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Sequencing of PCR amplicons generated using degenerate primers (typically targeting a region of the 16S ribosomal gene) is widely used in metagenomics to profile the taxonomic composition of complex microbial samples. To reduce taxonomic…

Genomics · Quantitative Biology 2025-11-04 Rye Howard-Stone , Ion Mandiou

ALDO2 is a multi-function, adjustable, low dropout linear regulator designed in onsemi I3T80 0.35~$\mu$m HV CMOS technology for use in HEP detectors that adopt silicon photomultipliers (SiPMs). The chip features four independent regulators,…

Instrumentation and Detectors · Physics 2022-08-31 Paolo Carniti , Claudio Gotti , Gianluigi Pessina

Heterogeneous computers integrate general-purpose host processors with domain-specific accelerators to combine versatility with efficiency and high performance. To realize the full potential of heterogeneous computers, however, many…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-01-12 Andreas Kurth , Björn Forsberg , Luca Benini

The Analog Pipeline Chip (APC) is a low noise, low power readout chip for silicon micro strip detectors with 128 channels containing an analog pipeline of 32 buffers depth. The chip has been designed for operation at HERA with a power…

High Energy Physics - Experiment · Physics 2011-07-19 Michael Hilgers , Roland Horisberger

Many modern video processing pipelines rely on edge-aware (EA) filtering methods. However, recent high-quality methods are challenging to run in real-time on embedded hardware due to their computational load. To this end, we propose an…

Image and Video Processing · Electrical Eng. & Systems 2017-11-16 Manuel Eggimann , Christelle Gloor , Florian Scheidegger , Lukas Cavigelli , Michael Schaffner , Aljosa Smolic , Luca Benini

Feature fusion plays a pivotal role in achieving high performance in vision models, yet existing attention-based fusion techniques often suffer from substantial computational overhead and implementation complexity, particularly in…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Junyi Hu , Tian Bai , Fengyi Wu , Zhenming Peng , Yi Zhang

The overexpression of the human epidermal growth factor receptor 2 (HER2) in breast cells is a key driver of HER2-positive breast cancer, a highly aggressive subtype requiring precise diagnosis and targeted therapy. Immunohistochemistry…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Sara Rehmat , Hafeez Ur Rehman , Byeong-Gwon Kang , Sarra Ayouni , Yunyoung Nam

As the successor of H.265/HEVC, the new versatile video coding standard (H.266/VVC) can provide up to 50% bitrate saving with the same subjective quality, at the cost of increased decoding complexity. To accelerate the application of the…

Image and Video Processing · Electrical Eng. & Systems 2021-03-08 Yiming Li , Shan Liu , Yu Chen , Yushan Zheng , Sijia Chen , Bin Zhu , Jian Lou

Increasing the efficiency and reducing the footprint of on-chip photodetectors enables dense optical interconnects for emerging computational and sensing applications. Avalanche photodetectors (APD) are currently the dominating on-chip…

Instrumentation and Detectors · Physics 2023-11-08 Lining Liu , Simone Bianconi , Skylar Wheaton , Nathaniel Coirier , Farah Fahim , Hooman Mohseni

Modern processors have instructions to process 16 bytes or more at once. These instructions are called SIMD, for single instruction, multiple data. Recent advances have leveraged SIMD instructions to accelerate parsing of common Internet…

Data Structures and Algorithms · Computer Science 2025-06-05 Daniel Lemire

A front-end readout electronics system has been developed for silicon strip detectors. The system uses an application specific integrated circuit (ASIC) ATHED to realize multi-channel E&T measurement. The slow control of ASIC chips is…

Instrumentation and Detectors · Physics 2011-06-13 Yi Qian , Hong Su , Jie Kong , Cheng-Fu Dong , Xiao-Li Ma , Xiao-Gang Li

We present the first results from the HPSoC ASIC designed for readout of Ultra-fast Silicon Detectors. The 4-channel ASIC manufactured in 65 nm CMOS by TSMC has been optimized for 50 um thick AC-LGAD. The evaluation of the analog front end…

This living paper reviews the present High Performance Computing (HPC) capabilities of the Tinker-HP molecular modeling package. We focus here on the reference, double precision, massively parallel molecular dynamics engine present in…

Mathematical Software · Computer Science 2024-01-11 Luc-Henri Jolly , Alejandro Duran , Louis Lagardère , Jay W. Ponder , Pengyu Ren , Jean-Philip Piquemal

Genomic sequence alignment is an important research topic in bioinformatics and continues to attract significant efforts. As genomic data grow exponentially, however, most of alignment methods face challenges due to their huge computational…

Computational Engineering, Finance, and Science · Computer Science 2018-06-07 Hanyu Jiang , Narayan Ganesan , Yu-Dong Yao

The use of silicon photomultipliers (SiPMs) to detect light signals in highly radioactive environments presents several challenges, particularly due to their sensitivity on radiation, temperature, and overvoltage, requiring a proper…

Instrumentation and Detectors · Physics 2024-07-09 Paolo Carniti , Claudio Gotti , Gianluigi Pessina

The wav2vec 2.0 and integrated spectro-temporal graph attention network (AASIST) based countermeasure achieves great performance in speech anti-spoofing. However, current spoof speech detection systems have fixed training and evaluation…

Audio and Speech Processing · Electrical Eng. & Systems 2024-01-05 Yuxiang Zhang , Jingze Lu , Zengqiang Shang , Wenchao Wang , Pengyuan Zhang

Recent advances in unsupervised speech representation learning discover new approaches and provide new state-of-the-art for diverse types of speech processing tasks. This paper presents an investigation of using wav2vec 2.0 deep speech…

Attention-based encoder-decoder, e.g. transformer and its variants, generates the output sequence in an autoregressive (AR) manner. Despite its superior performance, AR model is computationally inefficient as its generation requires as many…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-27 Keyu An , Zerui Li , Zhifu Gao , Shiliang Zhang

Amplitude-coherent (AC) detection is an efficient detection technique that can simplify the receiver design while providing reliable symbol error rate (SER). Therefore, this work considers AC detector design and SER analysis using M-ary…

Information Theory · Computer Science 2019-02-06 Mohammad Al-Jarrah , Ki-Hong Park , Arafat Al-Dweik , Mohamed-Slim Alouini

Real-time unmanned aerial vehicle (UAV) acoustic detection at the edge demands low-latency inference under strict power and hardware limits. This paper presents SHIELD8-UAV, a sequential 8-bit hardware implementation of a precision-aware 1D…

Hardware Architecture · Computer Science 2026-03-03 Susmita Ghanta , Karan Nathwani , Rohit Chaurasiya
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