro Contri , André Massing , Padmini Rangamani

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

The flow of micropolar fluid through a membrane modeled as a swarm of solid cylindrical particles with porous layer using the cell model technique is considered. The flow is directed perpendicular to the axis of the cylinders. Boundary…

Fluid Dynamics · Physics 2019-09-04 D. Yu. Khanukaeva , A. N. Filippov , P. K. Yadav , A. Tiwari

Weak multiplex percolation generalizes percolation to multi-layer networks, represented as networks with a common set of nodes linked by multiple types (colors) of edges. We report a novel discontinuous phase transition in this problem.…

Physics and Society · Physics 2022-03-15 R. A. da Costa , G. J. Baxter , S. N. Dorogovtsev , J. F. F. Mendes

This paper is devoted to the variational derivation of reduced models for elastic membranes with fracture under constraints on the determinant of the deformation gradient. We consider two physically relevant settings: the…

Analysis of PDEs · Mathematics 2026-03-24 Nicola Pio Melillo , Dario Reggiani

The diffusive transport of biased Brownian particles in a two-dimensional symmetric channel is investigated numerically considering both the no-flow and the reflection boundary conditions at the channel boundaries. Here, the geometrical…

Soft Condensed Matter · Physics 2019-09-10 Narender Khatri , P. S. Burada

Membrane pores are implicated in several critical functions, including cell fusion and the transport of signaling molecules for intercellular communication. However, these structural features are often difficult to probe directly. Droplet…

Soft Condensed Matter · Physics 2025-11-13 Nivedina A. Sarma , David A. King , Xuefei Wu , Brett A. Helms , Paul D. Ashby , Thomas P. Russell , Ahmad K. Omar

The diffusion of molecules (penetrants) of variable size, shape, and chemistry through dense crosslinked polymer networks is a fundamental scientific problem that is broadly relevant in materials, polymer, physical and biological chemistry.…

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