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Numerous studies have established that estimated brain age, as derived from statistical models trained on healthy populations, constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-02 Xinyang Feng , Zachary C. Lipton , Jie Yang , Scott A. Small , Frank A. Provenzano

Brain age prediction based on neuroimaging data could help characterize both the typical brain development and neuropsychiatric disorders. Pattern recognition models built upon functional connectivity (FC) measures derived from resting…

Computer Vision and Pattern Recognition · Computer Science 2018-01-15 Hongming Li , Theodore D. Satterthwaite , Yong Fan

The aging society urgently requires scalable methods to monitor cognitive decline and identify social and psychological factors indicative of dementia risk in older adults. Our machine learning (ML) models captured facial, acoustic,…

Machine learning analysis of neuroimaging data can accurately predict chronological age in healthy people and deviations from healthy brain ageing have been associated with cognitive impairment and disease. Here we sought to further…

Timely implementation of interventions to slow cognitive decline among older adults requires accurate monitoring to detect changes in cognitive function. Data gathered using wearable devices that can continuously monitor factors known to be…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Collin Sakal , Tingyou Li , Juan Li , Xinyue Li

Brain age estimation from Magnetic Resonance Images (MRI) derives the difference between a subject's biological brain age and their chronological age. This is a potential biomarker for neurodegeneration, e.g. as part of Alzheimer's disease.…

Computer Vision and Pattern Recognition · Computer Science 2020-10-02 Kyriaki-Margarita Bintsi , Vasileios Baltatzis , Arinbjörn Kolbeinsson , Alexander Hammers , Daniel Rueckert

We build on the empirical finding that a human being's mental age is normally distributed around the chronological age. This opposes the frequent societal assumption "mental = chronological" which is known to be false in general but…

Applications · Statistics 2021-07-30 Patrick A. Haas

We present a practical health-theme machine learning (ML) application concerning `AI for social good' domain for `Producing Good Outcomes' track. In particular, the solution is concerning the problem of a potential elderly adult dementia…

Neurons and Cognition · Quantitative Biology 2019-11-28 Tomasz M. Rutkowski , Masato S. Abe , Marcin Koculak , Mihoko Otake-Matsuura

Over the years, Machine Learning models have been successfully employed on neuroimaging data for accurately predicting brain age. Deviations from the healthy brain aging pattern are associated to the accelerated brain aging and brain…

Image and Video Processing · Electrical Eng. & Systems 2023-06-23 M. Tanveer , M. A. Ganaie , Iman Beheshti , Tripti Goel , Nehal Ahmad , Kuan-Ting Lai , Kaizhu Huang , Yu-Dong Zhang , Javier Del Ser , Chin-Teng Lin

The Clock-Drawing test is a well known and widely used neuropsychological metric to assess basic cognitive function. My objective is to combine methods of machine learning in computer vision and image analysis to predict a subject's level…

Neurons and Cognition · Quantitative Biology 2023-05-02 Luzhou Zhang

Background and Objectives: This paper focuses on using AI to assess the cognitive function of older adults with mild cognitive impairment or mild dementia using physiological data provided by a wearable device. Cognitive screening tools are…

Neurons and Cognition · Quantitative Biology 2025-11-10 Assma Habadi , Milos Zefran , Lijuan Yin , Woojin Song , Maria Caceres , Elise Hu , Naoko Muramatsu

The population is aging, and becoming more tech-savvy. The United Nations predicts that by 2050, one in six people in the world will be over age 65 (up from one in 11 in 2019), and this increases to one in four in Europe and Northern…

Computation and Language · Computer Science 2021-10-19 Kathleen C. Fraser , Majid Komeili

The study uses the British National Corpus 2014, a large sample of contemporary spoken British English, to investigate language patterns across different age groups. Our research attempts to explore how language patterns vary between…

Computation and Language · Computer Science 2025-06-24 MingZe Tang

Observation is an essential tool for understanding and studying human behavior and mental states. However, coding human behavior is a time-consuming, expensive task, in which reliability can be difficult to achieve and bias is a risk.…

Computer Vision and Pattern Recognition · Computer Science 2022-07-12 Flavia D. Frumosu , Nicole N. Lønfeldt , A. -R. Cecilie Mora-Jensen , Sneha Das , Nicklas Leander Lund , A. Katrine Pagsberg , Line K. H. Clemmensen

Cognitive impairments in older adults represent a significant public health concern, necessitating accurate diagnostic and monitoring strategies. In this study, the principal cognitive and neuropsychological evaluations employed for the…

Neurons and Cognition · Quantitative Biology 2024-02-23 Chuang Li , Rubing Lin , Yantong Liu , Yichen Wei

Brain age is the estimate of biological age derived from neuroimaging datasets using machine learning algorithms. Increasing brain age with respect to chronological age can reflect increased vulnerability to neurodegeneration and cognitive…

Quantitative Methods · Quantitative Biology 2024-02-13 Saurabh Sihag , Gonzalo Mateos , Alejandro Ribeiro

Early detection is crucial for timely intervention aimed at preventing and slowing the progression of neurocognitive disorder (NCD), a common and significant health problem among the aging population. Recent evidence has suggested that…

Computation and Language · Computer Science 2025-06-11 Yuejiao Wang , Xianmin Gong , Xixin Wu , Patrick Wong , Hoi-lam Helene Fung , Man Wai Mak , Helen Meng

The majority of research in computational psycholinguistics has concentrated on the processing of words. This study introduces innovative methods for computing sentence-level metrics using multilingual large language models. The metrics…

Computation and Language · Computer Science 2024-04-17 Kun Sun , Rong Wang

Neuroimaging-driven prediction of brain age, defined as the predicted biological age of a subject using only brain imaging data, is an exciting avenue of research. In this work we seek to build models of brain age based on functional…

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