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In computer-aided diagnosis (CAD) focused on microscopy, denoising improves the quality of image analysis. In general, the accuracy of this process may depend both on the experience of the microscopist and on the equipment sensitivity and…

Image and Video Processing · Electrical Eng. & Systems 2021-05-04 Fabio Hernán Gil Zuluaga , Francesco Bardozzo , Jorge Iván Ríos Patiño , Roberto Tagliaferri

We present a deep neural network to reduce coherent noise in three-dimensional quantitative phase imaging. Inspired by the cycle generative adversarial network, the denoising network was trained to learn a transform between two image…

While molecular pre-training has shown great potential in enhancing drug discovery, the lack of a solid physical interpretation in current methods raises concerns about whether the learned representation truly captures the underlying…

Biomolecules · Quantitative Biology 2023-11-07 Yuyan Ni , Shikun Feng , Wei-Ying Ma , Zhi-Ming Ma , Yanyan Lan

Noisy images are a challenge to image compression algorithms due to the inherent difficulty of compressing noise. As noise cannot easily be discerned from image details, such as high-frequency signals, its presence leads to extra bits…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Yuxin Xie , Li Yu , Farhad Pakdaman , Moncef Gabbouj

Video denoising aims at removing noise from videos to recover clean ones. Some existing works show that optical flow can help the denoising by exploiting the additional spatial-temporal clues from nearby frames. However, the flow estimation…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Jiezhang Cao , Qin Wang , Jingyun Liang , Yulun Zhang , Kai Zhang , Radu Timofte , Luc Van Gool

Supervised deep learning methods typically require large datasets and high-quality labels to achieve reliable predictions. However, their performance often degrades when trained on imperfect labels. To address this challenge, we propose a…

Geophysics · Physics 2025-11-20 Yang Cui , Denis Anikiev , Umair Bin Waheed , Yangkang Chen

Removal or cancellation of noise has wide-spread applications for imaging and acoustics. In every-day-life applications, denoising may even include generative aspects, which are unfaithful to the ground truth. For scientific use, however,…

Deep learning (DL) has arguably emerged as the method of choice for the detection and segmentation of biological structures in microscopy images. However, DL typically needs copious amounts of annotated training data that is for biomedical…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Mangal Prakash , Tim-Oliver Buchholz , Manan Lalit , Pavel Tomancak , Florian Jug , Alexander Krull

Medical image acquisition is often intervented by unwanted noise that corrupts the information content. This paper introduces an unsupervised medical image denoising technique that learns noise characteristics from the available images and…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Swati Rai , Jignesh S. Bhatt , S. K. Patra

Scanning microscopy systems, such as confocal and multiphoton microscopy, are powerful imaging tools for probing deep into biological tissue. However, scanning systems have an inherent trade-off between acquisition time, field of view,…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Cassandra Tong Ye , Jiashu Han , Kunzan Liu , Anastasios Angelopoulos , Linda Griffith , Kristina Monakhova , Sixian You

This paper proposes a novel method for automatic MRI denoising that exploits last advances in deep learning feature regression and self-similarity properties of the MR images. The proposed method is a two-stage approach. In the first stage,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-19 Jose V. Manjon , Pierrick Coupe

Magnetic Resonance Imaging (MRI), including diffusion MRI (dMRI), serves as a ``microscope'' for anatomical structures and routinely mitigates the influence of low signal-to-noise ratio scans by compromising temporal or spatial resolution.…

Image and Video Processing · Electrical Eng. & Systems 2025-03-11 Chenxu Wu , Qingpeng Kong , Zihang Jiang , S. Kevin Zhou

Large amount of image denoising literature focuses on single channel images and often experimentally validates the proposed methods on tens of images at most. In this paper, we investigate the interaction between denoising and…

Computer Vision and Pattern Recognition · Computer Science 2017-04-06 Jiqing Wu , Radu Timofte , Zhiwu Huang , Luc Van Gool

Fully supervised deep-learning based denoisers are currently the most performing image denoising solutions. However, they require clean reference images. When the target noise is complex, e.g. composed of an unknown mixture of primary…

Image and Video Processing · Electrical Eng. & Systems 2020-08-03 Florian Lemarchand , Erwan Nogues , Maxime Pelcat

A flexible discriminative image denoiser is introduced in which multi-task learning methods are applied to a densoising FCN based on U-Net. The activations of the U-Net model are modified by affine transforms that are a learned function of…

Image and Video Processing · Electrical Eng. & Systems 2020-11-26 Anthony Kelly

Endoscopes featuring a miniaturized design have significantly enhanced operational flexibility, portability, and diagnostic capability while substantially reducing the invasiveness of medical procedures. Recently, single-use endoscopes…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Yu Xing , Shishi Huang , Meng Lv , Guo Chen , Huailiang Wang , Lingzhi Sui

Despite the indispensable role of X-ray computed tomography (CT) in diagnostic medicine field, the associated ionizing radiation is still a major concern considering that it may cause genetic and cancerous diseases. Decreasing the exposure…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

We demonstrate that a deep neural network can significantly improve optical microscopy, enhancing its spatial resolution over a large field-of-view and depth-of-field. After its training, the only input to this network is an image acquired…

Machine Learning · Computer Science 2017-11-21 Yair Rivenson , Zoltan Gorocs , Harun Gunaydin , Yibo Zhang , Hongda Wang , Aydogan Ozcan

When capturing and storing images, devices inevitably introduce noise. Reducing this noise is a critical task called image denoising. Deep learning has become the de facto method for image denoising, especially with the emergence of…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Haoyu Chen , Jinjin Gu , Yihao Liu , Salma Abdel Magid , Chao Dong , Qiong Wang , Hanspeter Pfister , Lei Zhu

Denoising is a fundamental imaging problem. Versatile but fast filtering has been demanded for mobile camera systems. We present an approach to multiscale filtering which allows real-time applications on low-powered devices. The key idea is…

Computer Vision and Pattern Recognition · Computer Science 2018-02-20 Sungjoon Choi , John Isidoro , Pascal Getreuer , Peyman Milanfar