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Cross-Domain Recommendation (CDR) seeks to enhance item retrieval in low-resource domains by transferring knowledge from high-resource domains. While recent advancements in Large Language Models (LLMs) have demonstrated their potential in…
Predicting clinical outcomes to anti-cancer drugs on a personalized basis is challenging in cancer treatment due to the heterogeneity of tumors. Traditional computational efforts have been made to model the effect of drug response on…
In this paper, we study the problem of recommendation system where the users and items to be recommended are rich data structures with multiple entity types and with multiple sources of side-information in the form of graphs. We provide a…
Drug-drug interaction prediction is a crucial issue in molecular biology. Traditional methods of observing drug-drug interactions through medical experiments require significant resources and labor. This paper presents a medical knowledge…
Knowledge graph completion (KGC) aims to predict missing triples in knowledge graphs (KGs) by leveraging existing triples and textual information. Recently, generative large language models (LLMs) have been increasingly employed for graph…
Predicting disease trajectories from electronic health records (EHRs) is a complex task due to major challenges such as data non-stationarity, high granularity of medical codes, and integration of multimodal data. EHRs contain both…
Transformer architectures, capable of capturing sequential dependencies in the history of user interactions, have become the dominant approach in sequential recommender systems. Despite their success, such models consider sequence elements…
In recent years, deep learning has gained an indisputable success in computer vision, speech recognition, and natural language processing. After its rising success on these challenging areas, it has been studied on recommender systems as…
Modeling user preference from his historical sequences is one of the core problems of sequential recommendation. Existing methods in this field are widely distributed from conventional methods to deep learning methods. However, most of them…
Traditional model-based diagnosis relies on constructing explicit system models, a process that can be laborious and expertise-demanding. In this paper, we propose a novel framework that combines concepts of model-based diagnosis with deep…
In this paper, we consider the problem of disease diagnosis. Unlike the conventional learning paradigm that treats labels independently, we propose a knowledge-enhanced framework, that enables training visual representation with the…
Accurate identification of disease genes has consistently been one of the keys to decoding a disease's molecular mechanism. Most current approaches focus on constructing biological networks and utilizing machine learning, especially, deep…
Recently, there has been a surge of interest in Multi-Target Cross-Domain Recommendation (MTCDR), which aims to enhance recommendation performance across multiple domains simultaneously. Existing MTCDR methods primarily rely on…
As a pivotal tool to alleviate the information overload problem, recommender systems aim to predict user's preferred items from millions of candidates by analyzing observed user-item relations. As for alleviating the sparsity and cold start…
Deep learning methods exhibit promising performance for predictive modeling in healthcare, but two important challenges remain: -Data insufficiency:Often in healthcare predictive modeling, the sample size is insufficient for deep learning…
Cross-domain recommendation (CDR) aims to alleviate the data sparsity by transferring knowledge across domains. Disentangled representation learning provides an effective solution to model complex user preferences by separating intra-domain…
Repurposing existing drugs to treat new diseases is a cost-effective alternative to de novo drug development, but there are millions of potential drug-disease combinations to be considered with only a small fraction being viable. In silico…
In this paper, we propose a novel graph neural network-based recommendation model called KGLN, which leverages Knowledge Graph (KG) information to enhance the accuracy and effectiveness of personalized recommendations. We first use a…
Recommender systems is set up to address the issue of information overload in traditional information retrieval systems, which is focused on recommending information that is of most interest to users from massive information. Generally,…
Recommender systems are pivotal in enhancing user experiences across various web applications by analyzing the complicated relationships between users and items. Knowledge graphs(KGs) have been widely used to enhance the performance of…