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Cross-domain recommendation (CDR) aims to leverage the correlation of users' behaviors in both the source and target domains to improve the user preference modeling in the target domain. Conventional CDR methods typically explore the…

Information Retrieval · Computer Science 2023-06-09 Haokai Ma , Ruobing Xie , Lei Meng , Xin Chen , Xu Zhang , Leyu Lin , Jie Zhou

Dynamic treatment regimes (DTRs) are critical to precision medicine, optimizing long-term outcomes through personalized, real-time decision-making in evolving clinical contexts, but require careful supervision for unsafe treatment risks.…

Machine Learning · Computer Science 2025-06-10 Yishan Shen , Yuyang Ye , Hui Xiong , Yong Chen

Using knowledge graphs to assist deep learning models in making recommendation decisions has recently been proven to effectively improve the model's interpretability and accuracy. This paper introduces an end-to-end deep learning model,…

Information Retrieval · Computer Science 2024-04-11 Chen Li , Yang Cao , Ye Zhu , Debo Cheng , Chengyuan Li , Yasuhiko Morimoto

Cross domain recommender systems have been increasingly valuable for helping consumers identify the most satisfying items from different categories. However, previously proposed cross-domain models did not take into account bidirectional…

Information Retrieval · Computer Science 2019-10-14 Pan Li , Alexander Tuzhilin

Medical diagnosis is the process of making a prediction of the disease a patient is likely to have, given a set of symptoms and observations. This requires extensive expert knowledge, in particular when covering a large variety of diseases.…

Artificial Intelligence · Computer Science 2022-04-29 Niclas Heilig , Jan Kirchhoff , Florian Stumpe , Joan Plepi , Lucie Flek , Heiko Paulheim

Recommender systems are designed to predict user preferences over collections of items. These systems process users' previous interactions to decide which items should be ranked higher to satisfy their desires. An ensemble recommender…

Information Retrieval · Computer Science 2023-06-23 Alireza Gharahighehi , Celine Vens , Konstantinos Pliakos

We introduce a framework for AI-based medical consultation system with knowledge graph embedding and reinforcement learning components and its implement. Our implement of this framework leverages knowledge organized as a graph to have…

Machine Learning · Computer Science 2021-08-31 Yining Huang , Meilian Chen , Keke Tang

Clinicians prescribe antibiotics by looking at the patient's health record with an experienced eye. However, the therapy might be rendered futile if the patient has drug resistance. Determining drug resistance requires time-consuming…

Artificial Intelligence · Computer Science 2023-03-09 Honglin Shu , Pei Gao , Lingwei Zhu , Zheng Chen

Computational Drug Repositioning (CDR) is the task of discovering potential new indications for existing drugs by mining large-scale heterogeneous drug-related data sources. Leveraging the patient-level temporal ordering information between…

Applications · Statistics 2017-03-01 Zhaobin Kuang , James Thomson , Michael Caldwell , Peggy Peissig , Ron Stewart , David Page

In the last decades, people have been consuming and combining more drugs than before, increasing the number of Drug-Drug Interactions (DDIs). To predict unknown DDIs, recently, studies started incorporating Knowledge Graphs (KGs) since they…

Artificial Intelligence · Computer Science 2023-08-14 Lizzy Farrugia , Lilian M. Azzopardi , Jeremy Debattista , Charlie Abela

Multi-task learning (MTL) aims at learning related tasks in a unified model to achieve mutual improvement among tasks considering their shared knowledge. It is an important topic in recommendation due to the demand for multi-task prediction…

Information Retrieval · Computer Science 2023-02-10 Yuhao Wang , Ha Tsz Lam , Yi Wong , Ziru Liu , Xiangyu Zhao , Yichao Wang , Bo Chen , Huifeng Guo , Ruiming Tang

Knowledge graphs (KGs) are gaining prominence in Healthcare AI, especially in drug discovery and pharmaceutical research as they provide a structured way to integrate diverse information sources, enhancing AI system interpretability. This…

Artificial Intelligence · Computer Science 2023-09-29 Satvik Garg , Shivam Parikh , Somya Garg

Drug combination therapy has become a increasingly promising method in the treatment of cancer. However, the number of possible drug combinations is so huge that it is hard to screen synergistic drug combinations through wet-lab…

Machine Learning · Computer Science 2021-07-07 J. Wang , X. Liu , S. Shen , L. Deng , H. Liu*

A pharmacological effect of a drug on cells, organs and systems refers to the specific biochemical interaction produced by a drug substance, which is called its mechanism of action. Drug repositioning (or drug repurposing) is a fundamental…

Machine Learning · Computer Science 2020-05-19 Dehua Chen , Amir Jalilifard , Adriano Veloso , Nivio Ziviani

Personalized recommendations are popular in these days of Internet driven activities, specifically shopping. Recommendation methods can be grouped into three major categories, content based filtering, collaborative filtering and machine…

Information Retrieval · Computer Science 2021-01-11 Yuhao Mao , Serguei A. Mokhov , Sudhir P. Mudur

Cross-domain recommendation (CDR) offers a promising solution to the data sparsity problem by enabling knowledge transfer across source and target domains. However, many recent CDR models overlook crucial issues such as privacy as well as…

Machine Learning · Computer Science 2024-11-05 Ziqi Yang , Zhaopeng Peng , Zihui Wang , Jianzhong Qi , Chaochao Chen , Weike Pan , Chenglu Wen , Cheng Wang , Xiaoliang Fan

Recent years have witnessed the fast development of the emerging topic of Graph Learning based Recommender Systems (GLRS). GLRS mainly employ the advanced graph learning approaches to model users' preferences and intentions as well as…

Information Retrieval · Computer Science 2020-04-27 Shoujin Wang , Liang Hu , Yan Wang , Xiangnan He , Quan Z. Sheng , Mehmet Orgun , Longbing Cao , Nan Wang , Francesco Ricci , Philip S. Yu

Knowledge graphs and structural causal models have each proven valuable for organizing biomedical knowledge and estimating causal effects, but remain largely disconnected: knowledge graphs encode qualitative relationships focusing on facts…

Artificial Intelligence · Computer Science 2025-05-13 Sumyyah Toonsi , Paul Schofield , Robert Hoehndorf

To alleviate the cold start problem caused by collaborative filtering in recommender systems, knowledge graphs (KGs) are increasingly employed by many methods as auxiliary resources. However, existing work incorporated with KGs cannot…

Machine Learning · Computer Science 2020-09-10 Xinze Lyu , Guangyao Li , Jiacheng Huang , Wei Hu

Cross-domain recommendation (CDR) can help customers find more satisfying items in different domains. Existing CDR models mainly use common users or mapping functions as bridges between domains but have very limited exploration in fully…

Information Retrieval · Computer Science 2022-06-28 Li Zhang , Yan Ge , Jun Ma , Jianmo Ni , Haiping Lu
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