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Dynamic Photoacoustic Computed Tomography (PACT) is an important imaging technique for monitoring physiological processes, capable of providing high-contrast images of optical absorption at much greater depths than traditional optical…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Youshen Xiao , Yiling Shi , Ruixi Sun , Hongjiang Wei , Fei Gao , Yuyao Zhang

Deep learning (DL)-based image reconstruction methods for photoacoustic computed tomography (PACT) have developed rapidly in recent years. However, most existing methods have not employed standardized datasets, and their evaluations rely on…

Medical Physics · Physics 2026-01-27 Panpan Chen , Seonyeong Park , Gangwon Jeong , Refik Mert Cam , Umberto Villa , Mark A. Anastasio

In photoacoustic tomography (PAT), the computation of the initial pressure distribution within an object from its time-dependent boundary measurements over time is considered. This problem can be approached from two well-established points…

Numerical Analysis · Mathematics 2025-07-04 Jaakko Kultima , Ronny Ramlau , Teemu Sahlström , Tanja Tarvainen

Photoacoustic (PA) imaging technology combines the advantages of optical imaging and ultrasound imaging, showing great potential in biomedical applications. Many preclinical studies and clinical applications urgently require fast,…

Image and Video Processing · Electrical Eng. & Systems 2024-08-13 Yuwei Zheng , Zijian Gao , Yuting Shen , Jiadong Zhang , Daohuai Jiang , Fengyu Liu , Feng Gao , Fei Gao

Conventional photoacoustic imaging may suffer from the limited view and bandwidth of ultrasound transducers. A deep learning approach is proposed to handle these problems and is demonstrated both in simulations and in experiments on a…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Guillaume Godefroy , Bastien Arnal , Emmanuel Bossy

In this article, we study several reconstruction methods for the inverse source problem of photoacoustic tomography (PAT) with spatially variable sound speed and damping. The backbone of these methods is the adjoint operators, which we…

Analysis of PDEs · Mathematics 2018-08-21 Linh V. Nguyen , Markus Haltmeier

Spectral Photon-Counting Computed Tomography (SPCCT) is a promising technology that has shown a number of advantages over conventional X-ray Computed Tomography (CT) in the form of material separation, artefact removal and enhanced image…

Image and Video Processing · Electrical Eng. & Systems 2020-03-10 Dimitris Kamilis , Mario Blatter , Nick Polydorides

In this paper, we propose a hybrid method to reconstruct the absorption coefficient by fluorescence photoacoustic tomography (FPAT), which combines a squeeze iterative method (SIM) and a nonlinear optimization method. The SIM is to use two…

Numerical Analysis · Mathematics 2019-01-30 Chao Wang , Tie Zhou

Recent advances in photoacoustic (PA) imaging have enabled detailed images of microvascular structure and quantitative measurement of blood oxygenation or perfusion. Standard reconstruction methods for PA imaging are based on solving an…

Signal Processing · Electrical Eng. & Systems 2020-04-17 MinWoo Kim , Geng-Shi Jeng , Ivan Pelivanov , Matthew O'Donnell

Recent advances in deep learning for tomographic reconstructions have shown great potential to create accurate and high quality images with a considerable speed-up. In this work we present a deep neural network that is specifically designed…

Computer Vision and Pattern Recognition · Computer Science 2020-09-07 Andreas Hauptmann , Felix Lucka , Marta Betcke , Nam Huynh , Jonas Adler , Ben Cox , Paul Beard , Sebastien Ourselin , Simon Arridge

This is the manuscript of the chapter for a planned Handbook of Mathematical Methods in Imaging that surveys the mathematical models, problems, and algorithms of the Thermoacoustic (TAT) and Photoacoustic (PAT) Tomography. TAT and PAT…

Analysis of PDEs · Mathematics 2011-10-04 Peter Kuchment , Leonid Kunyansky

Iterative model-based image reconstruction in photoacoustic tomography (PAT) enables principled incorporation of detector physics, object-related priors, and complex acquisition strategies. However, for three-dimensional (3D) imaging…

Inspired by the recent advances on minimizing nonsmooth or bound-constrained convex functions on models using varying degrees of fidelity, we propose a line search multigrid (MG) method for full-wave iterative image reconstruction in…

Numerical Analysis · Mathematics 2016-11-22 Ashkan Javaherian , Sean Holman

Photo-acoustic tomography is a coupled-physics (hybrid) medical imaging modality that aims to reconstruct optical parameters in biological tissues from ultrasound measurements. As propagating light gets partially absorbed, the resulting…

Analysis of PDEs · Mathematics 2020-01-08 Guillaume Bal , Adrian Kirkeby

Diffuse optical tomography (DOT) utilises near-infrared light for imaging spatially distributed optical parameters, typically the absorption and scattering coefficients. The image reconstruction problem of DOT is an ill-posed inverse…

Computational Physics · Physics 2021-12-15 Meghdoot Mozumder , Andreas Hauptmann , Ilkka Nissilä , Simon R. Arridge , Tanja Tarvainen

Among all tissue imaging modalities, photo-acoustic tomography (PAT) has been getting increasing attention in the recent past due to the fact that it has high contrast, high penetrability, and has capability of retrieving high resolution.…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Nadaparambil Aravindakshan Rejesh , Muthuvel Arigovindan

Photoacoustic Computed Tomography (PACT) is a major configuration of photoacoustic imaging, a hybrid noninvasive modality for both functional and molecular imaging. PACT has rapidly gained importance in the field of biomedical imaging due…

We propose a supervised machine learning approach for boosting existing signal and image recovery methods and demonstrate its efficacy on example of image reconstruction in computed tomography. Our technique is based on a local nonlinear…

Computer Vision and Pattern Recognition · Computer Science 2013-12-02 Joseph Shtok , Michael Zibulevsky , Michael Elad

Photoacoustic imaging is an emerging imaging modality that is based upon the photoacoustic effect. In photoacoustic tomography (PAT), the induced acoustic pressure waves are measured by an array of detectors and used to reconstruct an image…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Steven Guan , Amir Khan , Siddhartha Sikdar , Parag V. Chitnis

Optoacoustic tomography (OAT), also known as photoacoustic tomography, is an emerging computed biomedical imaging modality that exploits optical contrast and ultrasonic detection principles. Iterative image reconstruction algorithms that…

Medical Physics · Physics 2016-11-17 Kun Wang , Robert W Schoonover , Richard Su , Alexander Oraevsky , Mark A Anastasio